Results 121 to 130 of about 3,093 (180)

Biochemical signatures of disease severity in multiple sulfatase deficiency. [PDF]

open access: yesJ Inherit Metab Dis
Adang LA   +15 more
europepmc   +1 more source

The Discovery of Endo-Fucanases in the GH141 Family: A Novel Functional Activity Within the Family. [PDF]

open access: yesInt J Mol Sci
Rubtsov NK   +6 more
europepmc   +1 more source

Sulfated mannan helps diatoms domesticate their microbiome

open access: yes
Krull J   +12 more
europepmc   +1 more source
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SULFATASES AND HUMAN DISEASE

Annual Review of Genomics and Human Genetics, 2005
▪ Abstract  Sulfatases are a highly conserved family of proteins that cleave sulfate esters from a wide range of substrates. The importance of sulfatases in human metabolism is underscored by the presence of at least eight human monogenic diseases caused by the deficiency of individual sulfatases. Sulfatase activity requires a unique posttranslational
Andrea Ballabio
exaly   +4 more sources

Steroid sulfatase inhibitors

Expert Opinion on Therapeutic Patents, 2003
AbstractSteroid sulfatase (STS) regulates the local production of estrogens and androgens from systemic precursors in several tissues. The enzyme catalyzes the hydrolysis of the sulfate esters of 3‐hydroxy steroids, which are inactive transport or precursor forms of the active 3‐hydroxy steroids.
Peter, Nussbaumer, Andreas, Billich
openaire   +2 more sources

Multiple sulfatase deficiency

Neurology, 1988
Multiple sulfatase deficiency is an inherited disorder characterized by a deficiency of several sulfatases and the accumulation of sulfatides, glycosaminoglycans, sphingolipids, and steroid sulfates in tissues and body fluids. The clinical manifestations represent the summation of two diseases: late infantile metachromatic leukodystrophy and ...
B W, Soong   +4 more
openaire   +2 more sources

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