Results 111 to 120 of about 1,122,864 (370)

Transient gene expression in serum-free suspension-growing mammalian cells for the production of foot-and-mouth disease virus empty capsids. [PDF]

PLoS ONE, 2013
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals. It produces severe economic losses in the livestock industry. Currently available vaccines are based on inactivated FMD virus (FMDV).
Ana Clara Mignaqui, Vanesa Ruiz, Sylvie Perret, Gilles St-Laurent, Parminder Singh Chahal, Julia Transfiguracion, Ayelén Sammarruco, Victoria Gnazzo, Yves Durocher, Andrés Wigdorovitz   +9 more
doaj   +1 more source

SARS CoV subunit vaccine: Antibodymediated neutralisation and enhancement [PDF]

, 2012
1. A SARS vaccine was produced based on recombinant native full-length Spike-protein trimers (triSpike) and efficient establishment of a vaccination procedure in rodents. 2.
Altmeyer, R, Bruzzone, R, Cheung, CY, Daeron, M, Dutry, I, Escriou, N, Jaume, M, Kam, YW, Kien, F, Li, PH, Nal, B, Peiris, JSM, Roberts, A, Subbarao, K, Yip, MS   +14 more
core   +1 more source

Protection of pigs against challenge with virulent Streptococcus suis serotype 2 strains by a muramidase-released protein and extracellular factor vaccine [PDF]

, 2001
The efficacy of a muramidase-released protein (MRP) and extracellular factor (EF) vaccine in preventing infection and disease in pigs challenged either with a homologous or a heterologous Streptococcus suis serotype 2 strain (MRP EF ) was compared with ...
Smith, H.E., Stockhofe Zurwieden, N., Vecht, U., Wisselink, H.J.   +3 more
core   +2 more sources

Recent Advances in Subunit Vaccine Carriers

Vaccines, 2016
The lower immunogenicity of synthetic subunit antigens, compared to live attenuated vaccines, is being addressed with improved vaccine carriers. Recent reports indicate that the physio-chemical properties of these carriers can be altered to achieve optimal antigen presentation, endosomal escape, particle bio-distribution, and cellular trafficking.
Abhishek Vartak, Steven J. Sucheck
openaire   +3 more sources

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Experience and Challenges from Clinical Trials with Malaria Vaccines in Africa. [PDF]

, 2013
Malaria vaccines are considered amongst the most important modalities for potential elimination of malaria disease and transmission. Research and development in this field has been an area of intense effort by many groups over the last few decades ...
A Nyika, A Olotu, A Roca-Feltrer, AA Holder, AJ Luty, AVS Hill, B Moonen, Bernhards Ogutu, Beverly Msambichaka, BF Chumpitazi, Bouharoun-Tayoun H Druilhe P, C Guinovart, C Roussilhon, C Swysen, DA Chokshi, DA Diallo, E Peduzzi, Eakin, Bull SS, Riley K,Reeves MM, Gutierrez S, McLaughlin P, FM Ndungu, FM Ndungu, FM Thompson, Grace Mwangoka, H Bouharoun-Tayoun, HL Smits, I Nebie, J Schantz-Dunn, JL Sarthou, K Miura, K Shubis, KE Kester, KE Kester, KP Asante, L Schwartz, M Roestenberg, M Roestenberg, Marcel Tanner, Maxmillian Mpina, MP Girad, Nahya Salim, NC Iriemenam, NJ White, OK Doumbo, PG Cech, PL Alonso, PL Alonso, PL Alonso, PO Tindana, R Chilengi, RR Taylor, S Casares, Salim Abdulla, Seif Shekalaghe, Shubis Kafuruki, SJ Rogerson, SL Hoffman, ST Agnandji, ST Agnandji, T Smith, T Smith, T Smith, TA Lang, The malERA Consultative Group on Vaccines, Tutu Mzee, V Gardette, V Moorthy, WHO, WHO, YP Shi   +67 more
core   +3 more sources

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Target antigen screening and development of a multi-component subunit vaccine against Mycoplasma synoviae in chickens

Frontiers in Cellular and Infection Microbiology
IntroductionMycoplasma synoviae (MS) is a globally important avian pathogen causing infectious synovitis and respiratory diseases in poultry, leading to significant economic losses.
Xiaomei Sun, Xiaomei Sun, Xiaomei Sun, Mingyong Deng, Chuxing Cheng, Ya Zhao, Ya Zhao, Ya Zhao, Zuqing Liu, Yu Yang, Qiaoxia Xu, Rong Yao, Min Hu, Meilin Jin, Meilin Jin, Meilin Jin, Meilin Jin, Meilin Jin, Chao Kang, Chao Kang   +19 more
doaj   +1 more source

Antigen-specific acquired immunity in human brucellosis: implications for diagnosis, prognosis, and vaccine development. [PDF]

, 2012
Brucella spp., are Gram negative bacteria that cause disease by growing within monocyte/macrophage lineage cells. Clinical manifestations of brucellosis are immune mediated, not due to bacterial virulence factors.
Alessandro eSette, Anthony P Cannella, Eduardo eGotuzzo, Joseph M Vinetz, Joseph M Vinetz, Li eLiang, Mayuko eSaito, Philip eFelgner, Renee M Tsolis   +8 more
core   +1 more source

Herpes zoster subunit vaccine for patients initiating a Janus kinase inhibitor [PDF]

, 2022
Reid A. Waldman, Kelley Sharp, Jónas A. Aðalsteinsson, Jane M. Grant‐Kels   +3 more
openalex   +1 more source