Results 91 to 100 of about 373 (187)

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

Manganese-catalyzed cyclopropanation of allylic alcohols with sulfones

Nature Communications
Cyclopropanes are among the most important structural units in natural products, pharmaceuticals, and agrochemicals. Herein, we report a manganese-catalyzed cyclopropanation of allylic alcohols with sulfones as carbene alternative precursors via a ...
Ke Yu, Qin Nie, Qianjin Chen, Weiping Liu   +3 more
doaj   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

Zinc Promoted Cross‐Electrophile Sulfonylation to Access Alkyl–Alkyl Sulfones

Advanced Science
The transition metal‐catalyzed multi‐component cross‐electrophile sulfonylation, which incorporates SO2 as a linker within organic frameworks, has proven to be a powerful, efficient, and cost‐effective means of synthesizing challenging alkyl–alkyl ...
Zhuochen Wang, Rui Ma, Chang Gu, Xiaoqian He, Haiwei Shi, Ruopeng Bai, Renyi Shi   +6 more
doaj   +1 more source

Direct Synthesis of Allylic Sulfones via Hydrosulfonylation of 1,3-Dienes with Sulfinic Acids

Molecules
Catalyst- and additive-free reactions for synthesizing valuable organic compounds have garnered significant attention in the context of sustainable development.
Ke Guo, Shuaichen Zhang, Jing Zhang, Yu Ren, Xiaoqiang Chang, Peng Sun   +5 more
doaj   +1 more source

Metal Nanoparticles on Halloysite Applied in Stereoselective Hydrogenation of Tetrasubstituted Alkenes

Chemistry – A European Journal, EarlyView.
Composite materials based on metal nanoparticles supported on a naturally occurring nanotubular clay, halloysite (HAL), led to the diastereoselective hydrogenation of tetra‐substituted alkenes under relatively smooth conditions, mainly oxazolidinone‐based heterocycles.
Rosa Pich, Gabriel Domínguez, Leo Westrey, Pierre Lavedan, Sonia Mallet‐Ladeira, Jérôme Esvan, Jean‐François Lahitte, Jean‐Christophe Remigy, Daniel Pla, Montserrat Gómez   +9 more
wiley   +1 more source

Iridium‐Catalyzed Linear‐Selective sp3 C−H Alkylation of N‐Methylamides Using Alkenes Enabled by Diphosphite Ligands

Chemistry – A European Journal, EarlyView.
An iridium‐catalyzed linear‐selective sp3 C─H alkylation of N‐methylamides with alkenes is described. This method tolerates various N‐methylacetamide derivatives and has a broad alkene scope. Mechanistic studies were also conducted. Internal alkenes can also be used through in situ consecutive alkene isomerization.
Haluhi Takahashi, Takanori Shibata
wiley   +1 more source

Iron‐Mediated Electrochemical Cyclopropanation of Borodiiodomethane with Alkenes†

Chinese Journal of Chemistry, EarlyView.
This work describes an electrochemical iron‐mediated cyclopropanation of borodiiodomethane with alkenes, resulting in the formation of boro‐substituted cyclopropanes. A key feature of this study is the unexpected discovery that the cathodically generated iron ion coordinates with a biquinoline ligand in situ, facilitating the electrochemical ...
Jie Li, Yingying Pan, Xin Wang, Xuefeng Tan   +3 more
wiley   +1 more source

Synthesis of (E)‐β‐SF5‐Styrenes via a Heck Reaction of in situ Generated Vinylsulfur Pentafluoride†

Chinese Journal of Chemistry, EarlyView.
A Heck cross‐coupling reaction between aryl(hetero)iodides and in situ generated vinylsulfur pentafluoride is reported. This reaction provides β‐SF5‐styrenes in one‐step as a single (E)‐stereoisomer and tolerates a broad range of functional groups. Comprehensive Summary The synthesis of (E)‐(1‐alken‐1‐yl)pentafluoro‐λ6‐sulfanes, a valuable class of ...
Nicolas DeGrâce, Jean‐François Paquin   +1 more
wiley   +1 more source

Membrane Engineering for Battery Systems: Bridging Design Principles and Frontier Applications

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The review emphasizes membrane separators' role in battery performance and safety, covering redox flow, lithium‐ion, and solid‐state batteries. It reviews advances in membrane materials (e.g., polymer electrolytes, hybrid composites) and ion transport mechanisms, while addressing challenges like dendrite growth and crossover losses.
Xiaoqun Zhou, Justice Delali Akoto, Rui Tan, Jun Ma   +3 more
wiley   +1 more source