Results 31 to 40 of about 5,159 (209)
Differential binding patterns of anti-sulfatide antibodies to glial membranes [PDF]
, 2018 Sulfatide is a major glycosphingolipid in myelin and a target for autoantibodies in autoimmune neuropathies. However neuropathy disease models have not been widely established, in part because currently available monoclonal antibodies to sulfatide may ...
Dawn Gourlay +17 more
core +1 more source
The C24:0 Sulfatide Isoform as an Important Molecule in Type 1 Diabetes
Frontiers in Bioscience-Landmark, 2022 Particular molecules play pivotal roles in the pathogenesis of many autoimmune diseases. We suggest that the C24:0 sulfatide isoform may influence the development of type 1 diabetes (T1D).
Karsten Buschard, Julie C Antvorskov
doaj +1 more source
Self-glycolipids modulate dendritic cells changing the cytokine profiles of committed autoreactive T cells. [PDF]
PLoS ONE, 2012 The impact of glycolipids of non-mammalian origin on autoimmune inflammation has become widely recognized. Here we report that the naturally occurring mammalian glycolipids, sulfatide and β-GalCer, affect the differentiation and the quality of antigen ...
Karsten Buschard +3 more
doaj +1 more source
The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide
Cells, 2021 Sulfatide synthesis in the human renal cancer cell line SMKT-R3 was strongly inhibited in the presence of low µM concentrations of AG-205, a progesterone receptor membrane component 1 (PGRMC1) antagonist.
Lihua Wang-Eckhardt +2 more
doaj +1 more source
Antigen-presentation of non-peptidic antigens lipid trafficking and loading [PDF]
, 2010 T cells recognize a broad variety of antigens, including peptides, lipids and non-peptidic phosphorylated metabolites. Clarification of the rules rendering non-peptidic molecules immunogenic is essential to understand and to influence the reactions of ...
Cavallari, Marco F.
core +1 more source
Synthesis and turnover of cerebroside sulfate of myelin in adult and developing rat brain
Journal of Lipid Research, 1974 The turnover of cerebroside sulfate (sulfatide) was followed in both microsomal and myelin fractions of developing and adult rat brains after an intracerebral injection of Na235SO4.
Firoze B. Jungalwala
doaj +1 more source
Regulation of integrin αV subunit expression by sulfatide in hepatocellular carcinoma cells
Journal of Lipid Research, 2013 Integrin is important in migration and metastasis of tumor cells. Changes of integrin expression and distribution will cause an alteration of cellular adhesion and migration behaviors.
Wei Wu +10 more
doaj +1 more source
Neurobiology of Disease, 2004 Metachromatic leukodystrophy (MLD) is a lysosomal lipid storage disease caused by arylsulfatase A deficiency. In MLD patients the sphingolipid sulfatide increasingly accumulates leading to progressive demyelination.
K Saravanan +7 more
doaj +1 more source
The biological role of sulfatides
Postępy Higieny i Medycyny Doświadczalnej, 2016 Sulfatides (3-O-sulfogalactosylceramides, sulfated galactocerebrosides, SM4) are esters of sulfuric acid with galactosylceramides. These acidic glycosphingolipids, present at the external leaflet of the plasma membrane, are synthesized by a variety of mammalian cells.
Jarosław, Suchański, Maciej, Ugorski
openaire +2 more sources
Role of sulfatide in normal and pathological cells and tissues
Journal of Lipid Research, 2012 Sulfatide is 3-O-sulfogalactosylceramide that is synthesized by two transferases (ceramide galactosyltransferase and cerebroside sulfotransferase) from ceramide and is specifically degraded by a sulfatase (arylsulfatase A). Sulfatide is a multifunctional
Tadanobu Takahashi, Takashi Suzuki
doaj +1 more source