Results 111 to 120 of about 12,850 (181)
Aim and Background: Anti-inflammatory compounds are effective in improving the symptoms of inflammatory bowel diseases such as ulcerative colitis. The aim of this study was to evaluate the effect of aloe vera extract against the inflammatory factors ...
zakieh keshavarzi +3 more
doaj
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source
Sulfasalazine plus Chloroquine-Induced Mood Disorder in a Patient with Rheumatoid Arthritis [PDF]
Rheumatoid arthritis is a chronic systemic inflammatory diseasethat affects approximately 0.5-1% of the world population.The current approach to this disease is to start an intensivetreatment without delay once the disease has developed.Various studies ...
Gulcan Gulec +2 more
doaj
Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang +14 more
wiley +1 more source
Risk-stratified monitoring for sulfasalazine toxicity: prognostic model development and validation
Background Sulfasalazine-induced cytopenia, nephrotoxicity and hepatotoxicity is uncommon during long-term treatment. Some guidelines recommend 3 monthly monitoring blood tests indefinitely during long-term treatment while others recommend stopping ...
Abhishek Abhishek +10 more
doaj +1 more source
Drug‐induced hypersensitivity syndrome followed by exacerbation of Crohn's disease
Pediatric Investigation, EarlyView.
Mei Kamidani +10 more
wiley +1 more source
This study provides reassuring evidence in favour of early skin testing in patients with SCARs, argues against the necessity of a 6‐month delay, and underscores the pivotal role of oral provocation tests in the safe reintroduction of essential therapies. ABSTRACT Background Identifying and discontinuing the offending drug(s) in severe cutaneous adverse
Zohra Chadli +8 more
wiley +1 more source
Abstract Objectives To investigate, in early rheumatoid arthritis, whether bridging with glucocorticoids (GCs) is associated with an increased risk of flare following GC tapering and withdrawal. Methods A total of 810 NOrdic Rheumatic Diseases Strategy Trials And Registries (NORD‐STAR) patients were included in this post hoc analysis: all received ...
Kristina Lend +16 more
wiley +1 more source
Phaeochromocytomas and paragangliomas (PPGLs) are catecholamine-secreting neuroendocrine tumours (NETs) of the adrenal medulla and autonomic nervous system. Early recognition and management is critical given their potential morbidity and mortality.
Maria Hadjicosti +5 more
doaj +1 more source

