Results 31 to 40 of about 32,899 (265)
The gram-positive opportunistic bacterium Staphylococcus aureus is one of the most common causatives of a variety of diseases including skin and skin structure infection or nosocomial catheter-associated infections.
Irshad S. Sharafutdinov+14 more
doaj +1 more source
Can acyclic conformational control be achieved via a sulfur-fluorine gauche effect? [PDF]
The gauche conformation of the 1,2-difluoroethane motif is known to involve stabilising hyperconjugative interactions between donor (bonding, σC-H) and acceptor (antibonding, σ*C-F) orbitals.
Daniliuc, C+4 more
core +1 more source
Transient Sulfenic Acids in the Synthesis of Biologically Relevant Products
Sulfenic acids as small molecules are too unstable to be isolated and their transient nature offers the possibility to involve them in concerted processes that lead to the obtainment of functional groups such as sulfoxides, sulfones, and disulfides.
Anna Barattucci+4 more
doaj +1 more source
A highly efficient and eco-friendly method has been developed for the synthesis of allyl sulfones using Morita–Baylis–Hillman (MBH) adducts and thiosulfonates under mild conditions.
Angothu Shankar+2 more
doaj +1 more source
In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi. [PDF]
BackgroundCruzain, the major cysteine protease of Trypanosoma cruzi, is an essential enzyme for the parasite life cycle and has been validated as a viable target to treat Chagas' disease.
Brinen, Linda S+6 more
core +3 more sources
Synthesis of a New Chiral Pyrrolidine
The synthesis of a new chiral pyrrolidine has been performed using 2,3-O-isopropylidene-D-erythronolactol as a suitable starting material.
Pilar García+7 more
doaj +1 more source
Novel cruzain inhibitors for the treatment of Chagas' disease. [PDF]
The protozoan parasite Trypanosoma cruzi, the etiological agent of Chagas' disease, affects millions of individuals and continues to be an important global health concern.
Arkin, Michelle R+6 more
core +1 more source
Water-promoted C-S bond formation reactions
Despite the biological importance of sulfones, available synthetic methods usually involve toxic metals and reagents or harsh conditions. Here, the authors report an environmentally benign procedure for the metal-free carbon-sulfur bond formation of ...
Peizhong Xie+7 more
doaj +1 more source
Hydrophobic Polyelectrolytes in Better Polar Solvent. Structure and Chain Conformation as seen by Saxs and Sans [PDF]
We demonstrate in this paper the influence of solvent quality on the structure of the semi-dilute solution of a hydrophobic polyelectrolyte, partially sulfonated Poly-Styrene Sulfonate. Two solvents are used: (i) one mixture of water and an organic solvent: THF, which is also slightly polar; (ii) DMSO, a polar organic solvent.
arxiv +1 more source
Sequential curing of thiol-acetoacetate-acrylate thermosets by latent Michael addition reactions [PDF]
Thiol-acetoacetate-acrylate ternary dual-curing thermosets were prepared by a sequential process consisting of thiol-Michael addition to acrylates at room temperature followed by Michael addition of acetoacetates to acrylates at moderately elevated ...
Fernández Francos, Xavier+5 more
core +2 more sources