Results 31 to 40 of about 10,379 (219)
A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum
Angewandte Chemie International Edition, Volume 64, Issue 49, December 1, 2025.Compound 31 represents a promising avenue for the development as an antimalarial agent with a potent activity profile (PfNF54 IC50 ± s.d. = 3.9 ± 0.4 nM). It has a novel mode of action by binding to cytosolic ribosomal subunits, thereby inhibiting protein synthesis in the parasite.
Patricia Bravo +16 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, Volume 171, Issue 3, Page 993-1007, December 2025.Abstract Anemia affects 32 million pregnant women globally, contributing annually to more than 115 000 maternal deaths and 591 000 perinatal deaths worldwide. Low‐ and middle‐income countries (LMICs) bear the highest burden of anemia in pregnancy, with nearly 50% of affected pregnant women. It is now 2025, which is WHO's target year for a 50% reduction
Akaninyene E. Ubom +9 more
wiley +1 more source
PLoS ONE, 2019 AimIntermittent preventive treatment in pregnancy (IPTp) with azithromycin and monthly sulfadoxine-pyrimethamine increased the mean child weight, mid-upper arm and head circumference at four weeks of age in a rural low-income setting.
Lotta Hallamaa +6 more
doaj +1 more source
Pregnancy Intentions and Maternal Health Behaviours: Observational Study in 18 African Countries
BJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue 13, Page 2246-2255, December 2025.ABSTRACT Objective This study explores the relationship between pregnancy intentions and maternal health behaviours. Design and Setting Secondary data analysis of recent (2018–2023), cross‐sectional demographic and health surveys from 18 sub‐Saharan African countries.
Bolanle Olapeju +9 more
wiley +1 more source
Frequency of Pfcrt T76 and Pfdhfr Asn-108 Drug Resistance Mutations in falciparum Malaria in Southeastern Malaria Endemic Area of Iran [PDF]
Iranian Journal of Public Health, 2008 Background: Point mutations in the genes, Pfcrt and Pfdhfr, have been identified elsewhere as strongly associated with resistance to chloroquine (CQ) and pyrimethamine, respectively.
MR Razavi +5 more
doaj +1 more source
Journal of Analytical Methods in Chemistry, 2022 Falsified drugs are of serious concern to public health worldwide, particularly for developing countries where quality control of drugs is inefficient.
Moussa Yabré +6 more
doaj +1 more source
Clinical Case Reports, Volume 13, Issue 11, November 2025.ABSTRACT Guillain–Barré syndrome (GBS) is an acute immune‐mediated polyradiculoneuropathy often triggered by infections. Malaria, a common parasitic disease in endemic regions, has rarely been associated with GBS. We report a case of a 21‐year‐old male from rural Ethiopia who developed GBS following Plasmodium vivax malaria.
Hayatu Awel Abdela +2 more
wiley +1 more source
Artesunate-, sulfadoxine-, and pyrimethamine-induced cardiotoxicity
BLDE University Journal of Health Sciences, 2016 Here, we report oral artesunate, sulphadoxine and pyrimethamine (sp) induced cardio toxicity case in a female patient. Artesunate is a highly efficacious and relatively safe antimalarial drug.
Divya Goel +3 more
doaj +1 more source
Malaria Journal, 2023 Background Exposure during pregnancy to malaria and sexually-transmitted infections is associated with adverse birth outcomes including low birth weight (LBW).
Moussa Lingani +14 more
doaj +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, Volume 132, Issue S8, Page S20-S36, November 2025.Abstract Objective To examine prevalence of novel newborn types among 541 285 live births in 23 countries from 2000 to 2021. Design Descriptive multi‐country secondary data analysis. Setting Subnational, population‐based birth cohort studies (n = 45) in 23 low‐ and middle‐income countries (LMICs) spanning 2000–2021.
D. J. Erchick +189 more
wiley +1 more source