Results 81 to 90 of about 3,361 (281)

Succinate aggravates pulmonary fibrosis through the succinate/SUCNR1 axis

American Journal of Physiology-Lung Cellular and Molecular Physiology
This paper highlights the role of the succinate/SUCNR1 axis in pulmonary fibrosis. Receptor activation leads to profibrotic changes in IPF patient-derived fibroblasts. This finding could also be replicated in a mouse model of pulmonary fibrosis.
Rishi Rajesh, Agnes Anna Mooslechner, Hannah Schweighofer, Svetlana Pahernik, Ilse Lanz, Reham Atallah, Wolfgang Platzer, Clemens Aigner, Alberto Benazzo, Stefano Angiari, Leigh Marsh, Grazyna Kwapiszewska, Akos Heinemann, Thomas Bärnthaler   +13 more
openaire   +2 more sources

Techno‐Economic Analysis of Polylactic Acid from Corn Stover: Understanding Uncertainty and Variability via Artificial Intelligence Tools

Advanced Sustainable Systems, EarlyView.
This study analyses the uncertainty and variability existing in the economic performance of polylactic acid (PLA) production, via integrating techno‐economic analysis with process models and Monte Carlo simulation enabled by artificial intelligence. The results show that the minimum selling price varies from $2,107 to $3076/t PLA.
Yinqiao Wang, Jiawei Huang, Chuan Xu, Sipan Liu, Junwei Li, Kai Lan   +5 more
wiley   +1 more source

Effect of succinic acid on the organism of mice and their intestinal microbiota against the background of excessive fat consumption

Regulatory Mechanisms in Biosystems, 2020
Succinic acid and its salts (succinates) positively affect the oxygenation of the internal environment, stabilize the structure and functional activity of mitochondria, and normalize the ion metabolism in the cell.
M. A. Lieshchova, M. V. Bilan, A. A. Bohomaz, N. M. Tishkina, V. V. Brygadyrenko   +4 more
doaj   +1 more source

Természetben előforduló és mesterséges karotinoidok izolálása, előállítása, szerkezetigazolása = Isolation and structure elucidation of natural and semisynthetic carotenoids [PDF]

, 2010
Kereskedelmi szilikagél lúgos kezelésével olyan nagy kapacitású preparatív kromatográfiás állófázist állítottunk elő, amely az igen savérzékeny karotinoid-5,6-epoxidok elválasztására is alkalmas.
Agócs, Attila, Deli, József, Matus, Zoltán, Molnár, Péter, Nagy, Veronika, Szabó, Zoltán, Tóth, Gyula   +6 more
core  

Ecosystem‐Centered Robot Design: Toward Ecoresorbable Sustainability Robots (ESRs)

Advanced Science, EarlyView.
Robots exploring natural ecosystems can support monitoring and conservation, but must adopt ecosystem‐centered design to avoid pollution, waste, and damage. This review proposes guidelines for co‐designing ecoresorbable sustainability robots (ESRs), uniting materials, robotics, and ecological contexts in a single framework.
Tülin Yılmaz Nayır, Yuan Fang, Consuelo Contreras, Andrew K. Schulz, Florian Hartmann   +4 more
wiley   +1 more source

Proteogenomic characterization of cholangiocarcinoma

Hepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng, Peng Ran, Lingli Chen, Yunzhi Wang, Zixiang Yu, Ke Cai, Jinwen Feng, Zhaoyu Qin, Yanan Yin, Subei Tan, Yang Liu, Chen Xu, Guoming Shi, Yuan Ji, Jian‐Yuan Zhao, Jian Zhou, Jia Fan, Yingyong Hou, Chen Ding   +18 more
wiley   +1 more source

Ionic Liquid as Reaction Media for the Production of Cellulose-Derived Polymers from Cellulosic Biomass

ChemEngineering, 2017
The most frequent polymer on nature is cellulose that is present together with lignin and hemicellulose in vegetal biomass. Cellulose can be, in the future, sustainable raw matter for chemicals, fuels, and materials.
Joana Maria Lopes, María Dolores Bermejo, Ángel Martín, María José Cocero   +3 more
doaj   +1 more source

Application of electrical stimulation for functional tissue engineering in vitro and in vivo [PDF]

, 2013
The present invention provides new methods for the in vitro preparation of bioartificial tissue equivalents and their enhanced integration after implantation in vivo.
Freed, Lisa, Langer, Robert, Park, Hyoungshin, Radisic, Milica, Vunjak-Novakovic, Gordana   +4 more
core   +1 more source

One-pot synthesis of 2,3-bis-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)succinates and arylmethylene-bis-3,3-quinoline-2-ones [PDF]

, 2019
In this investigation an efficient synthesis of 2,3-bis-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)succinic acid derivatives was achieved by one-pot reaction of one equivalent of aromatic amines with two equivalents of diethyl malonate in diphenyl ether ...
Aly, Ashraf A., Bakheet, Momtaz E. M., Bräse, Stefan, El-Sheref, Essmat M., Mourad, Aboul-Fetouh E., Nieger, Martin   +5 more
core   +1 more source

Catalytic Methods in Flow Chemistry [PDF]

, 2020
The chemical industry is essential in the daily humn life of modern society; despite the misconception about the real need for chemical production, everyone enjoys the benefit of the chemical progress.
Len, Christophe, Luisi, Renzo
core   +1 more source