Results 61 to 70 of about 31,866 (306)

Cloning and Characterization of a Novel N-Acetyl-D-galactosamine-4-O-sulfate Sulfatase, SulA1, from a Marine Arthrobacter Strain

open access: yesMarine Drugs
Sulfation is gaining increased interest due to the role of sulfate in the bioactivity of many polysaccharides of marine origin. Hence, sulfatases, enzymes that control the degree of sulfation, are being more extensively researched.
Monica Daugbjerg Christensen   +8 more
doaj   +1 more source

Enzyme replacement therapies: What is the best option? [PDF]

open access: yes, 2018
Despite many beneficial outcomes of the conventional enzyme replacement therapy (ERT), several limitations such as the high-cost of the treatment and various inadvertent side effects including the occurrence of an immunological response against the ...
Barar, Jaleh   +4 more
core   +2 more sources

A Simple Method for On-Gel Detection of Myrosinase Activity

open access: yesMolecules, 2018
Myrosinase is an enzyme present in many functional foods and spices, particularly in Cruciferous vegetables. It hydrolyses glucosinolates which thereafter rearrange into bioactive volatile constituents (isothiocyanates, nitriles).
Sándor Gonda   +6 more
doaj   +1 more source

Mycobacterium tuberculosis Rv3406 is a type II alkyl sulfatase capable of sulfate scavenging. [PDF]

open access: yesPLoS ONE, 2013
The genome of Mycobacterium tuberculosis (Mtb) encodes nine putative sulfatases, none of which have a known function or substrate. Here, we characterize Mtb's single putative type II sulfatase, Rv3406, as a non-heme iron (II) and α-ketoglutarate ...
Kimberly M Sogi   +5 more
doaj   +1 more source

Toxicology Study of Intra-Cisterna Magna Adeno-Associated Virus 9 Expressing Iduronate-2-Sulfatase in Rhesus Macaques

open access: yesMolecular Therapy: Methods & Clinical Development, 2018
Hunter syndrome is an X-linked recessive disease caused by deficiency of the lysosomal enzyme iduronate-2-sulfatase. The severe form of this progressive, systemic, and neurodegenerative disease results in loss of cognitive skills and early death. Several
J. Hordeaux   +7 more
semanticscholar   +1 more source

Comparative Study of Two Chondroitin Sulfate/Dermatan Sulfate 4-O-Sulfatases With High Identity

open access: yesFrontiers in Microbiology, 2019
Chondroitin sulfate/dermatan sulfate (CS/DS) sulfatases are potential tools for structural and functional studies of CD/DS chains. In our previous study, a CS/DS 4-O-endosulfatase (endoVB4SF) was identified from a marine bacterium (Wang et al., 2015 ...
Shumin Wang   +6 more
doaj   +1 more source

Quantification of Dehydroepiandrosterone, 17β-Estradiol, Testosterone, and Their Sulfates in Mouse Tissues by LC-MS/MS. [PDF]

open access: yes, 2019
We report a high-performance, liquid chromatography/tandem mass spectrometry (HPLC-MS/MS) assay to quantify without derivatizaton dehyroepiandrosterone (DHEA), 17β-estradiol (E2), testosterone (T), and their sulfates in serum and tissues.
Napoli, Joseph L, Yoo, Hong Sik
core  

The effect of organic management on soil quality indicators [PDF]

open access: yes, 2002
This report was presented at the UK Organic Research 2002 Conference. A range of physical, biological and chemical parameters were measured in organic soil that had been managed in different ways and in a conventional control.
Bending, Gary D   +5 more
core  

SPASM and Twitch Domains in S-Adenosylmethionine (SAM) Radical Enzymes [PDF]

open access: yes, 2014
S-Adenosylmethionine (SAM, also known as AdoMet) radical enzymes use SAM and a [4Fe-4S] cluster to catalyze a diverse array of reactions. They adopt a partial triose-phosphate isomerase (TIM) barrel fold with N- and C-terminal extensions that tailor the ...
Drennan, Catherine L.   +2 more
core   +1 more source

CO2 Fluxes and Soil Responses to Straw and Herbicide in Peanut

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Peanut cultivation plays an important agronomic role in Brazil, especially in rotation with sugarcane, promoting biological nitrogen fixation and improving soil quality. This study aimed to test the hypothesis that the combined use of sugarcane mulch, peanut cultivation, and herbicide application would affect soil CO₂ fluxes, soil chemical ...
Heytor Lemos Martins   +7 more
wiley   +1 more source

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