Results 11 to 20 of about 218,507 (292)
Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling
Cell Reports, 2021 Summary: Succinate functions both as a classical TCA cycle metabolite and an extracellular metabolic stress signal sensed by the mainly Gi-coupled succinate receptor SUCNR1. In the present study, we characterize and compare effects and signaling pathways
Mette Trauelsen +11 more
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Frontiers in Microbiology, 2021 The plant growth-promoting Acinetobacter sp. SK2 isolated from Vigna radiata rhizosphere was characterized for mineral phosphate solubilization (MPS).
Krishna Bharwad +2 more
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Succinate metabolism and its regulation of host-microbe interactions
Gut microbes, 2023 Succinate is a circulating metabolite, and the relationship between abnormal changes in the physiological concentration of succinate and inflammatory diseases caused by the overreaction of certain immune cells has become a research focus.
Yi Wei +4 more
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Biomolecules, 2023 Uterine endometrial cancer (UEC) is an estrogen-related tumor. Succinate and heme metabolism play important roles in the progression of multiple tumors.
Jia-Jing Lu +9 more
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A Review on Properties and Application of Bio-Based Poly(Butylene Succinate)
Polymers, 2021 Researchers and companies have increasingly been drawn to biodegradable polymers and composites because of their environmental resilience, eco-friendliness, and suitability for a range of applications.
S. Rafiqah +7 more
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Frontiers in Immunology, 2023 Hepatocellular carcinoma (HCC) is the most prevalent primary liver malignancy worldwide and is associated with a poor prognosis. Sophisticated molecular mechanisms and biological characteristics need to be explored to gain a better understanding of HCC ...
Wenhui Zhang +3 more
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Frontiers in Cell and Developmental Biology, 2023 Succinate serves as an essential circulating metabolite within the tricarboxylic acid (TCA) cycle and functions as a substrate for succinate dehydrogenase (SDH), thereby contributing to energy production in fundamental mitochondrial metabolic pathways ...
Wenhui Zhang, Ren Lang
semanticscholar +1 more source
A critical role for heme synthesis and succinate in the regulation of pluripotent states transitions
eLife, 2023 Using embryonic stem cells (ESCs) in regenerative medicine or in disease modeling requires a complete understanding of these cells. Two main distinct developmental states of ESCs have been stabilized in vitro, a naïve pre-implantation stage and a primed ...
Damien Detraux +7 more
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Microbiome, 2022 Succinate is produced by both human cells and by gut bacteria and couples metabolism to inflammation as an extracellular signaling transducer. Circulating succinate is elevated in patients with obesity and type 2 diabetes and is linked to numerous ...
Isabel Huber-Ruano +19 more
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Frontiers in Aging, 2022 Blue light (BL) is becoming increasingly prevalent in artificial illumination, raising concerns about its potential health hazard to humans. In fact, there is evidence suggesting that acute BL exposure may lead to oxidative stress and death of retinal ...
Jun Yang +10 more
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