Results 181 to 190 of about 5,907 (256)

Diabetic foot ulcer‐related amputation is associated with twofold increased risk of cardiovascular disease: A Korean National Health Information Database Study

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 1024-1033, June 2026.
Data/Design: Nationwide, population‐based longitudinal cohort using the Korean National Health Insurance Service health checkup database (index 2009–2012) with follow‐up through December 31, 2018. Population/Exposure: Adults with diabetes (N = 1,229,689); DFU‐related amputation at baseline (n = 1,486) vs no DFU‐related amputation.
Jinsun Jang, Bong‐Seong Kim, Hye Won Yang, Heejun Son, Dong Yeon Lee, Min Gyu Kyung, Hwan Jun Jae, Saebeom Hur, Sang Wha Kim, Sanghyun Ahn, Kyung‐Do Han, Soo Heon Kwak   +11 more
wiley   +1 more source

Unraveling Diabetes Mellitus-Driven Tumorigenesis: From Pathophysiological Mechanisms, Therapeutic Drugs to Tailor-Made Nanosystems. [PDF]

Int J Nanomedicine
Jiang Z, Zhou Y, Ma M, Huang M, Wang X.
europepmc   +1 more source

The beta-cell sulfonylurea receptor.

Advances in experimental medicine and biology, 1993
Ashcroft, S, Niki, I, Kenna, S, Weng, L, Skeer, J, Coles, B, Ashcroft, F   +6 more
openaire   +2 more sources

ChREBP drives β‐cell proliferation under metabolic stress but not in pregnancy‐induced β‐cell expansion

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 938-950, June 2026.
ChREBP is a context‐dependent regulator of adaptive β‐cell proliferation. It plays a pivotal role in driving β‐cell expansion under pathophysiological metabolic stress, such as insulin resistance and hyperglycemia, but has a limited role during physiological expansion in pregnancy.
Sodai Kubota, Seiya Banno, Katsumi Iizuka, Hiromi Tsuchida, Saki Kubota‐Okamoto, Teruaki Sakurai, Yoshihiro Takahashi, Toshinori Imaizumi, Takehiro Kato, Yukio Horikawa, Shin Tsunekawa, Ryota Usui, Hisato Tatsuoka, Shinsuke Tokumoto, Takaaki Murakami, Yuuka Fujiwara, Hitoshi Kuwata, Yuji Yamazaki, Yuichiro Yamada, Yutaka Seino, Daisuke Yabe   +20 more
wiley   +1 more source

Pharmaceutical agents targeting K_ATP channel modulate sweet taste sensitivity in mice. [PDF]

J Physiol Sci
Sawai C, Wang K, Horie K, Mitoh Y, Ueda H, Kamioka H, Yoshida R.   +6 more
europepmc   +1 more source

Five‐year follow‐up of incretin‐based therapy in a patient with KCNJ11‐related permanent neonatal diabetes: Achieving insulin discontinuation and sulfonylurea reduction

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 1075-1078, June 2026.
In a woman with KCNJ11‐related permanent neonatal diabetes mellitus, incretin‐based therapy enabled insulin discontinuation and maintained glycemic control for more than 5 years, with HbA1c between 6.1% and 6.5% on the lowest semaglutide dose, dose‐dependent improvement in insulin secretion, and an approximately 60% reduction in glibenclamide dose ...
Toshiaki Ohkuma, Ryoichiro Aotani, Wakako Sakamoto, Ayaka Oshiro, Tetsuro Ago   +4 more
wiley   +1 more source

ArcDFI: Attention regularization guided by CYP450 interactions for predicting drug-food interactions. [PDF]

PLoS Comput Biol
Gim M, Kang J, Park D, Jeon M.
europepmc   +1 more source

Impact of COVID‐19 restrictions and their relaxation on body composition and glycemic control in individuals with glucose intolerance in Japan: A single‐center observational study

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 1063-1074, June 2026.
This study examined glycemic control, body composition, and lifestyle changes in 221 outpatients with glucose intolerance (GI) in Japan across the pre‐state of emergency (SOE), SOE, and post‐SOE periods. HbA1c increased despite body weight reduction, with progressive muscle loss.
Ami Kobayashi, Yamato Keidai, Takaaki Murakami, Ryo Tsukaguchi, Miharu Fujita, Keiko Wada, Daisuke Yabe   +6 more
wiley   +1 more source

Understanding the structural basis of ALS mutations associated with resistance to sulfonylurea in wheat. [PDF]

Sci Rep
Kumar P, Bishnoi R, Priyadarshini P, Chhuneja P, Singla D.   +4 more
europepmc   +1 more source

A Remote Chronic Disease Management Program to Improve Cardiovascular and Metabolic Outcomes in a Diverse Community‐Based Diabetic Population: Study Design of the TAMIS Trial

Journal of Evaluation in Clinical Practice, Volume 32, Issue 4, June 2026.
ABSTRACT Introduction Cardiovascular and cerebrovascular diseases are projected to expand in the coming decades as the main cause of death. This study outlines the escalating burden of cardiovascular diseases in low‐ and middle‐income countries (LMICs), particularly in Latin America (LA), which is expected to surpass that of other high‐population ...
Renato de Carvalho Barros, Andrea Stephanus, José Antonio Barbosa Filho, Evellyn Mariana, Yasmim Botelho, Thaiene M. M. Severino, Robson Conceição Silva, Lucila de Jesus Almeida, Cristiane Koeche, Bruno Gedeon, Mariana Guimarães Souza de Oliveira, Ana Carolina Augusto, Catarina Ferraz, F. Enzo, Gabriela de Lima, Julia Andrade Ibiapina, Giselle Pinto, Sérgio Henrique Rodolpho Ramalho, Ana Claudia C. Nogueira, Andrei C. Sposito, Alessandra M. Campos‐Staffico, Alexandre Anderson S. M. Soares, Luiz Sérgio F. de Carvalho   +22 more
wiley   +1 more source