Results 21 to 30 of about 14,451 (212)

Efficacy of Sulforaphane in Neurodegenerative Diseases [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Sulforaphane (SFN) is a phytocompound belonging to the isothiocyanate family. Although it was also found in seeds and mature plants, SFN is mainly present in sprouts of many cruciferous vegetables, including cabbage, broccoli, cauliflower, and Brussels sprouts.
Schepici, Giovanni   +2 more
openaire   +2 more sources

Factors Influencing Glucoraphanin and Sulforaphane Formation in Brassica Plants: A Review

open access: yesJournal of Integrative Agriculture, 2012
Sulforaphane is a type of sulfur-containing isothiocyanates hydrolyzed from glucosinolates by myrosinase found in Brassica plants. Sulforaphane is a naturally occurring inducer of phase II enzymes in human and animal bodies to detoxify cancer-causing ...
Zhen-xin GU, Qiang-hui GUO, Ying-juan GU
doaj   +1 more source

Sulforaphane-driven reprogramming of gut microbiome and metabolome ameliorates the progression of hyperuricemia

open access: yesJournal of Advanced Research, 2023
Introduction: Currently, revealing how to prevent and control hyperuricemia has become an essential public health issue. Sulforaphane has a wide range of applications in the management of hyperuricemia.
Ruoyu Wang   +5 more
doaj   +1 more source

Research Progress on Sulforaphane in the Prevention and Treatment of Nervous System Diseases [PDF]

open access: yesShipin Kexue, 2023
Sulforaphane is a natural product with excellent antioxidant and anti-inflammatory effects, which is ubiquitous in plants of the Brassicaceae family. The pathogenesis of nervous system diseases is complex, but many nervous system diseases are related to ...
SONG Xiaoye, PANG Xinyi, LU Yingjian
doaj   +1 more source

Effect of Storage Conditions and Cooking Methods on Chlorophyll, Glucosinolate, and Sulforaphane Content in Broccoli Florets

open access: yesHorticulturae, 2021
The effects of storage conditions and cooking methods on chlorophyll, glucosinolate (GSL), and sulforaphane content in broccoli florets were investigated in this study.
Junwei Wang   +8 more
doaj   +1 more source

Chemopreventive activity of sulforaphane

open access: yesDrug Design, Development and Therapy, 2018
Cancer is one of the major causes of morbidity and mortality in the world. Carcinogenesis is a multistep process induced by genetic and epigenetic changes that disrupt pathways controlling cell proliferation, apoptosis, differentiation, and senescence.
Xin Jiang   +6 more
openaire   +5 more sources

Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator sulforaphane. [PDF]

open access: yesPLoS ONE, 2012
Sulforaphane-induced activation of the transcription factor NF-E2 related factor 2 (Nrf2 or the gene Nfe2l2) and subsequent induction of the phase II antioxidant system has previously been shown to exert neuroprotective action in a transient model of ...
Michelle J Porritt   +6 more
doaj   +1 more source

Sulforaphane Targets TRA-1/GLI Upstream of DAF-16/FOXO to Promote C. elegans Longevity and Healthspan

open access: yesFrontiers in Cell and Developmental Biology, 2021
Broccoli-derived isothiocyanate sulforaphane inhibits inflammation and cancer. Sulforaphane may support healthy aging, but the underlying detailed mechanisms are unclear. We used the C. elegans nematode model to address this question.
Huihui Ji   +9 more
doaj   +1 more source

Sulforaphane targets cancer stemness and tumor initiating properties in oral squamous cell carcinomas via miR-200c induction

open access: yesJournal of the Formosan Medical Association, 2017
Background/Purpose: Cancer stem cells (CSCs) are deemed as the driving force of tumorigenesis in oral squamous cell carcinomas (OSCCs). In this study, we investigated the chemotherapeutic effect of sulforaphane, a dietary component from broccoli sprouts,
Chia-Ming Liu   +7 more
doaj   +1 more source

The anti-arthritis effect of sulforaphane, an activator of Nrf2, is associated with inhibition of both B cell differentiation and the production of inflammatory cytokines.

open access: yesPLoS ONE, 2021
Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) is an important transcription factor that plays a pivotal role in cellular defense against oxidative injury.
Su-Jin Moon   +7 more
doaj   +1 more source

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