Results 211 to 220 of about 57,978 (298)

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Transfer of veterinary parasiticides from the fur lining bird's nest to eggs and chicks. [PDF]

Environ Sci Pollut Res Int
Tassin-de-Montaigu C, Glauser G, Guinchard S, Goulson D.   +3 more
europepmc   +1 more source

The plasticisation model of dye diffusion: Part 8

Coloration Technology, EarlyView.
Abstract Re‐evaluation using the Williams–Landel–Ferry equation, of exhaustion/rate of dyeing/fixation data previously reported for and acid dye, natural dye and two reactive dyes on three different types of silk substrate revealed that thermally activated dye diffusivity is governed by the thermally regulated structural relaxation times of the ...
Stephen M. Burkinshaw
wiley   +1 more source

Machine learning-based QSAR and molecular modeling of phytocompounds in <i>Barleria buxifolia L.</i> as a potential aldose reductase inhibitor. [PDF]

Front Bioinform
Dev RR, Lalu AC, Zarin S, Joseph BB, Raju R, Jayanandan A, Thekkan S.   +6 more
europepmc   +1 more source

Four Haylages, One Metabonome: Defining Diet Driven Metabolic Shifts in Ponies

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Haylage is widely fed to all categories of stabled horses across Europe and New Zealand. Haylage can vary from high energy nutrient dense forage to low energy highly fibrous fodder, yet little is known about the impact different haylages have on metabolism in horses.
Meriel Moore‐Colyer, Pat Harris, Simon Daniels   +2 more
wiley   +1 more source

Direct adverse effects of fipronil sulfone, diisopentyl phthalate and disperse red 60 on zebrafish hepatocytes. [PDF]

Toxicol Rep
Leite BA, de Oliveira DP, Unniappan S.
europepmc   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Thiophene π-Bridge Engineering for Boosting Photocatalytic H₂ Evolution of Dioxythiophene-Based D-A-π-A Conjugated Polymers Without Extraneous Noble Metal Loading. [PDF]

Molecules
Tian G, Zhao H, Zhang J, Song S, Zhang L, Wu H, Wang F, Li J, Guo J, Yi Q.   +9 more
europepmc   +1 more source

Sulfonation

Journal of Synthetic Organic Chemistry, Japan, 1951
openaire   +2 more sources

Renal and Functional Vulnerability in Hansen Disease: A Framework for Chronic Infectious Disability in Endemic Settings

Tropical Medicine &International Health, EarlyView.
ABSTRACT Objectives Hansen disease is a neglected infectious disease associated with reactional inflammation, neuropathy and long‐term disability. Renal involvement and sarcopenia have been described separately, but their clinical coexistence has received limited attention. This review examines evidence for a hypothesised renal–functional vulnerability
Kleberson de Oliveira, Lucas Maciel de Almeida Corrêa, Isabela Malerba Pinheiro, Alexandre de Assis Barbosa, Maria Eduarda Castro Gonçalves, Lara Lucena Fernandes Filgueiras, Lara Reis Gomes de Mello Queiroz   +6 more
wiley   +1 more source