Results 181 to 190 of about 67,725 (262)

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, Volume 269, Issue 4-5, Page 387-398, August 2026.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

Olverembatinib, a multikinase inhibitor that modulates lipid metabolism, in advanced succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 1b study and translational research. [PDF]

Signal Transduct Target Ther
Qiu HB, Liang Z, Yang J, Zhou Y, Zhou ZW, Wan XB, Li N, Tao KX, Li Y, Wu X, Yang C, Chen Z, Wang H, Men L, Xiong Y, Liu L, Yang D, Zhai Y, Xu RH.   +18 more
europepmc   +1 more source

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

VIEW Medicine, Volume 1, Issue 1, August 2026.
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng, Qing Cong, Ling Lin, Liang Qiao   +3 more
wiley   +1 more source

Correction: Approaches to reduce succinate accumulation by restoration of succinate dehydrogenase activity in cultured adrenal cells. [PDF]

J Cell Sci
europepmc   +1 more source

Succinate dehydrogenase-deficient gastrointestinal stromal tumor of the stomach: EUS and contrast-enhanced EUS features (with videos). [PDF]

Endosc Ultrasound
Martino A, Fiorentino R, Crolla E, Anastasio L, Campione S, Picascia S, de Leone A, Dell'Aversano Orabona G, Di Serafino M, Molino C, Riccardi F, Lombardi G.   +11 more
europepmc   +1 more source

Putative Mechanisms for Initial Reaction of Anaerobic Benzene Degradation Presumably Involving a Flavoprotein

Environmental Microbiology, Volume 28, Issue 8, August 2026.
Anaerobic biodegradation of benzene by sulphate‐reducing strain BzS1 was studied by combining genomics, differential proteomics and targeted metabolite analyses. Strain BzS1 has an exceptionally streamlined metabolism. A highly abundant heterotrimeric flavoprotein may add benzene to either enolpyruvate or glutaconyl‐CoA followed by channelling into the
Florin Musat, Lars Wöhlbrand, Rene Jarling, Michael Kube, Niculina Musat, Patrick Becker, Stefan Bruns, Richard Reinhardt, Rudolf Amann, Friedrich Widdel, Heinz Wilkes, Ralf Rabus   +11 more
wiley   +1 more source

Case Report: Metastatic succinate dehydrogenase-deficient gastrointestinal stromal tumor treated with chemotherapy and immune checkpoint inhibitor. [PDF]

Front Oncol
Claessens A, Plaza JE, Blay JY.
europepmc   +1 more source

South African Herbal Teas and Diabetes‐Mediated Mitochondrial Dysfunction: Emerging Evidence and Mechanistic Insights

Journal of Food Science, Volume 91, Issue 8, August 2026.
ABSTRACT Type 2 diabetes mellitus (T2DM) is a central component of the metabolic syndrome (MetS) and is associated with underlying mitochondrial dysfunction. Disruption of mitochondrial homeostasis impairs cellular energy metabolism and contributes to the overproduction of reactive oxygen species (ROS), leading to oxidative stress, chronic inflammation,
Shanika Reddy, Naeem Sheik Abdul, Taskeen Fathima Docrat, Jeanine Marnewick   +3 more
wiley   +1 more source

Renal cell carcinoma with succinate dehydrogenase A mutation: A case report and literature review. [PDF]

Oncol Lett
Hu M, Wang XT, Xiao XX, Rao Q, Fan LF, Yue JQ.   +5 more
europepmc   +1 more source

Metabolic Flux and Growth Profiling of Megasphaera cerevisiae for Medium‐Chain Fatty Acid Synthesis

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Characterising the metabolism of medium‐chain fatty acids in Megasphaera cerevisiae, based on genome‐scale metabolic modelling and integration with experimental data obtained from controlled bioreactor cultivations. The iterative approach aligns in silico predictions with empirical observations and a refined model was obtained.
Wael Sabra, Sonia Villotti, Joachim Fensterle, An‐Ping Zeng, Ahmed M. Haddad   +4 more
wiley   +1 more source