Results 1 to 10 of about 21,364 (252)

Assessment of the Teratogenic Effect of Sulfadoxine-Pyrimethamine on the Chicken Embryo

Journal of Toxicology, 2022
Background. The sulfadoxine-pyrimethamine combination is a product used in the intermittent preventive treatment (IPT) of malaria in pregnant women in our country. To date, there is very little data on the teratogenic effect of this product.
Rachida Moussa Tari, Aboudoulatif Diallo, Emmanuelle Kouame, Phénix Assogba, Essotolom Badjabaissi, Lawson-Evi Povi, Batomayena Bakoma, Yao Potchoo, Kokou Tona   +8 more
doaj   +2 more sources

Differentials in prevalence and correlates on uptake of tetanus toxoid and intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy: A community-based cross-sectional study in The Gambia

SAGE Open Medicine, 2022
Objectives: The study examined the differentials in prevalence and correlates on the uptake of tetanus toxoid and intermittent preventive treatment of malaria among pregnant women in The Gambia.
Amadou Barrow, Sulayman Barrow, Amienatta Jobe   +2 more
doaj   +2 more sources

Nationwide Monitoring for Plasmodium falciparum Drug-Resistance Alleles to Chloroquine, Sulfadoxine, and Pyrimethamine, Haiti, 2016–2017

Emerging Infectious Diseases, 2020
Haiti is striving for zero local malaria transmission by the year 2025. Chloroquine remains the first-line treatment, and sulfadoxine/pyrimethamine (SP) has been used for mass drug-administration pilot programs.
Eric Rogier, Camelia Herman, Curtis S. Huber, Karen E.S. Hamre, Baby Pierre, Kimberly E. Mace, Jacquelin Présumé, Gina Mondélus, Ithamare Romilus, Tamara Elismé, Thomas P. Eisele, Thomas Druetz, Alexandre Existe, Jacques Boncy, Jean F. Lemoine, Venkatachalam Udhayakumar, Michelle A. Chang   +16 more
doaj   +2 more sources

Effects of maternal antenatal treatment with two doses of azithromycin added to monthly sulfadoxine-pyrimethamine for the prevention of low birth weight in Burkina Faso: an open-label randomized controlled trial

Malaria Journal, 2023
Background Exposure during pregnancy to malaria and sexually-transmitted infections is associated with adverse birth outcomes including low birth weight (LBW).
Moussa Lingani, Serge H. Zango, Innocent Valéa, Sékou Samadoulougou, Georges Somé, Maïmouna Sanou, Berenger Kaboré, Toussaint Rouamba, Herman Sorgho, Marc C. Tahita, Karim Derra, Michèle Dramaix, Halidou Tinto, Philippe Donnen, Annie Robert   +14 more
doaj   +2 more sources

Stable high frequencies of sulfadoxine–pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine–pyrimethamine in Ujjain, Madhya Pradesh, India

Malaria Journal, 2020
Background Artesunate plus sulfadoxine–pyrimethamine (ASP) is first-line treatment for uncomplicated Plasmodium falciparum malaria in most of India, except for six North-eastern provinces where treatment failure rates were high. In Ujjain, central India,
Ashish Pathak, Andreas Mårtensson, Sudhir Gawariker, Ashish Sharma, Vishal Diwan, Manju Purohit, Johan Ursing   +6 more
doaj   +2 more sources

Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2004
In vivo antimalarial drug efficacy studies of uncomplicated Plasmodium falciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of ...
Alan J. Magill, Jorge Zegarra, Coralith Garcia, Wilmer Marquiño, Trenton K. Ruebush II   +4 more
doaj   +2 more sources

Country wide surveillance reveals prevalent artemisinin partial resistance mutations with evidence for multiple origins and expansion of high level sulfadoxine-pyrimethamine resistance mutations in northwest Tanzania

medRxiv, 2023
Background: Emergence of artemisinin partial resistance (ArtR) in Plasmodium falciparum in East Africa is a growing threat to the efficacy of artemisinin combination therapies (ACT) and the global efforts for malaria elimination.
J. Juliano, D. Giesbrecht, A. Simkin, A. Fola, B. Lyimo, D. Perus, C. Bakari, R. Madebe, M. D. Seth, C. Mandara, Z. R. Popkin-Hall, R. Moshi, R. B. Mbwambo, K. Niaré, B. MacInnis, F. Francis, D. Mbwambo, I. Garimo, Frank Chacky, S. Aaron, A. Lusasi, F. Molteni, R. Njau, S. Lazaro, A. Mohamed, J. Bailey, D. Ishengoma   +26 more
semanticscholar   +1 more source

Spatiotemporal spread of Plasmodium falciparum mutations for resistance to sulfadoxine-pyrimethamine across Africa, 1990–2020

PLoS Comput. Biol., 2022
Background Sulfadoxine-pyrimethamine (SP) is recommended in Africa in several antimalarial preventive regimens including Intermittent Preventive Treatment in pregnant women (IPTp), Intermittent Preventive Treatment in infants (IPTi) and Seasonal Malaria ...
J. Flegg, Georgina S. Humphreys, Brenda Montanez, Taryn Strickland, Zaira J Jacome-Meza, K. Barnes, J. Raman, P. Guérin, C. Sibley, S. D. Otienoburu   +9 more
semanticscholar   +1 more source

Efficacy of Corticosteroids and Intravenous Immunoglobulins in a Patient with Toxic Epidermal Necrolysis Secondary to Sulfadoxine: A Case Report and Literature Review

Reports, 2023
Toxic epidermal necrolysis (TEN) is a rare life-threatening mucocutaneous reaction characterized by epidermal detachment. Treatment success relies on early diagnosis, rapid withdrawal of the causative drug and supportive care.
Alba Escolà-Rodríguez, Ángel Marcos-Fendian, Carla Bastida, Javier Gil Lianes, Pedro Castro, José Manuel Mascaró, Dolors Soy Muner   +6 more
doaj   +1 more source

Molecular Markers for Sulfadoxine/Pyrimethamine and Chloroquine Resistance in Plasmodium falciparum in Thailand

Korean Journal of Parasitology, 2022
Drug resistance is an important problem hindering malaria elimination in tropical areas. Point mutations in Plasmodium falciparum dihydrofolate reductase (Pfdhfr) and dihydropteroate synthase (Pfdhps) genes confer resistance to antifolate drug ...
Jiraporn Kuesap, Nutnicha Suphakhonchuwong, Lertluk Kalawong, Natthaya Khumchum   +3 more
semanticscholar   +1 more source