Results 111 to 120 of about 26,729 (245)

A Prospective Randomized Controlled Trial to Study the Role of Sulfasalazine in the Prevention of Acute Gastrointestinal Toxicities in Patients of Carcinoma of the Cervix Receiving Concurrent Chemoradiation

South Asian Journal of Cancer
The present study aimed to evaluate the effectiveness of sulfasalazine in preventing acute gastrointestinal (GI) toxicities in patients with cervical carcinoma receiving concurrent chemoradiation.
Vasireddy Abhinav, Naga Chandra Sekhar Darisi, Amrutha Iyyapu, V.L Anusha Konakalla   +3 more
doaj   +1 more source

Expression of fibronectin and MMP-3 and its significance in the patients with ankylosing spondylitis

Asian Pacific Journal of Tropical Medicine, 2018
Objective: To observe the expression and significance of fibronectin and metalloproteinase-3 (MMP-3) in patients with ankylosing spondylitis (AS). Methods: A total of 30 AS patients in our hospital and 30 healthy volunteers were selected in our study ...
Jun-Ling Zhu, Jian-Yao Zhou, Tao Hou, Jian-Zhi Zhao, Guo-Fang Wang, Xiao-Wei Han   +5 more
doaj   +1 more source

Targeting the NR3C1‐ACSL4 Axis Triggers Ferroptosis to Overcome Radioresistance in Prostate Cancer

Cancer Science, EarlyView.
The glucocorticoid receptor NR3C1 drives prostate cancer radioresistance by upregulating ACSL4. High ACSL4 levels create a lipid metabolic vulnerability. The clinical agent DHA synergizes with ACSL4 to induce lipid peroxidation and ferroptosis, effectively overcoming radioresistance.
Jing Yang, Puyuan Chen, Yawen Zheng, Feiyue Shi, Min Wang, Luwei Xu, Xiaowei Wei, Xiumei Wang   +7 more
wiley   +1 more source

Case report: lichen planus in a patient with ulcerative colitis receiving sulfasalazine: a drug effect or a disease manifestation?

Future Science OA
Lichen Planus is an inflammatory skin disease that has been reported to be associated with inflammatory diseases like Inflammatory Bowel Disease or with medication use such as sulfasalazine. We report a case of lichen planus in a 62-year-old patient with
Ahmed Mohamed Nefzi, Haythem Yacoub, Asmahane Souissi, Hajer Hassine, Dhouha Cherif, Habiba Debbabi, Héla Kchir, Nadia Maamouri   +7 more
doaj   +1 more source

Protective Effect of Aloe Vera Gel in Ulcerative Colitis: The Role of Inflammatory and Anti-Inflammatory Factors

مجله علمی دانشگاه علوم پزشکی کردستان, 2021
Aim and Background: Anti-inflammatory compounds are effective in improving the symptoms of inflammatory bowel diseases such as ulcerative colitis. The aim of this study was to evaluate the effect of aloe vera extract against the inflammatory factors ...
zakieh keshavarzi, Mosa-Al- Reza Hadjzadeh, masoud nazari, roghaye Arezumand   +3 more
doaj  

Fibrillar‐Type Dermatitis Herpetiformis: An Underrecognized Variant That Is Rarely Associated With Celiac Disease and Lacking Epidermal Transglutaminase Deposition: A Report of Two Cases

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Dermatitis herpetiformis (DH) is a rare, intensely pruritic cutaneous manifestation of celiac disease (CD), typically presenting with excoriated papulovesicular lesions on extensor surfaces. DH is associated with IgA autoantibodies against epidermal transglutaminase (eTG), which form granular immune deposits in the papillary dermis and induce ...
Jeffrey Damman, Elodie Mendels, Sven van der Woude, Sharon Veenbergen, Gilles F. H. Diercks, Martijn B. van Doorn   +5 more
wiley   +1 more source

Sulfasalazine plus Chloroquine-Induced Mood Disorder in a Patient with Rheumatoid Arthritis [PDF]

Iranian Journal of Medical Sciences, 2009
Rheumatoid arthritis is a chronic systemic inflammatory diseasethat affects approximately 0.5-1% of the world population.The current approach to this disease is to start an intensivetreatment without delay once the disease has developed.Various studies ...
Gulcan Gulec, Cinar Yenilmez, Unal Ayranci   +2 more
doaj  

Direct transition to a streamlined rheumatoid arthritis clinic improves outcomes after discharge from an early arthritis clinic environment

Internal Medicine Journal, EarlyView.
Abstract Background The treat‐to‐target (T2T) strategy for the management of rheumatoid arthritis (RA) achieves remission or low disease activity in many patients. However, RA T2T is challenging in real‐world clinical environments. In this two‐stage audit, we evaluated the impact of transferring patients from a T2T intensive early arthritis clinic (EAC)
Hyunjun Jonathan Kim, Mitsi Blazos, Kevin Yen Chia Su, Ranjeny Thomas, Helen Benham   +4 more
wiley   +1 more source

Sulfasalazine-induced renal injury in rats and the protective role of thiol-reductants [PDF]

, 2015
Sulfasalazine is widely used for inflammatory-mediated disorders in human. Renal damage is a serious adverse effect accompanied sulfasalazine administration. No specific therapeutic option is available against this complication so far.
Heidari, R, Rahimi, HR, Shirazi Yeganeh, B, Najibi, A, Taheri, V, Niknahad, H   +5 more
core  

Sulfasalazine in Prevention of Pouchitis After Proctocolectomy with Ileal Pouch–Anal Anastomosis for Ulcerative Colitis

, 2017
Background: Pouchitis is the most frequent complication after ileal pouch–anal anastomosis for refractory ulcerative colitis. A non-standardized preventative treatment exists. Sulfasalazine has proved effective in acute pouchitis therapy.
SCAIOLI, ELEONORA, SARTINI, ALESSANDRO, BELLUZZI, ANDREA, ROSATI, GIANCARLO, FESTI, DAVIDE, Digby, Richard John, POGGIOLI, GILBERTO, LIVERANI, ELISA, BAZZOLI, FRANCO, UGOLINI, GIAMPAOLO   +9 more
core   +1 more source