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SARS-CoV-2 subunit vaccine adjuvants and their signaling pathways
Expert Review of Vaccines, 2021 Introduction Vaccines are the agreed upon weapon against the COVID-19 pandemic. This review discusses about COVID-19 subunit vaccines adjuvants and their signaling pathways, which could provide a glimpse into the selection of appropriate adjuvants for ...
D. Mekonnen, H. M. Mengist, T. Jin
semanticscholar +1 more source
Virology Journal, 2023 Background Pseudorabies (PR) (also called Aujeszky’s disease, AD) is a serious infectious disease affecting pigs and other animals worldwide. The emergence of variant strains of pseudorabies virus (PRV) since 2011 has led to PR outbreaks in China and a ...
Hong-liang Zhang +6 more
doaj +1 more source
Vaccines, 2021 The development of COVID-19 vaccines is critical in controlling global health issues under the COVID-19 pandemic. The subunit vaccines are the safest and most widely used vaccine platform and highly effective against a multitude of infectious diseases ...
Soo-Kyung Jeong +7 more
semanticscholar +1 more source
Journal of General Virology, 1983 Conclusions The secondary and tertiary structures of the rabies virus spike G protein are important for its ability to induce VN antibodies and confer immunity to the host. For a subunit peptide vaccine to be as effective as the native spike G protein, it would appear that the amino acid sequence comprising the antigenic determinant for VN antibody ...
W H, Wunner +3 more
openaire +2 more sources
Reducing Campylobacter jejuni colonization in broiler chickens by in-feed supplementation with hyperimmune egg yolk antibodies [PDF]
, 2019 Campylobacter infections sourced mainly to poultry products, are the most important bacterial foodborne zoonoses worldwide. No effective measures to control these infections in broiler production exist to date.
Canessa, Stefano +8 more
core +1 more source
PLoS ONE, 2012 Recent studies have demonstrated the effectiveness of vaccine delivery to the skin by vaccine-coated microneedles; however there is little information on the effects of adjuvants using this approach for vaccination.
William C Weldon +8 more
doaj +1 more source
npj Vaccines, 2022 Protein or peptide-based subunit vaccines have generated excitement and renewed interest in combating human cancer or COVID-19 outbreak. One major concern for subunit vaccine application is the weak immune responses induced by protein or peptides ...
Ning Yang +6 more
doaj +1 more source
PLoS ONE, 2023 Subunit vaccines feature critical advantages over other vaccine platforms such as stability, price, and minimal adverse effects. To maximize immunological protection of subunit vaccines, adjuvants are considered as main components that are formulated ...
Sedthawut Laotee +15 more
doaj +1 more source
A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein
Cell Research, 2022 The emerging SARS-CoV-2 variants, commonly with many mutations in S1 subunit of spike (S) protein are weakening the efficacy of the current vaccines and antibody therapeutics.
W. Pang +25 more
semanticscholar +1 more source
Computational modeling of TC0583 as a putative component of the Chlamydia muridarum V-type ATP synthase complex and assessment of its protective capabilities as a vaccine antigen. [PDF]
, 2016 Numerous Chlamydia trachomatis proteins have been identified as potential subunit vaccines, of which the major outer-membrane protein (MOMP) has, so far, proven the most efficacious. Recently, subunit A of the V-type ATP synthase (ATPase; TC0582) complex
Barta, Michael L +4 more
core +1 more source