Results 21 to 30 of about 14,179 (284)

New Insights into the Plutella xylostella Detoxifying Enzymes: Sequence Evolution, Structural Similarity, Functional Diversity, and Application Prospects of Glucosinolate Sulfatases [PDF]

Journal of Agricultural and Food Chemistry, 2023
Brassica plants have glucosinolate (GLs)-myrosinase defense mechanisms to deter herbivores. However, Plutella xylostella specifically feeds on Brassica vegetables.
Wei Chen, Muhammad Bilal Amir, Yuan Liao, Hai‐Zhong Yu, Weiyi He, Zhanjun Lu   +5 more
openalex   +2 more sources

Secreted sulfatases Sulf1 and Sulf2 have overlapping yet essential roles in mouse neonatal survival.

PLoS ONE, 2007
BackgroundHeparan sulfate proteoglycans (HSPGs) use highly sulfated polysaccharide side-chains to interact with several key growth factors and morphogens, thereby regulating their accessibility and biological activity.
Charles R Holst, Hani Bou-Reslan, Bryan B Gore, Karen Wong, Deanna Grant, Sreedevi Chalasani, Richard A Carano, Gretchen D Frantz, Marc Tessier-Lavigne, Brad Bolon, Dorothy M French, Avi Ashkenazi   +11 more
doaj   +2 more sources

Functions and specificity of bacterial carbohydrate sulfatases targeting host glycans. [PDF]

Essays Biochem, 2023
Sulfated host glycans (mucin O-glycans and glycosaminoglycans [GAGs]) are critical nutrient sources and colonisation factors for Bacteroidetes of the human gut microbiota (HGM); a complex ecosystem comprising essential microorganisms that coevolved with ...
Luis AS, Yates EA, Cartmell A.
europepmc   +2 more sources

Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota

Nature Chemical Biology, 2022
Sulfated glycans are ubiquitous nutrient sources for microbial communities that have coevolved with eukaryotic hosts. Bacteria metabolize sulfated glycans by deploying carbohydrate sulfatases that remove sulfate esters.
A. Luis, A. Baslé, D. Byrne, G. Wright, James A. London, C. Jin, N. Karlsson, G. Hansson, P. Eyers, M. Czjzek, T. Barbeyron, E. Yates, E. Martens, A. Cartmell   +13 more
semanticscholar   +1 more source

The Role of Sulfation in Nematode Development and Phenotypic Plasticity

Frontiers in Molecular Biosciences, 2022
Sulfation is poorly understood in most invertebrates and a potential role of sulfation in the regulation of developmental and physiological processes of these organisms remains unclear. Also, animal model system approaches did not identify many sulfation-
Catia Igreja, Ralf J. Sommer
doaj   +1 more source

Mammalian Sulfatases: Biochemistry, Disease Manifestation, and Therapy

International Journal of Molecular Sciences, 2022
Sulfatases are enzymes that catalyze the removal of sulfate from biological substances, an essential process for the homeostasis of the body. They are commonly activated by the unusual amino acid formylglycine, which is formed from cysteine at the ...
R. Mashima, M. Nakanishi
semanticscholar   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

Hiding in plain sight: the globally distributed bacterial candidate phylum PAUC34f [PDF]

, 2020
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Chen, M. L., Becraft, E. D., Pachiadaki, M., Brown, J. M., Jarett, J. K., Gasol, J. M., Ravin, N.
Becraft, Eric D., Brown, Julia M., Chen, Michael L., Gasol, Josep M., Herndl, Gerhard J., Jarett, Jessica K., Moser, Duane P., Nunoura, Takuro, Pachiadaki, Maria G., Ravin, Nikolai V., Stepanauskas, Ramunas, Woyke, Tanja   +11 more
core   +2 more sources

Steroid Sulfatase Deficiency [PDF]

Pediatric Research, 1977
Placental steroid sulfatase deficiency is a genetic disorder only recently reported in the medical literature. Most documented cases of placental sulfatase deficiency have been marked by delay in onset of labor, lack of cervical dilatation, and relative refractoriness of oxytocic agents and amniotomy. We have studied the placenta, cultured fibroblasts,
L J, Shapiro, L, Cousins, A L, Fluharty, R L, Stevens, H, Kihara   +4 more
openaire   +2 more sources

Mycobacterium tuberculosis Rv3406 is a type II alkyl sulfatase capable of sulfate scavenging. [PDF]

PLoS ONE, 2013
The genome of Mycobacterium tuberculosis (Mtb) encodes nine putative sulfatases, none of which have a known function or substrate. Here, we characterize Mtb's single putative type II sulfatase, Rv3406, as a non-heme iron (II) and α-ketoglutarate ...
Kimberly M Sogi, Zev J Gartner, Mark A Breidenbach, Mason J Appel, Michael W Schelle, Carolyn R Bertozzi   +5 more
doaj   +1 more source