Results 191 to 200 of about 233,572 (253)

Effects of exercise followed by a low‐carbohydrate diet on peak fat oxidation and mitochondrial coupling control and efficiency in healthy trained men

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of study design and key findings. Ten trained men completed a randomized crossover study with two conditions differing in muscle glycogen availability (high versus low), achieved through a glycogen depletion protocol followed by a high‐ or low‐carbohydrate diet.
K. K. Lange   +10 more
wiley   +1 more source

Lachnospiraceae in the Food–Gut Axis: A Critical Review of Dietary Modulation, Immune Regulation, and Translational Barriers

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 6, November 2026.
ABSTRACT The interplay between diet, gut microbiota, and host immunity is central to food science. The Lachnospiraceae family ferments dietary fibers to produce short‐chain fatty acids (SCFAs), notably butyrate and propionate, with immunomodulatory potential. This critical review distinguishes established findings from hypotheses.
Ruijun Wang   +4 more
wiley   +1 more source

4‐Octyl Itaconate Attenuates Age‐Induced Parotid Gland Dysfunction Through the Suppression of Fibrosis and Lipid Deposition by AMPKα/PPARα and the Inhibition of Oxidative Stress via the AMPKα/Nrf2 Signaling Pathway

open access: yesThe FASEB Journal, Volume 40, Issue 19, 15 October 2026.
4‐Octyl itaconate (4‐OI) attenuates age‐induced parotid gland dysfunction through the suppression of fibrosis and lipid deposition by AMPKα/PPARα and the inhibition of oxidative stress via the AMPKα/Nrf2 signaling pathway. 4‐OI activates AMPKα, which in turn stimulates both the PPARα and Nrf2 pathways. Activation of PPARα enhances FAO and reduces lipid
Yun Chen   +6 more
wiley   +1 more source

Unraveling a Diagnostic Enigma: A TECPR2 Case Solved Through Multi‐Omic Genomics

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2338-2344, October 2026.
ABSTRACT TECPR2 is a key regulator of autophagy, encoded by the TECPR2 gene. Pathogenic variants in this gene have been linked to a rare hereditary sensory and autonomic neuropathy with intellectual disability (HSAN9). We report a teenage female with a syndromic intellectual disability disorder associated with neuromuscular abnormalities.
Teresa Zhao   +123 more
wiley   +1 more source

Succinate Dehydrogenase Pathogenic Variants Among Older Adults With Head and Neck Paragangliomas. [PDF]

open access: yesLaryngoscope Investig Otolaryngol
Bellamkonda N   +5 more
europepmc   +1 more source

Spray‐Dried Engineered Escherichia coli Whole‐Cell Biocatalysts Enable Cell Recycling and In Vivo α‐Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 10, Page 2629-2642, October 2026.
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian   +4 more
wiley   +1 more source

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