Results 41 to 50 of about 10,197 (217)
A Novel Antimalarial Agent that Inhibits Protein Synthesis in Plasmodium falciparum
Angewandte Chemie International Edition, EarlyView.Compound 31 represents a promising avenue for the development as an antimalarial agent with a potent activity profile (PfNF54 IC50 ± s.d. = 3.9 ± 0.4 nM). It has a novel mode of action by binding to cytosolic ribosomal subunits, thereby inhibiting protein synthesis in the parasite.
Patricia Bravo +16 more
wiley +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Anemia affects 32 million pregnant women globally, contributing annually to more than 115 000 maternal deaths and 591 000 perinatal deaths worldwide. Low‐ and middle‐income countries (LMICs) bear the highest burden of anemia in pregnancy, with nearly 50% of affected pregnant women. It is now 2025, which is WHO's target year for a 50% reduction
Akaninyene E. Ubom +9 more
wiley +1 more source
Pregnancy Intentions and Maternal Health Behaviours: Observational Study in 18 African Countries
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective This study explores the relationship between pregnancy intentions and maternal health behaviours. Design and Setting Secondary data analysis of recent (2018–2023), cross‐sectional demographic and health surveys from 18 sub‐Saharan African countries.
Bolanle Olapeju +9 more
wiley +1 more source
PLoS ONE, 2019 AimIntermittent preventive treatment in pregnancy (IPTp) with azithromycin and monthly sulfadoxine-pyrimethamine increased the mean child weight, mid-upper arm and head circumference at four weeks of age in a rural low-income setting.
Lotta Hallamaa +6 more
doaj +1 more source
Journal of Analytical Methods in Chemistry, 2022 Falsified drugs are of serious concern to public health worldwide, particularly for developing countries where quality control of drugs is inefficient.
Moussa Yabré +6 more
doaj +1 more source
Frequency of Pfcrt T76 and Pfdhfr Asn-108 Drug Resistance Mutations in falciparum Malaria in Southeastern Malaria Endemic Area of Iran [PDF]
Iranian Journal of Public Health, 2008 Background: Point mutations in the genes, Pfcrt and Pfdhfr, have been identified elsewhere as strongly associated with resistance to chloroquine (CQ) and pyrimethamine, respectively.
MR Razavi +5 more
doaj +1 more source
Malaria Journal, 2023 Background Exposure during pregnancy to malaria and sexually-transmitted infections is associated with adverse birth outcomes including low birth weight (LBW).
Moussa Lingani +14 more
doaj +1 more source
Maternal &Child Nutrition, Volume 21, Issue 4, October 2025.Globally nearly 40% of children under 5 years old are anaemic, which affects their ability to grow and develop. A cluster randomised trial was conducted in 60 communities in Southern Mali to evaluate the added impact of home fortification with micronutrient powders, delivered alongside seasonal malaria chemoprevention, on anaemia, malaria infection ...
Niélé H. Diarra +18 more
wiley +1 more source
BMC Infectious Diseases, 2022 Background Uganda accounts for 5% of all malaria cases and deaths reported globally and, in endemic countries, pregnancy is a risk factor for both acquisition of P. falciparum infection and development of severe malaria.
Francesco Vladimiro Segala +19 more
doaj +1 more source
Journal of Evidence-Based Medicine, Volume 18, Issue 3, September 2025.ABSTRACT Objective To evaluate zinc supplementation's efficacy in pregnancy, addressing gaps in previous reviews regarding high‐risk subgroups and combination therapies. Methods Systematic review of six databases through March 27, 2025 for randomized controlled trials (RCTs) on prenatal zinc supplementation. Risk of bias was assessed using the Cochrane
Sha Diao +6 more
wiley +1 more source