Results 11 to 20 of about 10,197 (217)

A roadmap for understanding sulfadoxine-pyrimethamine in malaria chemoprevention. [PDF]

Parasitology
Sulfadoxine-pyrimethamine (SP) is the standard of care for Plasmodium falciparum malaria chemoprevention among pregnant women, infants, and children. However, SP’s antimalarial effectiveness is potentially threatened by resistant parasites. Developing alternative chemoprevention products and other prevention products, such as vaccines and monoclonal ...
Masserey T, Braunack-Mayer L, Miller RS, Möhrle JJ, Penny MA.   +4 more
europepmc   +4 more sources

A need for new tools for prevention of malaria in pregnancy. [PDF]

PLoS Medicine
Intermittent preventive treatment in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP) is a chemoprevention strategy against malaria in pregnancy. A recent PLOS Medicine study highlights the need for better understanding of the mechanism by which IPTp-
Makoto Saito, Rose McGready
doaj   +2 more sources

Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru [PDF]

Revista da Sociedade Brasileira de Medicina Tropical, 2004
In vivo antimalarial drug efficacy studies of uncomplicated Plasmodium falciparum malaria at an isolated site in the Amazon basin of Peru bordering Brazil and Colombia showed >50% RII/RIII resistance to sulfadoxine-pyrimethamine but no evidence of ...
Alan J. Magill, Jorge Zegarra, Coralith Garcia, Wilmer Marquiño, Trenton K. Ruebush II   +4 more
doaj   +2 more sources

Antimalarial drug sulfadoxine induces gametocytogenesis in Plasmodium berghei [PDF]

Malaria Journal
Background The spread of antimalarial drug resistance parasites is a major obstacle in eliminating malaria in endemic areas. This increases the urgency for developing novel antimalarial drugs with improved profiles to eliminate both sensitive and ...
Wihda Aisarul Azmi, Andita Fitri Mutiara Rizki, Achmad Shidiq, Yenny Djuardi, I Made Artika, Josephine Elizabeth Siregar   +5 more
doaj   +2 more sources

Efficacy of Corticosteroids and Intravenous Immunoglobulins in a Patient with Toxic Epidermal Necrolysis Secondary to Sulfadoxine: A Case Report and Literature Review

Reports, 2023
Toxic epidermal necrolysis (TEN) is a rare life-threatening mucocutaneous reaction characterized by epidermal detachment. Treatment success relies on early diagnosis, rapid withdrawal of the causative drug and supportive care.
Alba Escolà-Rodríguez, Ángel Marcos-Fendian, Carla Bastida, Javier Gil Lianes, Pedro Castro, José Manuel Mascaró, Dolors Soy Muner   +6 more
doaj   +1 more source

Genomic characterization of Plasmodium falciparum genes associated with anti-folate drug resistance and treatment outcomes in eastern India: A molecular surveillance study from 2008 to 2017

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionAfter being used vigorously for the previous two decades to treat P. falciparum, chloroquine and sulfadoxine-pyrimethamine were replaced in 2009 with an artemisinin-based combination therapy (artesunate-sulfadoxine-pyrimethamine) in an effort
Sabyasachi Das, Sabyasachi Das, Satyajit Tripathy, Ankita Das, Meenakshi Kumari Sharma, Ayan Nag, Amiya Kumar Hati, Somenath Roy   +7 more
doaj   +1 more source

Vulnerable newborn types: analysis of subnational, population‐based birth cohorts for 541 285 live births in 23 countries, 2000–2021

