Results 181 to 190 of about 77,413 (299)

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Dual conformational emission and vibrational coherence in a sulfone-embedded narrowband emitter. [PDF]

Chem Sci
Jiang S, He Y, Yang GX, Pullerits T, Su SJ.   +4 more
europepmc   +1 more source

The plasticisation model of dye diffusion: Part 8

Coloration Technology, EarlyView.
Abstract Re‐evaluation using the Williams–Landel–Ferry equation, of exhaustion/rate of dyeing/fixation data previously reported for and acid dye, natural dye and two reactive dyes on three different types of silk substrate revealed that thermally activated dye diffusivity is governed by the thermally regulated structural relaxation times of the ...
Stephen M. Burkinshaw
wiley   +1 more source

Strategically significant synthesis of conjugated porous organic polymers via retro diazotization chemistry. [PDF]

Nat Commun
Ozer MS, Eroglu Z, Koyuncu S, Metin O.
europepmc   +1 more source

Synthesis of (E)‐β‐SF5‐Styrenes via a Heck Reaction of in situ Generated Vinylsulfur Pentafluoride†

Chinese Journal of Chemistry, Volume 44, Issue 11, Page 1823-1827, 1 June 2026.
A Heck cross‐coupling reaction between aryl(hetero)iodides and in situ generated vinylsulfur pentafluoride is reported. This reaction provides β‐SF5‐styrenes in one‐step as a single (E)‐stereoisomer and tolerates a broad range of functional groups. Comprehensive Summary The synthesis of (E)‐(1‐alken‐1‐yl)pentafluoro‐λ6‐sulfanes, a valuable class of ...
Nicolas DeGrâce, Jean‐François Paquin   +1 more
wiley   +1 more source

Pyridine-boryl radical mediated synthesis of quinolines <i>via</i> α-amino radical formation and intramolecular alkenyl sulfone trapping.

Org Chem Front
Valderrama-Callejón R, Alonso I, Gómez S, Jiménez D, Dorado-Briones G, Vargas EL, Tortosa M, Cid MB.   +7 more
europepmc   +1 more source

Nickel-catalyzed divergent sulfonations of propargylic carbonate. [PDF]

Nat Commun
Gu W, He Z, Wang H, Peng L, Guo C.
europepmc   +1 more source

Iron‐Mediated Electrochemical Cyclopropanation of Borodiiodomethane with Alkenes†

Chinese Journal of Chemistry, Volume 44, Issue 10, Page 1565-1572, 15 May 2026.
This work describes an electrochemical iron‐mediated cyclopropanation of borodiiodomethane with alkenes, resulting in the formation of boro‐substituted cyclopropanes. A key feature of this study is the unexpected discovery that the cathodically generated iron ion coordinates with a biquinoline ligand in situ, facilitating the electrochemical ...
Jie Li, Yingying Pan, Xin Wang, Xuefeng Tan   +3 more
wiley   +1 more source

Organo-catalyzed deamination of polystyrene sulfonamide for diverse post-polymerization modification of styrenic polymers.

Polym Chem
Shrestha T, Nguyen DM, Goehrig H, Damani VS, Quinn CM, Kayser LV.   +5 more
europepmc   +1 more source

Evaluation of Passive Air Sampling for Monitoring Current-Use Pesticide Pollution near Large-Scale Banana Plantations in Costa Rica. [PDF]

Environ Sci Technol
Solano Díaz K, Ruepert C, Ramírez Quesada MM, Hoppin JA, Wania F, van Wendel de Joode B.   +5 more
europepmc   +1 more source