Results 81 to 90 of about 3,444 (280)

Automated Bacterial Identification and Morphological Feature Analysis in Low‐Dose Cryo‐EM Using YOLOv11

Advanced Intelligent Discovery, EarlyView.
AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula, Lynnicia N. Massenburg, Spenser R. Brown, Amber N. Bible, Chanda R. Harris, Lance X. Zhang, Kiara Parker, Scott T. Retterer, Jennifer L. Morrell‐Falvey, Rama K. Vasudevan, Alexis N. Williams   +10 more
wiley   +1 more source

Success of Succinates and Prospects for Their Use in Critical Conditions

Антибиотики и Химиотерапия
To date, preparations containing succinic acid (succinate) are widely known to specialists working in intensive care. Several such preparations have gained wide acclaim among anesthesiologists and resuscitators, namely: Reamberin, infusion solution — a ...
S. V. Sviridov, A. V. Butrov, V. V. Afanasyev, Yu. P. Orlov, A. Yu. Petrov   +4 more
doaj   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

Effect of succinic acid on the organism of mice and their intestinal microbiota against the background of excessive fat consumption

Regulatory Mechanisms in Biosystems, 2020
Succinic acid and its salts (succinates) positively affect the oxygenation of the internal environment, stabilize the structure and functional activity of mitochondria, and normalize the ion metabolism in the cell.
M. A. Lieshchova, M. V. Bilan, A. A. Bohomaz, N. M. Tishkina, V. V. Brygadyrenko   +4 more
doaj   +1 more source

Succinate aggravates pulmonary fibrosis through the succinate/SUCNR1 axis

American Journal of Physiology-Lung Cellular and Molecular Physiology
This paper highlights the role of the succinate/SUCNR1 axis in pulmonary fibrosis. Receptor activation leads to profibrotic changes in IPF patient-derived fibroblasts. This finding could also be replicated in a mouse model of pulmonary fibrosis.
Rishi Rajesh, Agnes Anna Mooslechner, Hannah Schweighofer, Svetlana Pahernik, Ilse Lanz, Reham Atallah, Wolfgang Platzer, Clemens Aigner, Alberto Benazzo, Stefano Angiari, Leigh Marsh, Grazyna Kwapiszewska, Akos Heinemann, Thomas Bärnthaler   +13 more
openaire   +2 more sources

Effects of intermittent exposure to hypobaria and cold on the microarchitecture and morphofunctional profile of rat gastrocnemius muscle

The Anatomical Record, EarlyView.
Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes, Teresa Pagès, Ginés Viscor, Joan Ramon Torrella   +3 more
wiley   +1 more source

Ionic Liquid as Reaction Media for the Production of Cellulose-Derived Polymers from Cellulosic Biomass

ChemEngineering, 2017
The most frequent polymer on nature is cellulose that is present together with lignin and hemicellulose in vegetal biomass. Cellulose can be, in the future, sustainable raw matter for chemicals, fuels, and materials.
Joana Maria Lopes, María Dolores Bermejo, Ángel Martín, María José Cocero   +3 more
doaj   +1 more source

Természetben előforduló és mesterséges karotinoidok izolálása, előállítása, szerkezetigazolása = Isolation and structure elucidation of natural and semisynthetic carotenoids [PDF]

, 2010
Kereskedelmi szilikagél lúgos kezelésével olyan nagy kapacitású preparatív kromatográfiás állófázist állítottunk elő, amely az igen savérzékeny karotinoid-5,6-epoxidok elválasztására is alkalmas.
Agócs, Attila, Deli, József, Matus, Zoltán, Molnár, Péter, Nagy, Veronika, Szabó, Zoltán, Tóth, Gyula   +6 more
core  

Dietary Glutamine Supplementation Alleviated Rumen Epithelium Oxidative Damage and Apoptosis Induced by Feed Restriction via Maintaining Mitochondrial Homeostasis in Female Yaks

Animal Research and One Health, EarlyView.
Dietary glutamine (Gln) supplementation increased the ATP levels and promoted cell proliferation in the rumen epithelium of feed‐restricted yaks. Besides, Gln inhibited ROS accumulation and reduced oxidative damage and apoptosis in the rumen epithelium of feed‐restricted yaks.
Ziqi Yue, Shanpeng Ke, Liyuan Shi, Rui Hu, Zhisheng Wang, Quanhui Peng, Huawei Zou, Jianxin Xiao, Yahui Jiang, Fali Wu, Yiping Tang   +10 more
wiley   +1 more source

Attachment of Nucleosides to Solid‐Phase Supports [PDF]

, 2000
Specific step‐by‐step instructions are given for coupling nucleosides to LCAA‐CPG supports (supports consisting of a long‐chain alkylamine linked to controlled‐pore glass).
Horn M., Pon R.T., Pon R.T.
core   +1 more source