Results 61 to 70 of about 28,914 (292)

Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer

open access: yesMolecular Cancer, 2005
Hsulf-1 is a newly identified enzyme, which has the ability to decrease the growth of hepatocellular, ovarian, and head and neck squamous cell carcinoma cells by interfering with heparin-binding growth factor signaling.
Giese Nathalia A   +8 more
doaj   +1 more source

Structure of a human lysosomal sulfatase [PDF]

open access: yesStructure, 1997
. Sulfatases catalyze the hydrolysis of sulfuric acid esters from a wide variety of substrates including glycosaminoglycans, glycolipids and steroids. There is sufficient common sequence similarity within the class of sulfatase enzymes to indicate that they have a common structure.
Bond, C.   +6 more
openaire   +4 more sources

Symbiotic Human Gut Bacteria with Variable Metabolic Priorities for Host Mucosal Glycans. [PDF]

open access: yes, 2015
UnlabelledMany symbiotic gut bacteria possess the ability to degrade multiple polysaccharides, thereby providing nutritional advantages to their hosts.
German, J Bruce   +5 more
core   +2 more sources

Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity

open access: yesFrontiers in Oncology, 2019
Membrane heparan sulfate proteoglycans (HSPG) regulate cell proliferation, migration, and differentiation and are therefore considered key players in cancer cell development processes.
Jlenia Brunetti   +9 more
doaj   +1 more source

Alkyl Sulfatase of Cholera Vibrios

open access: yesПроблемы особо опасных инфекций, 2023
The aim of the work was to study the structure of the alkyl sulfatase (asu) gene in Vibrio cholerae strains of various serogroups, as well as to compare nucleotide and amino acid sequences of alkyl sulfatases using various methods of bioinformatic ...
O. V. Duvanova   +8 more
doaj   +1 more source

International guidelines for the management and treatment of Morquio A syndrome. [PDF]

open access: yes, 2014
Morquio A syndrome (mucopolysaccharidosis IVA) is a lysosomal storage disorder associated with skeletal and joint abnormalities and significant non-skeletal manifestations including respiratory disease, spinal cord compression, cardiac disease, impaired ...
Berger, Kenneth I   +8 more
core   +2 more sources

Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou   +4 more
wiley   +1 more source

High-Throughput, Lysis-free Screening for Sulfatase Activity Using Escherichia coli Autodisplay in Microdroplets

open access: yesbioRxiv, 2018
Directed evolution of enzymes toward improved catalytic performance has become a powerful tool in protein engineering. To be effective, a directed evolution campaign requires the use of high-throughput screening. In this study we describe the development
B. Loo   +9 more
semanticscholar   +1 more source

Sulfatase Assay to Determine Influence of Plants on Microbial Activity in Soil

open access: yesBio-Protocol, 2020
Sulfatase activity is often used as a measure of the activity of soil microorganisms. It is thus a suitable tool to investigate the response of microbes to plants.
Anna Koprivova   +2 more
doaj   +1 more source

Colorimetric Determination of Sulfate via an Enzyme Cascade for High-Throughput Detection of Sulfatase Activity.

open access: yesAnalytical Chemistry, 2018
High-throughput screening (HTS) methods have become decisive for the discovery and development of new biocatalysts and their application in numerous fields.
Jose G. Ortiz-Tena   +2 more
semanticscholar   +1 more source

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