Results 11 to 20 of about 29,600 (252)

Broccoli for the brain: a review of the neuroprotective mechanisms of sulforaphane [PDF]

Frontiers in Cellular Neuroscience
Sulforaphane, a phytochemical abundant in the sprouts of cruciferous vegetables, protects plants during a critical period of development. Through sulforaphane’s ability to activate the mammalian Nuclear Factor Erythroid 2-related Factor 2 (NRF2) pathway,
Riley N. Bessetti, Riley N. Bessetti, Karen A. Litwa, Karen A. Litwa   +3 more
doaj   +3 more sources

Anticancer properties of sulforaphane: current insights at the molecular level

Frontiers in Oncology, 2023
Sulforaphane (SFN) is an isothiocyanate with multiple biomedical applications. Sulforaphane can be extracted from the plants of the genus Brassica. However, broccoli sprouts are the chief source of sulforaphane and are 20 to 50 times richer than mature ...
Muhammad Asif Ali, Noohela Khan, Nabeeha Kaleem, Waqas Ahmad, Salem Hussain Alharethi, Bandar Alharbi, Hassan H. Alhassan, Maher M. Al-Enazi, Ahmad Faizal Abdull Razis, Ahmad Faizal Abdull Razis, Babagana Modu, Babagana Modu, Daniela Calina, Javad Sharifi-Rad   +13 more
doaj   +2 more sources

Sulforaphane-driven reprogramming of gut microbiome and metabolome ameliorates the progression of hyperuricemia

Journal of Advanced Research, 2023
Introduction: Currently, revealing how to prevent and control hyperuricemia has become an essential public health issue. Sulforaphane has a wide range of applications in the management of hyperuricemia.
Ruoyu Wang, Mairepaiti Halimulati, Xiaojie Huang, Yuxin Ma, Lutong Li, Zhaofeng Zhang   +5 more
doaj   +2 more sources

Broccoli or Sulforaphane:Is It the Source or Dose That Matters? [PDF]

Molecules, 2019
There is robust epidemiological evidence for the beneficial effects of broccoli consumption on health, many of them clearly mediated by the isothiocyanate sulforaphane.
Albena T. Dinkova-Kostova, Chen, Egner, Fahey, Fahey, Fahey, Graham, Jed W. Fahey, Kombairaju, Myzak, Shapiro, Shapiro, Sreerama, Thomas W. Kensler, Yoko Yagishita   +14 more
core   +3 more sources

Sulforaphane: a natural organosulfur having potential to modulate apoptosis and survival signalling in cancer [PDF]

Discover Oncology
Owing to its ever-growing range of pharmacological advantages, sulforaphane, an isothiocyanate from cruciferous vegetables such as broccoli, is becoming increasingly popular.
Hemant Joshi, Isha Rani, Vikas Sharma, Ujjawal Sharma, Tanisha Dimri, Manoj Kumar, Ritu Chauhan, Abhishek Chauhan, Damandeep Kaur, Shafiul Haque, Faraz Ahmad, Hardeep Singh Tuli   +11 more
doaj   +2 more sources

Investigating Sulforaphane’s anti-virulence and anti-quorum sensing properties against Pseudomonas aeruginosa

Frontiers in Pharmacology
BackgroundP. aeruginosa, a significant bacterium, can cause severe illness and resistance to antibiotics. Quorum sensing (QS) systems regulate virulence factors production.
Mahmoud M. Bendary, Mohamed A. M. Ali, Mohamed A. M. Ali, Alyaa S. Abdel Halim, Fehmi Boufahja, Anis Ahmad Chaudhary, Amr Elkelish, Amr Elkelish, Rania H. M. Soliman, Wael A. H. Hegazy, Wael A. H. Hegazy   +10 more
doaj   +2 more sources

Sulforaphane reduces obesity by reversing leptin resistance

eLife, 2022
The ascending prevalence of obesity in recent decades is commonly associated with soaring morbidity and mortality rates, resulting in increased health-care costs and decreased quality of life.
Işın Çakır, Pauline Lining Pan, Colleen K Hadley, Abdulrahman El-Gamal, Amina Fadel, Dina Elsayegh, Omnia Mohamed, Nasser M Rizk, Masoud Ghamari-Langroudi   +8 more
doaj   +2 more sources

Therapeutic effects of sulforaphane in ulcerative colitis: effect on antioxidant activity, mitochondrial biogenesis and DNA polymerization

Redox Report, 2022
Objectives Ulcerative colitis (UC), an inflammatory bowel disease, affects mucosal lining of colon leading to inflammation and ulcers. Sulforaphane is a natural compound obtained from cruciferous vegetables.
Abdullah Alattar, Reem Alshaman, Mohammed M. H. Al-Gayyar   +2 more
doaj   +2 more sources

Sulforaphane Ameliorates the Severity of Psoriasis and SLE by Modulating Effector Cells and Reducing Oxidative Stress

Frontiers in Pharmacology, 2022
Background: Sulforaphane, which is found in cruciferous vegetables, has been reported to have anti-inflammatory, antioxidant, and antitumour activities.
Pei Du, Pei Du, Pei Du, Pei Du, Wenqian Zhang, Wenqian Zhang, Wenqian Zhang, Wenqian Zhang, Haobo Cui, Wei He, Shuang Lu, Shuang Lu, Shuang Lu, Shuang Lu, Sujie Jia, Sujie Jia, Ming Zhao, Ming Zhao, Ming Zhao, Ming Zhao   +19 more
doaj   +2 more sources

Sulforaphane prevents age‐associated cardiac and muscular dysfunction through Nrf2 signaling [PDF]

Aging Cell, 2020
Age‐associated mitochondrial dysfunction and oxidative damage are primary causes for multiple health problems including sarcopenia and cardiovascular disease (CVD).
C. Bose, Inês N Alves, Preeti Singh, P. Palade, E. Carvalho, E. Børsheim, Se-Ran Jun, A. Cheema, M. Boerma, S. Awasthi, Sharda P. Singh   +10 more
semanticscholar   +2 more sources