Antileukemic activity of sulforaphane in primary blasts from patients affected by myelo- and lympho-proliferative disorders and in hypoxic conditions. [PDF]
Sulforaphane is a dietary isothiocyanate found in cruciferous vegetables showing antileukemic activity. With the purpose of extending the potential clinical impact of sulforaphane in the oncological field, we investigated the antileukemic effect of ...
Carmela Fimognari +8 more
doaj +1 more source
Stimulation of phagocytosis by sulforaphane [PDF]
Sulforaphane, a major isothiocyanate derived from cruciferous vegetables, protects living systems against electrophile toxicity, oxidative stress, inflammation, and radiation. A major protective mechanism is the induction of a network of endogenous cytoprotective (phase 2) genes that are regulated by transcription factor Nrf2. To obtain a more detailed
Hiroyuki, Suganuma +4 more
openaire +2 more sources
Efficacy of Sulforaphane in Neurodegenerative Diseases [PDF]
Sulforaphane (SFN) is a phytocompound belonging to the isothiocyanate family. Although it was also found in seeds and mature plants, SFN is mainly present in sprouts of many cruciferous vegetables, including cabbage, broccoli, cauliflower, and Brussels sprouts.
Schepici, Giovanni +2 more
openaire +2 more sources
Factors Influencing Glucoraphanin and Sulforaphane Formation in Brassica Plants: A Review
Sulforaphane is a type of sulfur-containing isothiocyanates hydrolyzed from glucosinolates by myrosinase found in Brassica plants. Sulforaphane is a naturally occurring inducer of phase II enzymes in human and animal bodies to detoxify cancer-causing ...
Zhen-xin GU, Qiang-hui GUO, Ying-juan GU
doaj +1 more source
Characterization of theThreshold for NAD(P)H:quinone Oxidoreductase Activity in Intact Sulforaphane-treated Pulmonary Arterial Endothelial Cells [PDF]
Treatment of bovine pulmonary arterial endothelial cells in culture with the phase II enzyme inducer sulforaphane (5 μM, 24 h; sulf-treated) increased cell-lysate NAD(P)H:quinone oxidoreductase (NQO1) activity by 5.7 ± 0.6 (mean ± SEM)-fold, but intact ...
Bongard, Robert D. +5 more
core +2 more sources
Kinetics of sulforaphane in mice after consumption of sulforaphane‐enriched broccoli sprout preparation [PDF]
ScopeSulforaphane (SF) is a natural isothiocyanate in broccoli sprouts with cancer chemopreventive activity. This study is aimed to use different methods to develop broccoli sprout preparations to compare their ability to deliver SF to the mice and to evaluate the kinetics and biodistribution of SF.Methods and resultsThe SF‐enriched sprout preparation ...
Li, Yanyan +5 more
openaire +3 more sources
Introduction: Currently, revealing how to prevent and control hyperuricemia has become an essential public health issue. Sulforaphane has a wide range of applications in the management of hyperuricemia.
Ruoyu Wang +5 more
doaj +1 more source
Research Progress on Sulforaphane in the Prevention and Treatment of Nervous System Diseases [PDF]
Sulforaphane is a natural product with excellent antioxidant and anti-inflammatory effects, which is ubiquitous in plants of the Brassicaceae family. The pathogenesis of nervous system diseases is complex, but many nervous system diseases are related to ...
SONG Xiaoye, PANG Xinyi, LU Yingjian
doaj +1 more source
Effect of stevia supplementation of kale juice spheres on their quality changes during refrigerated shelf life [PDF]
Kale is a vegetable with high contents of health–promoting compounds although its consumption as a beverage is highly limited due to its bitter flavour. Nonetheless, the bitter flavour of Brassicas may be masked by sweetening.
Artés Calero, Francisco +4 more
core +2 more sources
The effects of storage conditions and cooking methods on chlorophyll, glucosinolate (GSL), and sulforaphane content in broccoli florets were investigated in this study.
Junwei Wang +8 more
doaj +1 more source

