Results 201 to 210 of about 433,622 (361)

Heterologous plastoquinone production using a newly identified O2‐dependent cyanobacterial hydroxylase

open access: yesThe FEBS Journal, EarlyView.
In this study, we confirm that PlqH is the hydroxylase operating in plastoquinone biosynthesis in photosynthetic cyanobacteria (Cyanobacteriia). Our phylogenetic analyses demonstrate that cyanobacterial PlqH homologues originated from hydroxylases involved in ubiquinone biosynthesis in bacteria. Plastoquinone production in Escherichia coli was achieved
Morgane Roger‐Margueritat   +7 more
wiley   +1 more source

Dietary anthocyanidin pelargonidin activates G protein‐coupled receptor 35

open access: yesThe FEBS Journal, EarlyView.
Pelargonidin, a red‐fruit‐derived anthocyanidin, was newly identified as a dietary agonist of GPR35, a metabolite‐sensing GPCR implicated in anti‐inflammation. Through screening of dietary compounds, pelargonidin emerged as a potent GPR35 agonist, attenuating inflammation in human intestinal cells.
Fumie Nakashima   +11 more
wiley   +1 more source

Comparative analysis of metabolic and functional cardiac alterations in diet‐ and genetically induced mouse models of cardiac dysfunction

open access: yesThe FEBS Journal, EarlyView.
Dietary and genetic stress trigger different routes to heart failure. In mice, a carbohydrate‐free high‐fat diet caused mitochondrial dysfunction and impaired energy production with preserved pumping function, while genetic obesity led to heart enlargement, fibrosis, and reduced function.
Christiane Ott   +9 more
wiley   +1 more source

Coenzyme A mitigates cystine‐deprivation‐induced ferroptosis by suppressing the iron‐starvation response

open access: yesThe FEBS Journal, EarlyView.
Cystine (Cys2) deprivation in pancreatic cancer cells induces oxidative stress that destabilizes cytosolic iron–sulfur cluster (ISC) proteins, triggering an iron‐regulatory protein (IRP)‐mediated iron‐starvation response (ISR). This leads to increased iron uptake (via TFRC), an expanded labile iron pool, and ferroptosis.
Mingjun Tan   +8 more
wiley   +1 more source

Structural basis of menaquinone reduction by succinate dehydrogenase from Chloroflexus aurantiacus. [PDF]

open access: yesNat Commun
Zhang X   +12 more
europepmc   +1 more source

Functional and biochemical characterization of the Toxoplasma gondii succinate dehydrogenase complex. [PDF]

open access: yesPLoS Pathog, 2023
Silva MF   +4 more
europepmc   +1 more source

Papillary renal cell carcinoma, formerly known as Type 2: a single institutional study addressing histologic and molecular features

open access: yesHistopathology, EarlyView.
Papillary renal cell carcinoma (pRCC) accounts for 15%–20% of RCC cases and is the second most common histologic subtype of RCC. In contrast to other common RCC subtypes, there continues to be ongoing debate about how to classify RCCs with papillary architecture and eosinophilic cytoplasm, given the heterogeneity of histologic, IHC and molecular ...
Melissa Yuwono Tjota   +3 more
wiley   +1 more source

A Rare Leukoencephalopathy: Succinate Dehydrogenase Deficiency

open access: yesTürk Nöroloji Dergisi, 2017
Özdem Ertürk Çetin   +2 more
doaj   +1 more source

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