Results 21 to 30 of about 433,622 (361)

Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster

Proceedings of the National Academy of Sciences of the United States of America, 2021
Significance Targeting energy metabolism in Mycobacterium tuberculosis has emerged as a new paradigm in antituberculosis drug discovery. Succinate dehydrogenase is considered the regulator of respiration in M. tuberculosis.
Xiaoting Zhou, Yan Gao, Weiwei Wang, Xiaolin Yang, Xiuna Yang, Fengjiang Liu, Yanting Tang, S. Lam, G. Shui, Lu Yu, C. Tian, L. Guddat, Quan Wang, Z. Rao, H. Gong   +14 more
semanticscholar   +1 more source

Succinate Mediates Tumorigenic Effects via Succinate Receptor 1: Potential for New Targeted Treatment Strategies in Succinate Dehydrogenase Deficient Paragangliomas

Frontiers in Endocrinology, 2021
Paragangliomas and pheochromocytomas (PPGLs) are chromaffin tumors associated with severe catecholamine-induced morbidities. Surgical removal is often curative.
Dieter M. Matlac, Katerina Hadrava Vanova, Nicole Bechmann, S. Richter, J. Folberth, H. Ghayee, Guangbo Ge, Luma Abunimer, R. Wesley, R. Aherrahrou, Margo Dona, Á. Martínez-Montes, Bruna Calsina, M. Merino, M. Schwaninger, P. Deen, Z. Zhuang, J. Neuzil, K. Pacak, H. Lehnert, S. Fliedner   +20 more
semanticscholar   +1 more source

Succinate Can Shuttle Reducing Power from the Hypoxic Retina to the O2-Rich Pigment Epithelium

Cell Reports, 2020
Summary: When O2 is plentiful, the mitochondrial electron transport chain uses it as a terminal electron acceptor. However, the mammalian retina thrives in a hypoxic niche in the eye.
Celia M. Bisbach, Daniel T. Hass, Brian M. Robbings, Austin M. Rountree, Martin Sadilek, Ian R. Sweet, James B. Hurley   +6 more
doaj   +1 more source

Succinic Dehydrogenase in Protozoa [PDF]

Nature, 1947
THERE is, as yet, relatively little information about the occurrence of individual enzymes in Protozoa. We have been successful in demonstrating the presence of a succinic dehydrogenase in homogenates of Paramecium caudatum. This has been done using a modified Cartesian diver respirometer of macro dimensions (40–60 µ1. total volume).
B A, HUMPHREY, G F, HUMPHREY
openaire   +2 more sources

The Effect of Initial Moisture Content, Packaging and Storage Period on Succinate Dehydrogenase and Cytochrome Oxidase Activity of Soybean Seed

Biotropia: The Southeast Asian Journal of Tropical Biology, 2010
The quality of soybean seed is easily decreased, so that it is difficult to keep them for a long time. The research aims to study the effect of initial moisture content, packaging material and storage period on succinate dehydrogenase and cytochrome ...
Aurellia Tatipata
doaj   +3 more sources

Functional and Biogenetical Heterogeneity of the Inner Membrane of Rat-Liver Mitochondria [PDF]

, 1971
Rat liver mitochondria were fragmented by a combined technique of swelling, shrinking, and sonication. Fragments of inner membrane were separated by density gradient centrifugation.
Allmann D. W., Ashwell M., Beattie D. S., Beattie D. S., Brunner G., Burstone M. S., Davis K. A., Delbruck A., Fiske C. H., Folch J., Gear A. R. L., Gear A. R. L., Gear A. R. L., Gelder B. F., Gotterer G. S., Hasegawa E., Hawley E. S., Johnson A. B., Klingenberg M., Kuntzel H., Labbe R. F., Lentz P. E., Neupert W., Neupert W., Novikoff A. B., Ohnishi K., Omura T., Parsons D. F., Parsons D. F., Pette D., Pollak J. K., Pullmann M. E., Raw J., Raw J., Reith A., Schneider W. C., Schuel H., Schumacher H.-H., Sebald W., Sebald W., Seligman A. M., Sies H., Sottocasa G. L., Stoffel W., Strecker H. J., Swick R. W., Szarkowska L., Tabor C. W., Tol A., Vazquez J. J., Yonetani T.   +50 more
core   +1 more source

Succinate Dehydrogenase Deficiency

Archives of Pathology & Laboratory Medicine, 2000
Abstract Background.—Partial succinate dehydrogenase deficiency (15% to 50% of normal reference enzyme activity) in skeletal muscle causes mitochondrial myopathy with various symptoms, for example, brain involvement, cardiomyopathy, and/or exercise intolerance.
G D, Vladutiu, R R, Heffner
openaire   +2 more sources

Treatment responses to antiangiogenetic therapy and chemotherapy in nonsecreting paraganglioma (PGL4) of urinary bladder with SDHB mutation: a case report [PDF]

, 2018
Paraganglioma (PGL) is a rare neuroendocrine tumor. Currently, the malignancy is defined as the presence of metastatic spread at presentation or during follow-up.
Aschelter, Am, Capriotti, G, Cerquetti, L, Lardo, P, Marchetti, P, Matarazzo, I, Nardone, Mr, Petrangeli, E, Schiavi, F, Stigliano, A, Toscano, V   +10 more
core   +1 more source

Itaconate and Its Derivatives Repress Early Myogenesis In Vitro and In Vivo

Frontiers in Immunology, 2022
A Krebs cycle intermediate metabolite, itaconate, has gained attention as a potential antimicrobial and autoimmune disease treatment due to its anti-inflammatory effects.
Tae Seok Oh, Damian C. Hutchins, Rabina Mainali, Kevin H. Goslen, Matthew A. Quinn, Matthew A. Quinn   +5 more
doaj   +1 more source

Transcriptional analysis of pqqD and study of the regulation of pyrroloquinoline quinone biosynthesis in Methylobacterium extorquens AM1 [PDF]

, 1995
Methanol dehydrogenase, the enzyme that oxidizes methanol to formaldehyde in gram-negative methylotrophs, contains the prosthetic group pyrroloquinoline quinone (PQQ).
Lidstrom, Mary E., Ramamoorthi, Roopa
core   +2 more sources