Results 231 to 240 of about 5,907 (256)

The KATP Channel and the Sulfonylurea Receptor

2001
ATP-sensitive K+ channels (KAgp channels) were first described in cardiac myocytes (1) and were subsequently found in many other tissues including pancreatic 13-cells (25), skeletal muscle (6), smooth muscle (7), brain (8), pituitary (9), and kidney (10) and in mitochondria (11).
Susumu Seino, Takashi Miki, Hideki Yano
openaire   +1 more source

Role of the sulfonylurea receptor in regulating human adipocyte metabolism

The FASEB Journal, 1999
ABSTRACT A regulatory role for intracellular Ca 2+ ([Ca 2+ ] i ) in adipocyte lipogenesis, lipolysis and triglyceride accumulation has been demonstrated.
H, Shi, N, Moustaid-Moussa, W O, Wilkison, M B, Zemel   +3 more
openaire   +2 more sources

Sulfonylurea receptor–associated channels

Neurology, 2017
The sulfonylurea receptors (SURs) 1 (SUR1) and 2 (SUR2) are members of the adenosine triphosphate (ATP) binding cassette transporters superfamily. Unlike other members of this superfamily, these receptors are not involved in transport but associate with pore-forming subunits to form cation channels.
openaire   +2 more sources

Control of insulin secretion by sulfonylureas, meglitinide and diazoxide in relation to their binding to the sulfonylurea receptor in pancreatic islets

Biochemical Pharmacology, 1989
Sulfonylureas inhibit an ATP-dependent K+ channel in the B-cell plasma membrane and thereby initiate insulin release. Diazoxide opens this channel and inhibits insulin release. In mouse pancreatic islets, we have explored whether other targets for these drugs must be postulated to explain their hypo- or hyperglycaemic properties. At non-saturating drug
U, Panten, J, Burgfeld, F, Goerke, M, Rennicke, M, Schwanstecher, A, Wallasch, B J, Zünkler, S, Lenzen   +7 more
openaire   +2 more sources

Radiolabeling and brain penetration of [11C]VU0071063, a ligand of type 1 sulfonylurea receptors for positron emission tomography imaging

Journal of Labelled Compounds and Radiopharmaceuticals, 2022
Fabien Caille, Wadad Saba, Sébastien Goutal   +2 more
exaly  

Sulfonylurea Receptor

2006
openaire   +2 more sources

Sulfonylurea receptors and mechanism of sulfonylurea action

Experimental and Clinical Endocrinology and Diabetes, 1996
U Panten, Christina Schwanstecher
exaly  

The ß-Cell Sulfonylurea Receptor

1993
Stephen J. H. Ashcroft, Ichiro Niki, Sue Kenna, Ling Weng, Jackie Skeer, Barbara Coles, Frances M. Ashcroft   +6 more
openaire   +1 more source

Dual actions of sulfonylureas and glyburide. Receptor and post-receptor effects.

The American journal of medicine, 1985
Glyburide and other sulfonylureas consistently enhance receptor binding in cells from patients with non-insulin-dependent diabetes mellitus, whereas no effects and mixed effects have been demonstrated in cells from patients with insulin-dependent diabetes mellitus and in normal cells, respectively.
openaire   +1 more source

[Sulfonylurea receptor].

Nihon rinsho. Japanese journal of clinical medicine, 1997
Y, Yamada, Y, Seino
openaire   +1 more source