Results 11 to 20 of about 5,159 (209)

Compromised Myelin and Axonal Molecular Organization Following Adult-Onset Sulfatide Depletion

Biomedicines, 2023
3-O-sulfogalactosylceramide, or sulfatide, is a prominent myelin glycosphingolipid reduced in the normal appearing white matter (NAWM) in Multiple Sclerosis (MS), indicating that sulfatide reduction precedes demyelination.
Juan Pablo Palavicini, Elizabeth Dustin, Xianlin Han   +2 more
exaly   +4 more sources

Sulfatide Binds to Influenza B Virus and Enhances Viral Replication. [PDF]

Viruses
Seasonal influenza epidemics caused by influenza A viruses (IAV) and influenza B viruses (IBV) pose a substantial public health burden. Despite the significant impact of IBV, its restricted host range and the absence of documented pandemics have resulted
Kurebayashi Y, Wakabayashi Y, Takahashi T, Sakakibara K, Takahashi S, Minami A, Suzuki T, Takeuchi H.   +7 more
europepmc   +3 more sources

Immunogenicity of sulfatide [PDF]

Immunochemistry, 1977
The present study deals with the immunogenicity of sulfatide. Despite its acidic character, we succeeded in raising high titer antibodies. The most effective immunization procedure involved repeated intravenous injections of a mixture of sulfatide ...
C Jacque, B Zalc, Zalc, B., Dupouey, P., Jacque, C., N.S Radin, P Dupouey, Radin, Norman S.   +7 more
core   +5 more sources

Potential of serum sulfatide levels as a marker for classification and disease activity in lupus nephritis. [PDF]

Front Immunol
IntroductionLupus nephritis (LN) is a severe complication of systemic lupus erythematosus, often leading to end-stage kidney disease. Serum sulfatide levels are linked to severe kidney vasculitis.
Yamaka K, Aomura D, Harada M, Nakajima T, Nimura T, Hashimoto K, Tanaka N, Kamijo Y.   +7 more
europepmc   +4 more sources

Sulfatide in health and disease. The evaluation of sulfatide in cerebrospinal fluid as a possible biomarker for neurodegeneration [PDF]

Molecular and Cellular Neuroscience, 2021
Sulfatide (3-O-sulfogalactosylceramide, SM4) is a glycosphingolipid, highly multifunctional and particularly enriched in the myelin sheath of neurons.
Blomqvist, M, Zetterberg, H, Månsson, J-E, Blennow, K   +3 more
core   +6 more sources

The repertoire of protein-sulfatide interactions reveal distinct modes of sulfatide recognition

Frontiers in Molecular Biosciences, 2022
Sulfatide is an abundant glycosphingolipid in the mammalian nervous system, kidney, trachea, gastrointestinal tract, spleen, and pancreas and is found in low levels in other tissues.
Daniel G. S Capelluto
doaj   +3 more sources

Sulfatide Preserves Insulin Crystals Not by Being Integrated in the Lattice but by Stabilizing Their Surface [PDF]

Journal of Diabetes Research, 2016
Background. Sulfatide is known to chaperone insulin crystallization within the pancreatic beta cell, but it is not known if this results from sulfatide being integrated inside the crystal structure or by binding the surface of the crystal.
Karsten Buschard, Austin W. Bracey, Daniel L. McElroy, Andrew T. Magis, Thomas Osterbye, Mark A. Atkinson, Kate M. Bailey, Amanda L. Posgai, David A. Ostrov   +8 more
doaj   +2 more sources

Sulfatide regulates caspase-3-independent apoptosis of influenza A virus through viral PB1-F2 protein. [PDF]

PLoS ONE, 2013
Influenza A virus (IAV) generally causes caspase-dependent apoptosis based on caspase-3 activation, resulting in nuclear export of newly synthesized viral nucleoprotein (NP) and elevated virus replication.
Tadanobu Takahashi, Masahiro Takaguchi, Tatsuya Kawakami, Takashi Suzuki   +3 more
doaj   +2 more sources

Fecal sulfatide as a non-invasive biomarker for predicting coronary heart disease. [PDF]

Eur J Med Res
Objectives The study aimed to investigate a non-invasive biomarker for predicting coronary heart disease by analyzing fecal sulfatide levels. Methods A retrospective study was conducted on 593 patients with coronary heart disease, divided into acute ...
Hu R, Li Y, Xue K, Hu X, Guo R, Guo H, Li G.   +6 more
europepmc   +2 more sources

Effects of sulfatide on peripheral nerves in metachromatic leukodystrophy

Annals of Clinical and Translational Neurology
Objective To evaluate the longitudinal correlations between sulfatide/lysosulfatide levels and central and peripheral nervous system function in children with metachromatic leukodystrophy (MLD) and to explore the impact of intravenous recombinant human ...
Mohamed H. Farah, Christine í Dali, Samuel Groeschel, Mihai Moldovan, David A. H. Whiteman, C. J. Malanga, Ingeborg Krägeloh‐Mann, Jing Li, Norman Barton, Christian Krarup   +9 more
doaj   +2 more sources