Results 211 to 220 of about 11,612 (262)

Sulfated polysaccharides and their anticoagulant activity: A review

Applied Biochemistry and Microbiology, 2010
Published data on the sulfated polysaccharides of various origins that display an anticoagulant activity are summarized and analyzed. The methods used for producing semisynthetic derivatives are considered. A key role of the polysaccharide structure in the mechanisms of specific interaction with various blood plasma proteinases is discussed.
N M, Mestechkina, V D, Shcherbukhin
openaire   +2 more sources

Anticoagulant properties of semisynthetic polysaccharide sulfates

Thrombosis Research, 1991
Several naturally occurring polysaccharides were purified and subsequently sulfated by chlorosulfonic acid-pyridine complex. These were isolated as the sodium salt and further purified by ECTEOLA cellulose chromatography. Anticoagulant properties of the sulfated polysaccharides were compared with commercial heparin by measuring their in vitro effects ...
V M, Doctor, D, Lewis, M, Coleman, M T, Kemp, E, Marbley, V, Sauls   +5 more
openaire   +2 more sources

Modification of lymphocyte migration by sulfated polysaccharides

European Journal of Immunology, 1986
AbstractThe role of sulfated polysaccharides in lymphocyte migration has been analyzed in vivo using lymphocytes labeled with an intracellular DNA‐binding fluorochrome Hoechst 33342. The influence of a panel of sulfated polysaccharides on entry (by injecting the sulfated polysaccharide prior to the labeled cells) and displacement from lymphoid organs ...
M, Brenan, C R, Parish
openaire   +2 more sources

Anti-inflammatory action of sulfated polysaccharides

Biochemical Pharmacology, 1969
Abstract A number of sulfated polymers: pentosan polysulfate, polyvinyl sulfate, polyethylene sulfonate, cellulose sulfate, dextran sulfate, sulfate amylopectin, in the same way as carragenin, degraded carragenin and dextran, produce edema in the rat's paw by local injection, to release kinins from fresh guinea pig and rat's plasma (in vitro) and to ...
M, Rocha e Silva, R Q, Cavalcanti, M L, Reis   +2 more
openaire   +2 more sources

Sulfated Seaweed Polysaccharides as Antiviral Agents

Current Medicinal Chemistry, 2004
Several sulfated seaweed polysaccharides show high antiviral activity against enveloped viruses, including important human pathogens such as human immunodeficiency virus, herpes simplex virus, human cytomegalovirus, dengue virus and respiratory syncytial virus. They can be obtained in major amounts and at low costs, have low toxicity and in some cases,
Elsa B, Damonte, María C, Matulewicz, Alberto S, Cerezo   +2 more
openaire   +2 more sources

Determination of the positions of the sulfate groups in sulfated polysaccharides

Chemistry of Natural Compounds, 1976
1. The possibility has been shown of using a method proposed by us previously to determine the positions of the sulfate groups in sulfated polysaccharides. 2. The positions of the sulfate groups in the following sulfated polysaccharides have been determined: fucan and pelvecyan fromPelvetia wrightii and sargassan fromSargassum pallidum.
A. F. Pavlenko, N. I. Belogortseva, A. I. Kalinovskii, Yu. S. Ovodov   +3 more
openaire   +1 more source

Astragalus polysaccharide and sulfated epimedium polysaccharide synergistically resist the immunosuppression

Carbohydrate Polymers, 2012
The immunoenhancement of compound polysaccharides, APS-sEPS composed with astragalus polysaccharide (APS) and sulfated epimedium polysaccharide (sEPS), was observed in immunosuppressed model chicken induced by cyclophosphamide (Cy). 11-day-old chickens were injected with Cy once a day for three successive days except vaccine control group.
Liwei, Guo, Jiaguo, Liu, Yuanliang, Hu, Deyun, Wang, Zhizhong, Li, Jing, Zhang, Tao, Qin, Xu, Liu, Cui, Liu, Xiaojuan, Zhao, Yun Peng, Fan, Guocai, Han, The Luong, Nguyen   +12 more
openaire   +2 more sources

Synthetic photocrosslinkable polysaccharide sulfates

European Polymer Journal, 2010
Abstract Photoactive derivatives of dextran and pullulan with high degree of substitution were prepared by an efficient and mild esterification of the biopolymers with [(4-methyl-2-oxo-2H-chromen-7-yl)oxy] acetic acid via in situ activation of the carboxylic acid with N,N′- carbonyldiimidazole.
Holger Wondraczek, Annett Pfeifer, Thomas Heinze   +2 more
openaire   +1 more source

Procoagulant Activity of Sulfated Polysaccharides

Blood, 2010
Abstract Abstract 4419 BAX513, a Laminaria japonica-derived fucoidan and other non-anticoagulant sulfated polysaccharides (NASPs) have been shown to improve clotting in FVIII- and FIX-deficient plasma (Liu et al. Thromb Haemost 2006; 95:68).
Michael Dockal, Sabine Knappe, Erwin Panholzer, Michael Palige, Hartmut J. Ehrlich, Friedrich Scheiflinger   +5 more
openaire   +1 more source

Adjuvanticity of compound astragalus polysaccharide and sulfated epimedium polysaccharide per os

International Journal of Biological Macromolecules, 2013
On the basis of previous researches, compound astragalus polysaccharide (APS) and sulfated epimedium polysaccharide (sEPS) oral liquid (AEO) was prepared. Three hundred and twenty 14-day-old chickens were randomly assigned into eight groups and vaccinated with ND vaccine except for blank control (BC) group, repeated vaccination at 28 days old.
Xingying, Chen, Xiaolan, Chen, Shulei, Qiu, Yuanliang, Hu, Deyun, Wang, Xu, Liu, Xiaojuan, Zhao, Cui, Liu, Xinghui, Chen   +8 more
openaire   +2 more sources