Results 191 to 200 of about 67,725 (262)

Succinate Dehydrogenase and Human Disease: Novel Insights into a Well-Known Enzyme. [PDF]

Biomedicines
Esteban-Amo MJ, Jiménez-Cuadrado P, Serrano-Lorenzo P, de la Fuente MÁ, Simarro M.   +4 more
europepmc   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, Volume 81, Issue 8, Page 2675-2712, August 2026.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

Identification of Succinate Dehydrogenase Gene Variant Carriers by Blood Biomarkers. [PDF]

J Endocr Soc
Gebhardt M, Kunath C, Fröbel D, Funk AM, Peitzsch M, Nölting S, Deutschbein T, Januszewicz A, Timmers HJLM, Robledo M, Jahn A, Constantinescu G, Eisenhofer G, Pamporaki C, Richter S.   +14 more
europepmc   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

Cell Proliferation, Volume 59, Issue 8, August 2026.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao, Lin Qi, Guijun Zou, Xingpeng Yang, Yizhao Ma, Zhifu Li, Xiaohui Du, Pengyue Zhao   +7 more
wiley   +1 more source

Resistance‐exercise‐induced stress intervenes in TGF‐β signaling by cooperatively downregulating nuclear αB‐crystallin and SMAD4 in human skeletal muscle fibers

The FEBS Journal, Volume 293, Issue 15, Page 4624-4644, August 2026.
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf, Cassandra Duda, Tihomir Kostov, Patrick Diel, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert, Daniel Jacko   +7 more
wiley   +1 more source

High Succinate peak in Magnetic Resonance Spectroscopy: A Diagnostic Clue for the Leukoencephalopathy Result from Succinate Dehydrogenase Deficiencies. [PDF]

Iran J Child Neurol
Koc Ucar H, Orgun LT, Arhan E, Serdaroglu A, Aydin K.   +4 more
europepmc   +1 more source

Polyesterase activity and thermostability of carboxylesterases from Thermoleophilum album YS‐3

The FEBS Journal, Volume 293, Issue 15, Page 4724-4743, August 2026.
Three novel α/β‐hydrolases from thermophilic bacterium Thermoleophilum album display carboxylesterase and polyesterase activity. These enzymes hydrolyse PET, PLA and PCL both at high and moderate temperatures. TA21 shows superior activity, efficiently converting MHET to terephthalic acid. Structural features underlying substrate binding highlight their
Tatyana N. Chernikova, Anna N. Khusnutdinova, Hairong Ma, Manuel Ferrer, Olga V. Golyshina, Alexander F. Yakunin, Peter N. Golyshin   +6 more
wiley   +1 more source

The New Nematicide Cyclobutrifluram Targets the Mitochondrial Succinate Dehydrogenase Complex in Bursaphelenchus xylophilus. [PDF]

Int J Mol Sci
Liu W, Shao H, Qi D, Huang X, Chen J, Zhou L, Guo K.   +6 more
europepmc   +1 more source

The multidimensional regulation roles and mechanisms of calcium in fruit quality

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2747-2767, August 2026.
This review explores how calcium signaling molecule integrates plant hormones, environmental cues, and developmental signals to influence external fruit traits, internal nutritional properties, and physiological disorders. ABSTRACT Calcium (Ca2+), a dual‐functional mineral that serves both as an essential structural factor and a signaling molecule ...
Fei Jiang, Siyang Gao, Mengdi Li, Zeqi Zhao, Chengwei Yang, Ji‐Hong Liu, Chunlong Li   +6 more
wiley   +1 more source