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView., 2023
Abstract Objective To examine prevalence of novel newborn types among 541 285 live births in 23 countries from 2000 to 2021. Design Descriptive multi‐country secondary data analysis. Setting Subnational, population‐based birth cohort studies (n = 45) in 23 low‐ and middle‐income countries (LMICs) spanning 2000–2021.
D. J. Erchick, E. A. Hazel, J. Katz, A. C. C. Lee, M. Diaz, L. S. F. Wu, S. Yoshida, R. Bahl, C. Grandi, A. B. Labrique, M. Rashid, S. Ahmed, A. D. Roy, R. Haque, S. Shaikh, A. H. Baqui, S. K. Saha, R. Khanam, S. Rahman, R. Shapiro, R. Zash, M. F. Silveira, R. Buffarini, P. Kolsteren, C. Lachat, L. Huybregts, D. Roberfroid, L. Zeng, Z. Zhu, J. He, X. Qiu, S. H. Gebreyesus, K. Tesfamariam, D. Bekele, G. Chan, E. Baye, F. Workneh, K. P. Asante, E. B. Kaali, S. Adu‐Afarwuah, K. G. Dewey, S. Gyaase, B. J. Wylie, B. R. Kirkwood, A. Manu, R. D. Thulasiraj, J. Tielsch, R. Chowdhury, S. Taneja, G. R. Babu, P. Shriyan, P. Ashorn, K. Maleta, U. Ashorn, C. Mangani, S. Acevedo‐Gallegos, M. J. Rodriguez‐Sibaja, S. K. Khatry, S. C. LeClerq, L. C. Mullany, F. Jehan, M. Ilyas, S. J. Rogerson, H. W. Unger, R. Ghosh, S. Musange, V. Ramokolo, W. Zembe‐Mkabile, M. Lazzerini, M. Rishard, D. Wang, W. W. Fawzi, D. T. R. Minja, C. Schmiegelow, H. Masanja, E. Smith, J. P. A. Lusingu, O. A. Msemo, F. M. Kabole, S. N. Slim, P. Keentupthai, A. Mongkolchati, R. Kajubi, A. Kakuru, P. Waiswa, D. Walker, D. H. Hamer, K. E. A. Semrau, E. B. Chaponda, R. M. Chico, B. Banda, K. Musokotwane, A. Manasyan, J. M. Pry, B. Chasekwa, J. Humphrey, R. E. Black, the Subnational Vulnerable Newborn Prevalence Collaborative Group and Vulnerable Newborn Measurement Core Group, Hasmot Ali, Parul Christian, Rolf D. W. Klemm, Alan B. Massie, Maithili Mitra, Sucheta Mehra, Kerry J. Schulze, Abu Ahmed Shamim, Alfred Sommer, MD. Barkat Ullah, Keith P. West, Nazma Begum, Nabidul Haque Chowdhury, Md. Shafiqul Islam, Dipak Kumar Mitra, Abdul Quaiyum, Modiegi Diseko, Joseph Makhema, Yue Cheng, Yixin Guo, Shanshan Yuan, Meselech Roro, Bilal Shikur, Frederick Goddard, Sebastien Haneuse, Bezawit Hunegnaw, Yemane Berhane, Alemayehu Worku, Seyram Kaali, Charles D. Arnold, Darby Jack, Seeba Amenga‐Etego, Lisa Hurt, Caitlin Shannon, Seyi Soremekun, Nita Bhandari, Jose Martines, Sarmila Mazumder, Yamuna Ana, R Deepa, Lotta Hallamaa, Juha Pyykkö, Mario I. Lumbreras‐Marquez, Claudia E. Mendoza‐Carrera, Atiya Hussain, Muhammad Karim, Farzana Kausar, Usma Mehmood, Naila Nadeem, Muhammad Imran Nisar, Muhammad Sajid, Ivo Mueller, Maria Ome‐Kaius, Elizabeth Butrick, Felix Sayinzoga, Ilaria Mariani, Willy Urassa, Thor Theander, Phillippe Deloron, Birgitte Bruun Nielsen, Alfa Muhihi, Ramadhani Abdallah Noor, Ib Bygbjerg, Sofie Lykke Moeller, Fahad Aftab, Said M. Ali, Pratibha Dhingra, Usha Dhingra, Arup Dutta, Sunil Sazawal, Atifa Suleiman, Mohammed Mohammed, Saikat Deb, Moses R. Kamya, Miriam Nakalembe, Jude Mulowooz, Nicole Santos, Godfrey Biemba, Julie M. Herlihy, Reuben K. Mbewe, Fern Mweena, Kojo Yeboah‐Antwi, Jane Bruce, Daniel Chandramohan, Andrew Prendergast, Joy E. Lawn, Hannah Blencowe, Eric Ohuma, Yemi Okwaraji, Judith Yargawa, Ellen Bradley, Joanne Katz   +189 more
wiley   +1 more source

Randomized Comparison of Amodiaquine plus Sulfadoxine-Pyrimethamine, Artemether-Lumefantrine, and Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in Burkina Faso [PDF]

Clinical Infectious Diseases, 2007
Philip J Rosenthal
exaly   +2 more sources

Chloroquine and Sulfadoxine Derivatives Inhibit ZIKV Replication in Cervical Cells

Viruses, 2020
Despite the severe morbidity caused by Zika fever, its specific treatment is still a challenge for public health. Several research groups have investigated the drug repurposing of chloroquine.
Audrien Alves Andrade de Souza, Lauana Ribas Torres, Lyana Rodrigues Pinto Lima Capobianco, Vanessa Salete de Paula, Cynthia Machado Cascabulho, Kelly Salomão, Maria da Gloria Bonecini-Almeida, Maria de Lourdes Garcia Ferreira, Nubia Boechat, Luiz Carlos da Silva Pinheiro, Elen Mello de Souza   +10 more
doaj   +1 more source

Decreasing burden of malaria in pregnancy in Malawian women and its relationship to use of intermittent preventive therapy or bed nets. [PDF]

PLoS ONE, 2010
The World Health Organization recommends insecticidal bednets and intermittent preventive treatment to reduce malaria in pregnancy. Longitudinal data of malaria prevalence and pregnancy outcomes are valuable in gauging the impact of these antimalarial ...
Gaoqian Feng, Julie A Simpson, Ebbie Chaluluka, Malcolm E Molyneux, Stephen J Rogerson   +4 more
doaj   +1 more source