Removal of concentrated sulfamethazine by acclimatized aerobic sludge and possible metabolic products [PDF]
This article examined the biological removal of high concentrated sulfamethazine (SMZ) antibiotics by the acclimatized activated sludge in lab-scale SBRs system.
Na Yang+3 more
doaj +2 more sources
Preclinical Evaluation of Ureidosulfamate Carbonic Anhydrase IX/XII Inhibitors in the Treatment of Cancers [PDF]
Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues. Upregulation of the CAIX/XII isoforms is associated with hypoxic tumours and clinically linked with malignant progression, treatment ...
Gieling, Roben, Williams, Kaye J.
core +2 more sources
Genetically designed biomolecular capping system for mesoporous silica nanoparticles enables receptor-mediated cell uptake and controlled drug release [PDF]
Effective and controlled drug delivery systems with on-demand release and targeting abilities have received enormous attention for biomedical applications. Here, we describe a novel enzyme-based cap system for mesoporous silica nanoparticles (MSNs) that is directly combined with a targeting ligand via bio-orthogonal click chemistry.
arxiv +1 more source
Disseminated Nocardia cyriacigeorgia causing pancreatitis in a haploidentical stem cell transplant recipient. [PDF]
We report the first published case of acute pancreatitis secondary to disseminated nocardiosis in a hematopoietic stem cell transplant (HSCT) recipient on chronic immunosuppression for graft-versus-host disease (GVHD).
Chen, MD, Jason+4 more
core +3 more sources
In the title compound, C9H8N2O2S, the sulfamoyl -NH2 group is involved in inter-molecular hydrogen bonding with the sulfonamide O and quinoline N atoms. In the crystal, mol-ecules are linked into dimers via pairs of N-H⋯N hydrogen bonds, forming an R 2 (2)(10) motif.
Krzysztof Marciniec+3 more
openaire +3 more sources
Transfer of Sulfamethazine from Contaminated Beeswax to Honey [PDF]
A liquid chromatographic tandem mass spectrometric method for the determination of sulfa drugs in beeswax was developed. When performing residue control on beeswax intended for the fabrication of wax foundations, residues of sulfonamides were found.
Daeseleire, Els+3 more
core +1 more source
Universal Reagent for Mild and Stereospecific Nucleophilic Substitution of Alcohols with Amines
A user‐friendly, shelf‐stable protonated betaine reagent (BEHT triflate), derived from Mitsunobu reagents, has been developed to enable the direct displacement of alcohols using primary and secondary amines as nucleophiles. The reaction with chiral, non‐racemic secondary alcohols proceeds with inversion of configuration, allowing for one‐step formation
William S. Bechara+7 more
wiley +2 more sources
Three Dimensional Quantitative Structure-Activity Relationships of Sulfonamides Binding Monoclonal Antibody by Comparative Molecular Field Analysis [PDF]
The three-dimensional quantitative structure-activity relationship (3D-QSAR) model of sulfonamide analogs binding a monoclonal antibody (MabSMR) produced against sulfamerazine, was carried out by comparative molecular field analysis (CoMFA).
Congming Wu+8 more
core +1 more source
Salt‐Compact Albumin as a New Pure Protein‐based Biomaterials: From Design to In Vivo Studies
A new class of materials built entirely of native albumin protein is designed using a simple protocol based on salt‐assisted compaction, breaking with current crosslinking strategies. This green process leads, surprisingly, to water‐insoluble handable materials with high preservation of their native protein structures and Young's modulus close to that ...
Eya Aloui+19 more
wiley +1 more source
Steady state free precession (SSFP) – Complete Reduction to Amplitude Frequency Tables (CRAFT) not only improves sensitivity, resolution and number of signals detected by NMR but can also dramatically reduce experiment times. This powerful approach unlocks the potential of NMR as a discovery tool, enabling unprecedented detection of fluorinated ...
Jeremy R. Gauthier+10 more
wiley +2 more sources