Results 141 to 150 of about 1,253,570 (258)

Pharmaco-topology of Sulfonylurea Receptors [PDF]

open access: yesJournal of Biological Chemistry, 2000
Andrey P. Babenko   +2 more
openaire   +1 more source

Cardiovascular preventive role of thiazolidinedione in patients with type 2 diabetes mellitus undergoing percutaneous coronary intervention

open access: yesJournal of Diabetes Investigation, EarlyView.
Among patients with type 2 diabetes undergoing percutaneous coronary intervention, thiazolidinedione use was independently associated with a significantly reduced risk of a composite of myocardial infarction, stroke, and all‐cause death, notably without an increased risk of admission for heart failure. ABSTRACT Background Thiazolidinediones (TZD) are a
Jinkwon Kim   +5 more
wiley   +1 more source

Serum‐derived microribonucleic acids as potential novel biomarkers for slowly progressive type 1 diabetes mellitus

open access: yesJournal of Diabetes Investigation, EarlyView.
This study evaluated serum miRNAs as biomarkers in adult patients with SPIDDM. Serum miRNAs were measured at the time of SPIDDM (probable) diagnosis, and miR‐150‐5p was inversely associated with CPI at the last outpatient visit, suggesting its potential utility for predicting subsequent insulin secretory decline.
Hideyuki Okuma   +4 more
wiley   +1 more source

Effects of esaxerenone add‐on therapy versus angiotensin II receptor blocker dose escalation on albuminuria and blood pressure in hypertensive patients with type 2 diabetes: An exploratory randomized study

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims Residual albuminuria remains a major clinical challenge in patients with type 2 diabetes mellitus and hypertension despite renin–angiotensin system inhibitor therapy. Esaxerenone, a selective nonsteroidal mineralocorticoid receptor antagonist, reduces albuminuria; however, its effects on oxidative stress remain unclear.
Makoto Ohara   +9 more
wiley   +1 more source

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

open access: yesJournal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura   +6 more
wiley   +1 more source

SGLT2i use and fracture risk compared with DPP4i in patients with T2DM

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Introduction The association between sodium‐glucose cotransporter‐2 inhibitor (SGLT2i) use and fracture risk remains inconclusive. Most previous studies have focused on treatment‐naïve patients, despite many patients in routine clinical practice initiating SGLT2i therapy after prior dipeptidyl peptidase‐4 inhibitor (DPP4i) use.
Sung‐Yen Lin   +5 more
wiley   +1 more source

The Generics Revolution and the New Economic Geography of the Global Pesticide Industry

open access: yesJournal of Agrarian Change, EarlyView.
ABSTRACT The global pesticide industry transformed from one dominated by patented products and legacy multinationals with strong manufacturing bases in the United States and EU to one dominated by generic products produced in India and China. We use proprietary market research data, data from regulatory filings, industry press and bilateral trade data ...
Christian Berndt   +4 more
wiley   +1 more source

The Capital–Labour–State Dynamics of Herbicide Adoption in Rainfed India

open access: yesJournal of Agrarian Change, EarlyView.
ABSTRACT This paper engages debates around the capital–labour–state dynamics of agrarian transitions to address the oft‐studied but still little‐understood question of why farmers adopt herbicides when they do. Over the last several years, smallholder farmers in India have begun using the herbicide bispyribac sodium at breakneck speeds, particularly in
Carly Nichols, Nidhi Kumari
wiley   +1 more source

Sulfonylurea herbicides

open access: yes, 1991
Available from British Library Document Supply Centre- DSC:q91/15871(Sulfonylurea) / BLDSC - British Library Document Supply CentreSIGLEGBUnited ...
Smith, C   +1 more
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