Results 131 to 140 of about 3,260 (184)

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang   +14 more
wiley   +1 more source

Trajectories of Treatment Disruption for Chronic Outpatient Medications for U.S. Veterans During Drug Shortages

open access: yesPharmacoepidemiology and Drug Safety, Volume 35, Issue 6, June 2026.
ABSTRACT Introduction Although drug shortages for outpatient chronic conditions commonly occur, population‐level data on how they impact patients' ability to refill prescriptions is scarce. We sought to identify distinct patterns of refill adherence following drug shortages and patient‐ and prescription‐level factors associated with adherence ...
Katie J. Suda   +14 more
wiley   +1 more source

A case report of alopecia totalis associated with permanent hair dye use

open access: yesJAAD Case Reports, 2020
Leila K. Asadi   +2 more
doaj   +1 more source

Understanding Patient and Gastroenterologist Preferences at the Time of Treatment Escalation to First‐Line Advanced Therapy in Ulcerative Colitis: A Discrete Choice Experiment in Five European Countries

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 5, June 2026.
ABSTRACT Background With guidelines recommending earlier advanced therapy (AT) use after 5‐ASA failure for patients with moderately‐to‐severely active ulcerative colitis (UC), it is important to explore treatment preferences at the point of escalation to first‐line AT.
Stefan Schreiber   +12 more
wiley   +1 more source

Epicutaneous and Drug Provocation Testing in Severe Cutaneous Adverse Reactions: A 20‐Year Single‐Centre Experience

open access: yesContact Dermatitis, Volume 94, Issue 6, Page 677-688, June 2026.
This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli   +8 more
wiley   +1 more source

Flare risk after oral glucocorticoid bridging with methotrexate or intra‐articular bridging with triple therapy in early rheumatoid arthritis

open access: yesJournal of Internal Medicine, Volume 299, Issue 6, Page 741-753, June 2026.
Abstract Objectives To investigate, in early rheumatoid arthritis, whether bridging with glucocorticoids (GCs) is associated with an increased risk of flare following GC tapering and withdrawal. Methods A total of 810 NOrdic Rheumatic Diseases Strategy Trials And Registries (NORD‐STAR) patients were included in this post hoc analysis: all received ...
Kristina Lend   +16 more
wiley   +1 more source

Sulfasalazine-Induced Major Depressive Disorder With Psychotic Features

open access: yes, 2018
Ankilozan spondilit (AS); nedeni bilinmeyen, esasen omurgayı olmak üzere diğer eklemleri de etkileyebilen kronik inflamatuar bir hastalıktır. AS, spondiloartropatilerin prototipi olup dünya nüfusunun % 0,9'unu etkilemektedir.
Tomarbozkurt, Hazan M.D.   +3 more
core  

The antiinflammatory moiety of sulfasalazine, 5-aminosalicylic acid, is a radical scavenger

open access: yes, 1987
Using a novel spectrophotometric assay to detect free radical scavengers, the effects of sulfasalazine, a compound frequently administered in the treatment of chronic inflammatory bowel disease, and its main metabolites, 5-aminosalicylic acid (5-ASA ...
Nielsen, O H, Ahnfelt-Rønne, I
core  

PROTECTIVE EFFECTS OF QUERCETIN AND RUTIN ON SULFASALAZINE-INDUCED TESTICULAR TOXICITY AND APOPTOSIS IN MALE WISTAR RATS

open access: yes, 2015
A Thesis in the Department of Biochemistry submitted to the Faculty of Basic Medical Sciences in partial fulfillment of the requirements for the award of the degree of Doctor of Philosophy, University of Ibadan, Nigeria.Sulfasalazine is used as a therapy
OSAWE, S. O.
core  
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Sulfasalazine

Drugs, 2012
Greg L Plosker   +2 more
exaly   +4 more sources

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