Results 161 to 170 of about 433,622 (361)

Survey of Human Mitochondrial Diseases Using New Genomic/Proteomic Tools [PDF]

, 2001
BACKGROUND. We have constructed Bayesian prior-based, amino-acid sequence profiles for the complete yeast mitochondrial proteome and used them to develop methods for identifying and characterizing the context of protein mutations that give rise to human ...
Mohr, Scott C., Plasterer, Thomas N., Smith, Temple F.   +2 more
core   +2 more sources

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Sensitivity of Irish Pyrenopeziza brassicae populations to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides

Pest Management Science, EarlyView.
For three collections of Irish Pyrenopeziza brassicae populations fungicide sensitivity status to methyl benzimidazole carbamate (MBC), quinone outside inhibitor (QoI) and succinate dehydrogenase inhibitor (SDHI) fungicides was determined using sensitivity screening in vitro. Molecular mechanisms of insensitivity have been identified for MBC and QoI in
Diana E Bucur, Yong‐Ju Huang, Bruce DL Fitt, Steven Kildea   +3 more
wiley   +1 more source

Characteristics of fungicide resistance in Asian soybean rust (Phakopsora pachyrhizi) in Paraguay for 2022–2023: insights from genetic mutations and molecular dynamics simulations

Pest Management Science, EarlyView.
Phakopsora pachyrhizi in Paraguay showed diverse resistance to DMI, SDHI, and QoI fungicides at both regional and intra‐field levels, likely driven by target mutation genes. Abstract BACKGROUND Phakopsora pachyrhizi, the causative agent of Asian soybean rust, poses a major threat to soybean production in South America. The rising incidence of fungicide
Ryusuke Hagihara, Ryo Okada, Takuya Hayashi, Hideaki Tateishi, Wilfrido Morel, Naoki Yamanaka   +5 more
wiley   +1 more source

A new method to measure EC50 reveals cultivar‐specific fungicide resistance and very high diversity within experimental field populations of Zymoseptoria tritici

Pest Management Science, EarlyView.
We isolated Zymoseptoria tritici strains from a diverse wheat field and quantified fungicide resistance using a novel plate assay. We found high diversity in fungicide sensitivity and host–fungicide–pathogen interactions. Abstract BACKGROUND Zymoseptoria tritici causes Septoria tritici blotch (STB), the most damaging wheat disease in Europe. In Europe,
Firas Talas, Jessica Stapley, Bruce A McDonald   +2 more
wiley   +1 more source

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Cell, 2016
E. Mills, B. Kelly, A. Logan, Ana S. H. Costa, M. Varma, C. Bryant, Panagiotis Tourlomousis, J. Däbritz, E. Gottlieb, I. Latorre, S. Corr, G. McManus, D. Ryan, H. Jacobs, H. Jacobs, M. Szibor, M. Szibor, M. Szibor, R. Xavier, T. Braun, C. Frezza, M. Murphy, L. O’Neill   +22 more
semanticscholar   +1 more source

High prevalence of founder mutations of the succinate dehydrogenase genes in the Netherlands [PDF]

, 2011
Erik F. Hensen, Nicolette van Duinen, Jeroen C. Jansen, EPM Corssmit, CMJ Tops, JA Romijn, AHJT Vriends, AGL van der Mey, CJ Cornelisse, Peter Devilee, J-P Bayley   +10 more
openalex   +1 more source

Sensitivity to demethylation‐inhibiting fungicides and induced expression of CYP51 associated with tebuconazole resistance in Alternaria species on mandarin in Brazil

Pest Management Science, EarlyView.
Tebuconazole‐resistant isolates overexpress CYP51 and, when tested at field rates, did not reduce ABS severity, whereas difenoconazole and mefentrifluconazole remained effective. Abstract BACKGROUND Alternaria brown spot (ABS), caused by Alternaria spp., is an important disease affecting mandarin production in several citrus‐growing regions worldwide ...
Thiago de Aguiar Carraro, Yong Luo, Boris X. Camiletti, Themis J. Michailides, Victor Gabri, Geraldo José Silva‐Junior, Lilian Amorim, Louise Larissa May De Mio   +7 more
wiley   +1 more source

Isolation and Characterization of Glycerol-3-Phosphate Dehydrogenase-Defective Mutants of \u3cem\u3eNeurospora crassa\u3c/em\u3e [PDF]

, 1978
Three glycerol-nonutilizing mutants deficient in the mitochondrial glycerol-3-phosphate (G3P) dehydrogenase (EC 1.1.99.5) were isolated from inlts derivatives of Neurospora crassa following inositolless death at elevated temperatures on minimal glycerol ...
Courtright, James B., Denor, Patrick F.
core   +1 more source

A H258Y mutation in subunit B of the succinate dehydrogenase complex of the spider mite Tetranychus urticae confers resistance to cyenopyrafen and pyflubumide, but likely reinforces cyflumetofen binding and toxicity

, 2022
Christine Njiru, Corinna Saalwaechter, Oliver Gutbrod, Sven Geibel, Nicky Wybouw, Thomas Van Leeuwen   +5 more
openalex   +2 more sources