Results 61 to 70 of about 14,994 (217)

Monitoring for multidrug-resistant Plasmodium falciparum isolates and analysis of pyrimethamine resistance evolution in Uige province, Angola.

, 2009
OBJECTIVES: To assess the extent of drug resistance in Uige through molecular genetic analysis and to test whether the dhfr triple mutant alleles present in Angola are of southeast Asian origin.
Inojosa WO, Roper C, Bisoffi, Zeno, Bisoffi Z, Ord, Rosalynn, Roper, Cally, Abel PM, Severini C, Pisani, Vincenzo, Matondo A, Warhurst DC, Pisani V, Pearce RJ, Matondo, Alexandre, Warhurst, David C, Severini, Carlo, Menegon M, Menegon, Michela, Inojosa, Walter O, Abel, Paulo M, Majori, Giancarlo, Majori G, Ord R, Pearce, Richard J   +23 more
core   +1 more source

Comparative Evaluation of the Dynamics of Parameters of Cell-Mediated Immunity under the Influence of Different Therapies for Chronic Acquired Toxoplasmosis

Aktualʹnaâ Infektologiâ, 2015
The article presents a comparative evaluation of the dynamics of parameters of cell-mediated immunity in patients under the influence of different therapies for chronic acquired toxoplasmosis (CAT).
O.V. Bobrova, Anuar al Hatib
doaj   +1 more source

Discovery of Potent Antimalarial Agents Targeting Plasmodium falciparum DNA Gyrase B by Integrating Computational and Experimental Approaches

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
An integrated computational and experimental drug‐discovery approach identified UNC8153 as a potential novel scaffold active against drug‐sensitive and artemisinin‐resistant P. falciparum strains through inhibition of apicoplast PfGyrB. ABSTRACT The global spread of drug‐resistant Plasmodium falciparum, particularly artemisinin‐resistant strains ...
Biswajit Naik, Welka Sahu, Guneswar Sethi, Cherish Prashar, Gajendra Mohan Baldodiya, Jyoti Poswal, Chandi C. Mandal, Jeong Ho Hwang, Kailash C. Panday, K. Sony Reddy, Dhaneswar Prusty   +10 more
wiley   +1 more source

Short report: molecular markers associated with Plasmodium falciparum resistance to sulfadoxine-pyrimethamine in the Democratic Republic of Congo. [PDF]

, 2006
Sulfadoxine-pyrimethamine (SP) is the first line antimalarial treatment in the Democratic Republic of Congo. Using polymerase chain reaction, we assessed the prevalence of mutations in the dihydrofolate reductase (dhfr) (codons 108, 51, 59) and ...
Guthmann, J P, Bonnet, M, Cohuet, S, Van Herp, M, D'Alessandro, U, Van Overmeir, C, Guthmann, J P P   +6 more
core  

Intermittent preventive therapy for malaria: progress and future directions.

, 2007
PURPOSE OF REVIEW: This review summarizes recent evidence regarding the efficacy of intermittent preventive treatment with focus on infancy (IPTi) and the rationale behind such a control strategy.
Grobusch, Martin P., Gosling, Roly D., Newman, Robert D., Grobusch, Martin P, Gosling, Roly D, Egan, Andrea, Newman, Robert D   +6 more
core   +1 more source

Understanding Opportunity Costs of Women Participating in Maternal and Child Nutrition Interventions in Southern Angola: Evidence From the MuCCUA Trial

Maternal &Child Nutrition, Volume 22, Issue 3, July 2026.
Economic evaluations of multisectoral nutrition interventions often overlook participants' costs. Using MuCCUA trial data, we estimated women's opportunity costs of three maternal and child nutrition interventions in Angola. Remote participants faced burdens equivalent to 1–1.5 workdays monthly.
Rocio Martin‐Cañavate, Antonio Pujol‐de Castro, Chloe Puett, Elena Trigo, Maria de Lourdes Faria, Ana Silva Gerardo, Antonio Vargas, Israel Molina, Estefania Custodio   +8 more
wiley   +1 more source

Molecular monitoring of resistant dhfr and dhps allelic haplotypes in Morogoro and Mvomero districts in south eastern Tanzania. [PDF]

, 2011
BACKGROUND\ud \ud Resistance to the antimalarial drug sulfadoxine-pyrimethamine (SP) emerged in Plasmodium falciparum from Asia in the 1960s and subsequently spread to Africa.
Abdullah, S, Kachur, P, Roper, C., Bloland, P., Pearce, R., Pearce, R, Mshinda, H, Mshinda, H., Malisa, A, Mutayoba, B, Roper, C, Abdullah, S., Kachur, P., Malisa, A., Mutayoba, B., Bloland, P   +15 more
core   +1 more source

Determinants of Low Birth Weight in Ghana: Analysis of the 2022 Demographic and Health Survey

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Low birth weight (LBW) remains a significant public health challenge in developing countries, contributing substantially to infant mortality and morbidity. Objective To examine sociodemographic, maternal health, and healthcare utilization factors associated with low birth weight in Ghana.
Michael Arthur Ofori, David Kwamena Mensah, Theophilus Asamoah, Michael Fosu Ofori   +3 more
wiley   +1 more source

Diagnosis and treatment of endoparasites in pet rabbits

In Practice, Volume 48, Issue 5, Page 258-265, June 2026.
Background: Rabbits are popular pets and members of the veterinary team play a critical role both as providers of species‐specific medical care and a source of informed advice regarding husbandry and preventive medicine. Rabbits can potentially be infected with a somewhat bewildering array of endoparasites, but pathogenicity and significance of ...
Kate Hughes, Richard Saunders
wiley   +1 more source

Intermittent preventive treatment for malaria in pregnancy in Africa: what's new, what's needed? [PDF]

, 2007
Falciparum malaria is an important cause of maternal, perinatal and neonatal morbidity in high transmission settings in Sub-Saharan Africa. Intermittent preventive treatment with sulphadoxine-pyrimethamine (SP-IPT) has proven efficacious in reducing the ...
Vallely, Andrew, Changalucha, John, Daniel Chandramohan, Greenwood Brian, John Changalucha, Vallely Andrew, Lisa Vallely, Vallely Lisa, Chandramohan, Daniel, Changalucha John, Greenwood, Brian, Brian Greenwood, Vallely, Lisa, Andrew Vallely, Chandramohan Daniel   +14 more
core   +1 more source