Results 11 to 20 of about 20,006 (291)

Differentials in prevalence and correlates on uptake of tetanus toxoid and intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy: A community-based cross-sectional study in The Gambia

SAGE Open Medicine, 2022
Objectives: The study examined the differentials in prevalence and correlates on the uptake of tetanus toxoid and intermittent preventive treatment of malaria among pregnant women in The Gambia.
Amadou Barrow, Sulayman Barrow, Amienatta Jobe   +2 more
doaj   +2 more sources

Nationwide Monitoring for Plasmodium falciparum Drug-Resistance Alleles to Chloroquine, Sulfadoxine, and Pyrimethamine, Haiti, 2016–2017

Emerging Infectious Diseases, 2020
Haiti is striving for zero local malaria transmission by the year 2025. Chloroquine remains the first-line treatment, and sulfadoxine/pyrimethamine (SP) has been used for mass drug-administration pilot programs.
Eric Rogier, Camelia Herman, Curtis S. Huber, Karen E.S. Hamre, Baby Pierre, Kimberly E. Mace, Jacquelin Présumé, Gina Mondélus, Ithamare Romilus, Tamara Elismé, Thomas P. Eisele, Thomas Druetz, Alexandre Existe, Jacques Boncy, Jean F. Lemoine, Venkatachalam Udhayakumar, Michelle A. Chang   +16 more
doaj   +2 more sources

Stable high frequencies of sulfadoxine–pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine–pyrimethamine in Ujjain, Madhya Pradesh, India

Malaria Journal, 2020
Background Artesunate plus sulfadoxine–pyrimethamine (ASP) is first-line treatment for uncomplicated Plasmodium falciparum malaria in most of India, except for six North-eastern provinces where treatment failure rates were high. In Ujjain, central India,
Ashish Pathak, Andreas Mårtensson, Sudhir Gawariker, Ashish Sharma, Vishal Diwan, Manju Purohit, Johan Ursing   +6 more
doaj   +2 more sources

Effect of intramuscular sulfadoxine-pyrimethamine on pregnant Wistar rats [PDF]

The Anatomical Record, 1998
Sulfadoxine-pyrimethamine preparations are used commonly for the treatment and or prevention of malaria in the endemic regions of Sub-Sahara Africa. Pyrimethamine alone has been shown to be teratogenic in rats, mice and hamsters, and others animals.Pregnant Wistar rats were divided into three groups.
E.O. Uche‐Nwachi
openaire   +3 more sources

Evolution of Resistance to Sulfadoxine-Pyrimethamine in Plasmodium falciparum [PDF]

Antimicrobial Agents and Chemotherapy, 2004
ABSTRACT The development of resistance to sulfadoxine-pyrimethamine by Plasmodium parasites is a major problem for the effective treatment of malaria, especially P. falciparum malaria.
Michelle L. Gatton, Michelle L. Gatton, Qin Cheng, Laura B. Martin, Laura B. Martin   +4 more
openaire   +6 more sources

Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2004
In vivo antimalarial drug efficacy studies of uncomplicated Plasmodium falciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of ...
Alan J. Magill, Jorge Zegarra, Coralith Garcia, Wilmer Marquiño, Trenton K. Ruebush II   +4 more
doaj   +2 more sources

SULFADOXINE-PYRIMETHAMINE PLUS CHLOROQUINE OR AMODIAQUINE FOR UNCOMPLICATED FALCIPARUM MALARIA: A RANDOMIZED, MULTISITE TRIAL TO GUIDE NATIONAL POLICY IN UGANDA [PDF]

, 2005
The use of combinations of inexpensive drugs for the treatment of malaria in Africa has been proposed as an interim policy while awaiting the widespread availability of more effective regimens.
Nathan Bakyaita, Grant Dorsey, Adoke Yeka, Kristin Banek, Sarah G. Staedke, Moses R. Kamya, Ambrose Talisuna, Fred Kironde, Samuel L. Nsobya, A. H. D. Kilian, Arthur Reingold, Philip J. Rosenthal, Fred Wabwire‐Mangen   +12 more
openalex   +4 more sources

Therapeutic efficacy of chloroquine and sulfadoxine/pyrimethamine against Plasmodium falciparum infection in Somalia [PDF]

Bulletin of the World Health Organization, 2002
OBJECTIVE: To assess the efficacy of chloroquine and sulfadoxine/pyrimethamine in the treatment of uncomplicated Plasmodium falciparum infections in Somalia.
Warsame M., Abdillahi A., Duale O. Nur, Ismail A. Nur, Hassan A. M., Mohamed A., Warsame A.   +6 more
doaj   +3 more sources

Country wide surveillance reveals prevalent artemisinin partial resistance mutations with evidence for multiple origins and expansion of high level sulfadoxine-pyrimethamine resistance mutations in northwest Tanzania

medRxiv, 2023
Background: Emergence of artemisinin partial resistance (ArtR) in Plasmodium falciparum in East Africa is a growing threat to the efficacy of artemisinin combination therapies (ACT) and the global efforts for malaria elimination.
J. Juliano, D. Giesbrecht, A. Simkin, A. Fola, B. Lyimo, D. Perus, C. Bakari, R. Madebe, M. D. Seth, C. Mandara, Z. R. Popkin-Hall, R. Moshi, R. B. Mbwambo, K. Niaré, B. MacInnis, F. Francis, D. Mbwambo, I. Garimo, Frank Chacky, S. Aaron, A. Lusasi, F. Molteni, R. Njau, S. Lazaro, A. Mohamed, J. Bailey, D. Ishengoma   +26 more
semanticscholar   +1 more source

Spatiotemporal spread of Plasmodium falciparum mutations for resistance to sulfadoxine-pyrimethamine across Africa, 1990–2020

PLoS Comput. Biol., 2022
Background Sulfadoxine-pyrimethamine (SP) is recommended in Africa in several antimalarial preventive regimens including Intermittent Preventive Treatment in pregnant women (IPTp), Intermittent Preventive Treatment in infants (IPTi) and Seasonal Malaria ...
J. Flegg, Georgina S. Humphreys, Brenda Montanez, Taryn Strickland, Zaira J Jacome-Meza, K. Barnes, J. Raman, P. Guérin, C. Sibley, S. D. Otienoburu   +9 more
semanticscholar   +1 more source