Results 131 to 140 of about 700,714 (339)

Preparation and purification of Flavobacterium heparinum chondroitinases AC and B by hydrophobic interaction chromatography [PDF]

, 1999
Flavobacterium heparinum is a soil bacterium that produces several mucopolysaccharidases such as heparinase, heparitinases I and II, and chondroitinases AC, B, C and ABC. The purpose of the present study was to optimize the preparation of F.
Aguiar, Jair Adriano Kopke, Michelacci, Yara Maria   +1 more
core   +1 more source

Structure and Bioactivity of Sulfated Polysaccharides

Trends in Glycoscience and Glycotechnology, 2003
グリコサミノグリカンを含む酸性多糖類は様々な化学的、生物学的な機能を示す。これらの機能の多くは硫酸基の存在に強く依存している。よってこれら多糖類の部分的硫酸化、完全硫酸化あるいは脱硫酸化などの化学的修飾は、硫酸化多糖の示す機能を制御できるものと期待されている。多糖類の化学的修飾に関する論文は数多く、私たちもこれまで多糖類の化学修飾のみならずその生物学的作用に関して検討してきた(構造-活性相関、SAR)。本論文では天然および化学修飾した多糖類の構造活性相関について最近の結果を示す。
Toshihiko Toida, Amornrut Chaidedgumjorn, Robert J. Linhardt   +2 more
openaire   +2 more sources

Beyond PEGylation: Archaeal Lipids for Long‐Circulating Liposomes

Advanced NanoBiomed Research, EarlyView.
Archaeal lipid‐based liposomes, particularly those containing caldarchaeol (GDGT), were found to significantly prolong the circulation time of vancomycin in rats, matching the pharmacokinetic properties of PEGylated systems. These findings suggest archaeal lipids as promising non‐PEG excipients for parenteral applications to minimize drug clearance ...
Viktor Sedlmayr, Andreas D. Meid, Eric Mühlberg, Manuel Ben Böhmann, Julian Quehenberger, David Wurm, Mikko Gynther, Oliver Spadiut, Gert Fricker, Philipp Uhl   +9 more
wiley   +1 more source

Evaluation of Sulfated Polysaccharides from the Brown Seaweed Dictyopteris Justii as Antioxidant Agents and as Inhibitors of the Formation of Calcium Oxalate Crystals

Molecules, 2013
Oxalate crystals and other types of crystals are the cause of urolithiasis, and these are related to oxidative stress. The search for new compounds with antioxidant qualities and inhibitors of these crystal formations is therefore necessary.
Karoline Rachel Teodosio Melo, Rafael Barros Gomes Camara, Moacir Fernandes Queiroz, Arthur Anthunes Jacome Vidal, Camila Renata Machado Lima, Raniere Fagundes Melo-Silveira, Jailma Almeida-Lima, Hugo Alexandre Oliveira Rocha   +7 more
doaj   +1 more source

Genome Analysis of Planctomycetes Inhabiting Blades of the Red Alga [PDF]

, 2016
Porphyra is a macrophytic red alga of the Bangiales that is important ecologically and economically. We describe the genomes of three bacteria in the phylum Planctomycetes (designated P1, P2 and P3) that were isolated from blades of Porphyra umbilicalis (
A Stamatakis, Arthur R. Grossman, B Kloareg, C Burke, C Jenkins, C Jogler, CE Wegner, CJ Gobler, D Ghosh, D Rentsch, DL Hatfield, E Alm, E Kazamia, ES Arner, F Goecke, FO Glockner, G Barbeyron, G Correc, G Levican, G Michel, G Michel, GM Preston, H Romero, HP Harding, J Allouch, J Allouch, J Bondoso, J Waring, JA Vorholt, JA Vorholt, Jane Grimwood, Jay W. Kim, Jean-François Pombert, Jeremy Schmutz, Jerry Jenkins, JH Hehemann, JH Hehemann, JH Hehemann, JH Skerratt, JL Rosner, JM Sieburth, John W. Stiller, JW Stiller, K Tait, Konstantinos Mavromatis, Kurt LaButti, L Fries, L Johansson, L Provasoli, L Puerto-Galan, LN Miranda, LS Mukai, M Jam, M Magrane, M Spoerner, M Toesch, Mansi Chovatia, Matt Nolan, Matthew Zane, MM Bengtsson, N Fernandes, NA Blouin, NA Blouin, OI Nedashkovskaya, OM Lage, P Lu, Q Zhang, R Pushker, R Santarella-Mellwig, R Santarella-Mellwig, S Arbogast, S Gromer, S Hou, S Kraan, Simon Prochnik, SR Hanson, SR Longford, Susan H. Brawley, T Barbeyron, T Barbeyron, T Dierks, T Lachnit, T Woyke, TJ Treangen, V Hofstetter, Y Matsuo, Y Matsuo, Y Zhang, ZA Popper   +88 more
core   +4 more sources

Induction of G1-phase cell cycle arrest and apoptosis pathway in MDA-MB-231 human breast cancer cells by sulfated polysaccharide extracted from Laurencia papillosa

Cancer Cell International, 2016
Marine algae consumption is linked to law cancer incidences in countries that traditionally consume marine products. Hence, Phytochemicals are considered as potential chemo-preventive and chemotherapeutic agents against cancer.
Hossam Murad, Mohammad Hawat, Adnan M. Ekhtiar, Abdulmunim Aljapawe, A. Abbas, Hussein Darwish, Oula Sbenati, A. Ghannam   +7 more
semanticscholar   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Research Progress on Immune Regulation Activities of Marine Sulfate Polysaccharides

Shipin gongye ke-ji
With changes in modern lifestyles, weakened immunity becomes a health problem for an increasing number of people. The development of natural active products with immunomodulatory activity becomes a popular research topic.
Qiuyu CHEN, Ran ZHAO, Meishan MENG, Xinyu DOU, Biyi CHEN, Qiancheng ZHAO, Ying LI   +6 more
doaj   +1 more source

Heparin insolubilized with crosslinking agent [PDF]

, 1969
New plastic compositions, involving the systhesis of a polymeric system containing heparin insolubilized with crosslinking agents, show appreciable promise in human body implant ...
Rembaum, A.
core   +1 more source

A Metagenome‐Assembled Genome Catalog From the Global Ruminant Microbiomes

Animal Research and One Health, EarlyView.
The Ruminant Gastrointestinal MAG Catalog (RGMC) is a comprehensive global resource offering 40,812 strain‐level genomes across 53 bacterial and 4 archaeal classes. It greatly surpasses prior efforts in scale and diversity, serving as an essential foundation for research in ruminant nutrition, microbial function, and methane mitigation.
Shizhe Zhang, Qiushuang Li, Bingzi Ouyang, Wenxing Wang, Xiang Zhou, Xiumin Zhang, Rong Wang, Zhiliang Tan, Min Wang   +8 more
wiley   +1 more source