Results 91 to 100 of about 13,197 (261)

Structure of the heterotrimeric PCNA fromSulfolobus solfataricus [PDF]

Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2006
PCNA is a ring-shaped protein that encircles DNA, providing a platform for the association of a wide variety of DNA-processing enzymes that utilize the PCNA sliding clamp to maintain proximity to their DNA substrates. PCNA is a homotrimer in eukaryotes, but a heterotrimer in crenarchaea such as Sulfolobus solfataricus.
Williams, Gareth J., Johnson, Kenneth, Rudolf, Jana, McMahon, Stephen A., Carter, Lester, Oke, Muse, Liu, Huanting, Taylor, Garry L., White, Malcolm F., Naismith, James H.   +9 more
openaire   +2 more sources

Distinct Patterns of Antibiotic Sensitivities in Ammonia‐Oxidising Archaea

Environmental Microbiology, Volume 27, Issue 3, March 2025.
Antibiotic sensitivity varies between different strains of ammonia‐oxidising archaea. The results of this study will be useful for selective enrichment and development of a genetic system for ammonia‐oxidising archaea. ABSTRACT Ammonia‐oxidising archaea (AOA) are important microorganisms contributing towards the nitrogen flux in the environment. Unlike
Timothy Klein, Logan H. Hodgskiss, Max Dreer, J. Colin Murrell, Matthew I. Hutchings, Christa Schleper, Laura E. Lehtovirta‐Morley   +6 more
wiley   +1 more source

Control of cyclic oligoadenylate synthesis in a type III CRISPR system

eLife, 2018
The CRISPR system for prokaryotic adaptive immunity provides RNA-mediated protection from viruses and mobile genetic elements. When viral RNA transcripts are detected, type III systems adopt an activated state that licenses DNA interference and synthesis
Christophe Rouillon, Januka S Athukoralage, Shirley Graham, Sabine Grüschow, Malcolm F White   +4 more
doaj   +1 more source

Analysis of nucleotide insertion opposite urea and translesion synthesis across urea by DNA polymerases

Genes and Environment, 2022
Urea (Ua) is produced in DNA as the result of oxidative damage to thymine and guanine. It was previously reported that Klenow fragment (Kf) exo− incorporated dATP opposite Ua, and that DNA polymerase β was blocked by Ua.
Taishu Kawada, Katsuhito Kino, Kyousuke Tokorodani, Ryuto Anabuki, Masayuki Morikawa, Takanobu Kobayashi, Kazuaki Ohara, Takayuki Ohshima, Hiroshi Miyazawa   +8 more
doaj   +1 more source

Nucleases: From Primitive Immune Defenders to Modern Biotechnology Tools

Immunology, Volume 174, Issue 3, Page 279-286, March 2025.
The evolution of nucleases is a remarkable journey, starting as primitive bacterial defenders against bacteriophages. Over time, nucleases have adapted to specialised roles within the immune systems of all forms of life, culminating in humans, where DNases and RNases serve as key components of the immune system.
Frank J. Hernandez
wiley   +1 more source

N-glycosylation in the thermoacidophilic archaeon Sulfolobus acidocaldarius involves a short dolichol pyrophosphate carrier [PDF]

, 2016
N-glycosylation is a post-translational modification that occurs across evolution. In the thermoacidophilic archaea Sulfolobus acidocaldarius, glycoproteins are modified by an N-linked tribranched hexasaccharide reminiscent of the N-glycans assembled in ...
Abu-Qarn, Aebi, Albers, Bligh, Brock, Burda, Calo, Chang, Cohen-Rosenzweig, Eichler, Guan, Guan, Guan, Gulik, Hartley, Hartmann, Jarrell, Jones, Kaminski, Kandiba, Kelleher, Kuntz, Larkin, Lechner, Lehrman, Mescher, Meyer, Meyer, Meyer, Nothaft, Palmieri, Peyfoon, Shams-Eldin, Swiezewska, Szymanski, Taguchi, Wagner, Weerapana, Zahringer   +38 more
core   +3 more sources

Identification, characterization and classification of prokaryotic nucleoid‐associated proteins

Molecular Microbiology, Volume 123, Issue 3, Page 206-217, March 2025.
Nucleoid‐associated proteins (NAPs) structure DNA by either bending, wrapping, bridging, or forming protein filaments on the DNA. We review newly identified NAPs and provide a list of simple biochemical assays to study the DNA‐structuring properties of novel NAPs. Abstract Common throughout life is the need to compact and organize the genome.
Samuel Schwab, Remus T. Dame
wiley   +1 more source

Hyperthermophilic endoglucanase for in planta lignocellulose conversion

Biotechnology for Biofuels, 2012
Background The enzymatic conversion of lignocellulosic plant biomass into fermentable sugars is a crucial step in the sustainable and environmentally friendly production of biofuels.
Klose Holger, Röder Juliane, Girfoglio Michele, Fischer Rainer, Commandeur Ulrich   +4 more
doaj   +1 more source

Chromatin and gene regulation in archaea

Molecular Microbiology, Volume 123, Issue 3, Page 218-231, March 2025.
Recent data from diverse archaea with different repertoires of nucleoid‐associated proteins show a common genome‐wide chromatin organisation where chromatin maintains access to gene promoters independently of transcription activity. Abstract The chromatinisation of DNA by nucleoid‐associated proteins (NAPs) in archaea ‘formats’ the genome structure in ...
Fabian Blombach, Finn Werner
wiley   +1 more source

Rad54: the Swiss Army knife of homologous recombination? [PDF]

, 2006
Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of genetic information between homologous or near homologous (homeologous) DNA sequences. During meiosis it ensures proper chromosome segregation in the first division.
Heyer, Wolf-Dietrich, Li, Xuan, Rolfsmeier, Michael, Zhang, Xiao-Ping   +3 more
core   +2 more sources