Results 251 to 260 of about 2,674,072 (303)

Pharmacological treatment patterns, factors associated with glycemic control, and renal function parameters in a real-world cohort of Hispanic adults with type 2 diabetes. [PDF]

open access: yesBiomed Rep
Diaz-Martinez J   +14 more
europepmc   +1 more source

Epac2: a sulfonylurea receptor?

Biochemical Society Transactions, 2012
Sulfonylureas are widely used oral drugs in the treatment of diabetes mellitus. They function by the inhibition of ATP-sensitive K+ channels in pancreatic β-cells, which are thus considered the ‘classical’ sulfonylurea receptor. Next to the ATP-sensitive K+ channels, additional sulfonylurea-interacting proteins were identified, which might contribute ...
H. Rehmann
openaire   +3 more sources

Modification of the Mitochondrial Sulfonylurea Receptor by Thiol Reagents

Biochemical and Biophysical Research Communications, 1999
The purpose of this study was to investigate the effects exerted by thiol-modifying reagents on themitochondrial sulfonylurea receptor. The thiol-oxidizing agents (timerosal and 5, 5'-dithio-bis(2-nitrobenzoic acid)) were found to produce a large inhibition (70% to 80%) of specific binding of [(3)H]glibenclamide to the beef heart mitochondrial membrane.
Adam Szewczyk, Maciej J Nalecz
exaly   +3 more sources

The sulfonylurea receptor Sur is dispensable for chitin synthesis in Drosophila melanogaster embryos.

open access: yesPest Management Science, 2013
Background: Chitin produced by membrane-inserted chitin synthases is an important constituent of the arthropod cuticle and midgut peritrophic matrix. Chitin synthesis inhibitors are common insecticides in pest control.
Frauke Meyer   +2 more
semanticscholar   +2 more sources

Differential interaction of glimepiride and glibenclamide with the β-cell sulfonylurea receptor I. Binding characteristics [PDF]

open access: yesBiochimica Et Biophysica Acta - Biomembranes, 1994
Glimepiride is a novel sulfonylurea drug for treatment of non-insulin-dependent diabetes mellitus with higher blood sugar lowering efficacy in diabetic patients than glibenclamide raising the question whether this characteristics is in line with ...
Gunter Müller, Werner Kramer
exaly   +2 more sources

Sulfonylurea receptor 1-expressing cancer cells induce cancer-associated fibroblasts to promote non-small cell lung cancer progression.

Cancer Letters, 2022
Cancer-associated fibroblasts (CAFs) play a pivotal role in cancer progression; however, how CAFs are induced remains elusive. Sulfonylurea receptor 1 (SUR1) is a tumor-enhancer in non-small cell lung carcinoma (NSCLC).
Hongling Chen   +12 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy