Results 51 to 60 of about 14,994 (217)

Effects of Drug Resistance on the Global Spread of Malaria: A Systematic Literature Review

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Malaria remains a major health crisis in tropical regions, with Sub‐Saharan Africa bearing the heaviest burden. While insecticide‐treated nets and artemisinin‐based combination therapies (ACTs) have reduced cases, emerging parasite resistance to artemisinin threatens these gains. This review synthesizes evidence on how drug
Ashenafi Woldemichael Woime
wiley   +1 more source

High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581. [PDF]

, 2009
BACKGROUND: Sulphadoxine-pyrimethamine (SP) a widely used treatment for uncomplicated malaria and recommended for intermittent preventive treatment of malaria in pregnancy, is being investigated for intermittent preventive treatment of malaria in infants
Gesase Samwel, Daniel Chandramohan, Mosha Jacklin F., Mandia, Victor, Joho, Angel, Victor Mandia, Martha Lemnge, Greenwood, Brian, Samwel Gesase, Gesase, Samwel, Chandramohan Daniel, Mosha Frank W., Savael, Zacharia, Ord, Rosalynn, Roper, Cally, Angel Joho, Madebe, Rashid, Greenwood Brian, Hashim Ramadhan, Frank W. Mosha, Mrema Hedwiga, Inbarani Naidoo, Chandramohan, Daniel, Zacharia Savael, Mapunda Ephraim, Mosha, Frank W, Lemnge Martha, Madebe Rashid, Rosalynn Ord, Mapunda, Ephraim, Ephraim Mapunda, Roly D Gosling, Naidoo Inbarani, Frank W Mosha, Hashim, Ramadhan, Cally Roper, Mandia Victor, Gosling, Roly D, Victor M, Jacklin F. Mosha, Gosling Roly D., Lemnge, Martha, Ord Rosalynn, Hedwiga Mrema, Brian Greenwood, Mrema, Hedwiga, Roly D. Gosling, Roper Cally, Jacklin F Mosha, Ramadhan Hashim, Rashid Madebe, Mosha, Jacklin F, Naidoo, Inbarani, Savael Zacharia, Joho Angel   +54 more
core   +2 more sources

Independent Lineages of Highly Sulfadoxine-Resistant Plasmodium falciparum Haplotypes, Eastern Africa

Emerging Infectious Diseases, 2014
Sulfadoxine-resistant Plasmodium falciparum undermines malaria prevention with sulfadoxine/pyrimethamine. Parasites with a highly resistant mutant dihydropteroate synthase (dhps) haplotype have recently emerged in eastern Africa; they negated preventive ...
Steve M. Taylor, Alejandro L. Antonia, Whitney E. Harrington, Morgan M. Goheen, Victor Mwapasa, Ebbie Chaluluka, Michal Fried, Edward Kabyemela, Mwayi Madanitsa, Carole Khairallah, Linda Kalilani-Phiri, Antoinette K. Tshefu, Stephen J. Rogerson, Feiko O. ter Kuile, Patrick E. Duffy, Steven R. Meshnick   +15 more
doaj   +1 more source

Nationwide Monitoring for Plasmodium falciparum Drug-Resistance Alleles to Chloroquine, Sulfadoxine, and Pyrimethamine, Haiti, 2016–2017

Emerging Infectious Diseases, 2020
Haiti is striving for zero local malaria transmission by the year 2025. Chloroquine remains the first-line treatment, and sulfadoxine/pyrimethamine (SP) has been used for mass drug-administration pilot programs.
Eric Rogier, Camelia Herman, Curtis S. Huber, Karen E.S. Hamre, Baby Pierre, Kimberly E. Mace, Jacquelin Présumé, Gina Mondélus, Ithamare Romilus, Tamara Elismé, Thomas P. Eisele, Thomas Druetz, Alexandre Existe, Jacques Boncy, Jean F. Lemoine, Venkatachalam Udhayakumar, Michelle A. Chang   +16 more
doaj   +1 more source

Effect of intramuscular sulfadoxine-pyrimethamine on pregnant Wistar rats [PDF]

The Anatomical Record, 1998
Sulfadoxine-pyrimethamine preparations are used commonly for the treatment and or prevention of malaria in the endemic regions of Sub-Sahara Africa. Pyrimethamine alone has been shown to be teratogenic in rats, mice and hamsters, and others animals.Pregnant Wistar rats were divided into three groups.
openaire   +2 more sources

Safety of Prenatal Anti‐Infective Use and Offspring Outcomes: A Panoramic Assessment by Indication, Drug Class, and Exposure Characteristics

iMetaMed, Volume 2, Issue 3, September 2026.
Based on the comprehensive, panoramic assessment of the safety of prenatal anti‐infective use across indications, drug classes, and exposure characteristics, potential safety signals associated with prenatal exposure to several widely used anti‐infective drug classes were identified, including macrolides, metronidazole, tetracyclines, sulfonamides ...
Wenling Wang, Yuezhen Li, Chunrong Liu, Chen Chen, Meng Chen, Lehana Thabane, Xin Sun, Jing Tan   +7 more
wiley   +1 more source

Five years of antimalarial resistance marker surveillance in Gaza Province, Mozambique, following artemisinin-based combination therapy roll out. [PDF]

PLoS ONE, 2011
Antimalarial drug resistance is a major obstacle to malaria control and eventual elimination. The routine surveillance for molecular marker of resistance is an efficient way to assess drug efficacy, which remains feasible in areas where malaria control ...
Jaishree Raman, Katya Mauff, Pedro Muianga, Abdul Mussa, Rajendra Maharaj, Karen I Barnes   +5 more
doaj   +1 more source

Assessment of Nutritional and Nonnutritional Correlates of Anemia in Pregnancy: A Hospital‐Based Cross‐Sectional Study for Public Health Interventions in the Bono East Region of Ghana

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Anemia in pregnancy (AiP) remains a public health concern in Ghana. The Bono East Region is known for a variety of maternal morbidities, yet the association between inadequate intake of iron‐rich foods and AiP remains underexplored.
Dennis Bardoe, Joana Apenkwa, Daniel Hayford, Ernest Osei, Robert Bagngmen Bio, Salma Bardoe Ahmed   +5 more
wiley   +1 more source

A randomized controlled pilot trial of azithromycin or artesunate added to sulfadoxine-pyrimethamine as treatment for malaria in pregnant women. [PDF]

PLoS ONE, 2007
New anti-malarial regimens are urgently needed in sub-Saharan Africa because of the increase in drug resistance. We investigated the safety and efficacy of azithromycin or artesunate combined with sulfadoxine-pyrimethamine used for treatment of malaria ...
Linda Kalilani, Innocent Mofolo, Marjorie Chaponda, Stephen J Rogerson, Alisa P Alker, Jesse J Kwiek, Steven R Meshnick   +6 more
doaj   +1 more source

Pre‐Eclampsia and Its Associated Factors Among Pregnant Women in Ghana: A Retrospective Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Pre‐eclampsia remains a major cause of feto‐maternal death in Ghana, with a rising incidence linked to multiple factors that hinder prevention. Despite it's impact, few studies have explored associated risks. This study assessed the prevalence, risk factors, and maternal–neonatal outcomes associated with pre‐eclampsia among
Sabastian Adjei, Wilfred Sam‐Awortwi Jnr, Richmond Adu Boahen Boamah, Edward Osei Gyimah, William Kweku Payne, Harriet Yeboaa Diawuo, Samuel Kwame Sopuruchi Agomuo, Oscar Simon Olympio Mensah, Alfred Effah, Christian Obirikorang   +9 more
wiley   +1 more source