Results 71 to 80 of about 31,215 (290)

A cardiologic approach to non-insulin antidiabetic pharmacotherapy in patients with heart disease [PDF]

, 2009
Classical non-insulin antihyperglycemic drugs currently approved for the treatment of type 2 diabetes mellitus (T2DM) comprise five groups: biguanides, sulfonylureas, meglitinides, glitazones and alpha-glucosidase inhibitors.
Enrique Z Fisman, Alexander Tenenbaum
core   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

Monogenic Diabetes: Genetic Insight and Precision Therapeutics in the Management of MODY

Exon
A monogenic diabetes, specifically, the Maturity-onset diabetes of the young (MODY) is the consequence of the single-gene mutations that are responsible for transcription factors such as HNF1A and GCK taking effect on the insulin synthesis, glucose ...
Gayathri Venkatesan, Kala vetha Kumari, Ariya S S, Princy Vijayababu   +3 more
doaj   +1 more source

New weed control strategies in maize considering narrow crop rotations with maize, greater ALSresistance in common weeds and application restrictions with regard to active substance

Julius-Kühn-Archiv, 2014
Many herbicides with different HRAC-groups are available for weed control in maize. Because of narrow maize crop rotation summer weeds and warmth loving weeds are encouraged.
Ewert, Katrin, Schröder, Gerhard, Meinlschmidt, Ewa, Bergmann, Elke   +3 more
doaj   +1 more source

How beneficial are thiazolidinediones for diabetes mellitus? [PDF]

, 2002
The thiazolidinediones pioglitazone (Actos) and rosiglitazone (Avandia) are effective at lowering fasting plasma glucose (FPG) and glycosylated hemoglobin (Hb A1c) in patients with type 2 diabetes when used either as monotherapy or in combination with ...
Culhane, Nicole S., Graves, Rebecca S.
core  

Safety and Efficacy of Glucagon‐Like Peptide‐1 Receptor Agonists Use in Elderly People With Obesity—A Meta‐Analysis

Obesity, EarlyView.
ABSTRACT Objective This meta‐analysis evaluates the safety and efficacy of glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) for the treatment of older adults with obesity compared to younger individuals. Methods A systematic review was conducted following PRISMA guidelines (PROSPERO CRD420251074381).
Inês Rego de Figueiredo, Filipa Sofia Simas, Angela Ghiletchi, João Oliveira Torres, José Silva‐Nunes   +4 more
wiley   +1 more source

Role of oral hypoglycemic agents in the management of type 2 diabetes mellitus during Ramadan

Indian Journal of Endocrinology and Metabolism, 2012
It is obligatory for all adult Muslims to observe fast during the holy month of Ramadan, but sick individuals including those with diabetes mellitus are exempted from the duty of fasting.
Mir Iftikhar Bashir, Md Faruque Pathan, Syed Abbas Raza, Jamal Ahmad, A K Azad Khan, Osama Ishtiaq, Rakesh K Sahay, Aisha Sheikh, Abdul Hamid Zargar   +8 more
doaj   +1 more source

Preventing Unnecessary Costs of Drug-Induced Hypoglycemia in Older Adults with Type 2 Diabetes in the United States and Canada. [PDF]

PLoS ONE, 2016
BACKGROUND:The costs of drug-induced hypoglycemia are a critical but often neglected component of value-based arguments to reduce tight glycemic control in older adults with type 2 diabetes.
Mathieu Boulin, Vakaramoko Diaby, Cara Tannenbaum   +2 more
doaj   +1 more source

Pharmacogenetics of oral antidiabetic drugs [PDF]

, 2013
Oral antidiabetic drugs (OADs) are used for more than a half-century in the treatment of type 2 diabetes. Only in the last five years, intensive research has been conducted in the pharmacogenetics of these drugs based mainly on the retrospective register
Becker, Matthijs L., Pearson, Ewan R., Tkáč, Ivan   +2 more
core   +5 more sources

Sulfonylurea action re‐revisited [PDF]

Journal of Diabetes Investigation, 2010
Sulfonylureas (SU), commonly used in the treatment of type 2 diabetes mellitus (T2DM), stimulate insulin secretion by inhibiting adenosine triphosphate (ATP)‐sensitive K+ (KATP) channels in pancreatic β‐cells. SU are now known to also activate cyclic adenosine monophosphate (cAMP) sensor Epac2 (cAMP‐GEFII) to Rap1 signaling, which promotes insulin ...
Seino, Susumu, Chang-Liang Zhang, Shibasaki, Tadao   +2 more
openaire   +2 more sources