Results 11 to 20 of about 7,639 (223)
The important roles of steroid sulfatase and sulfotransferases in gynecological diseases [PDF]
Frontiers in Pharmacology, 2016 Gynecological diseases such as endometriosis, adenomyosis and uterine fibroids, and gynecological cancers including endometrial cancer and ovarian cancer, affect a large proportion of women.
Tea eLanisnik Rizner
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Sulfotransferases and Sulfatases in Mycobacteria [PDF]
Chemistry & Biology, 2002 Analysis of the genomes of M. tuberculosis, M. leprae, M. smegmatis, and M. avium has revealed a large family of genes homologous to known sulfotransferases. Despite reports detailing a suite of sulfated glycolipids in many mycobacteria, a corresponding family of sulfotransferase genes remains uncharacterized.
Mougous, Joseph D +4 more
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JCI InsightSjögren’s disease is a chronic autoimmune disease characterized by symptoms of oral and ocular dryness and extraglandular manifestations. Mouth dryness is not only due to reduced saliva volume, but also to alterations in the quality of salivary mucins in
Matilde Nuñez +14 more
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Induction of PNAd and N-acetylglucosamine 6-O-sulfotransferases 1 and 2 in mouse collagen-induced arthritis [PDF]
BMC Immunology, 2006 Background Leukocyte recruitment across blood vessels is fundamental to immune surveillance and inflammation. Lymphocyte homing to peripheral lymph nodes is mediated by the adhesion molecule, L-selectin, which binds to sulfated carbohydrate ligands on ...
Rosen Steven D +3 more
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Frontiers in Bioengineering and Biotechnology, 2023 Sulfation of molecules in living organisms is a process that plays a key role in their functionality. In mammals, the sulfation of polysaccharides (glycosaminoglycans) that form the proteoglycans present in the extracellular matrix is particularly ...
Dianelis T. Monterrey +3 more
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Steroid sulfotransferases [PDF]
Journal of Endocrinology, 1996 Abstract Human dehydroepiandrosterone sulfotransferase (DHEA-ST) catalyzes the sulfonation of DHEA, cholesterol, pregnenolone as well as androsterone. RNA blot analysis shows two DHEA-ST mRNA species of 1·3 and 1·8 kb that are expressed similarly in liver and adrenals. To determine whether the form expressed in adrenals is distinct or
V, Luu-The, F, Bernier, I, Dufort
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The Role of Sulfation in Nematode Development and Phenotypic Plasticity
Frontiers in Molecular Biosciences, 2022 Sulfation is poorly understood in most invertebrates and a potential role of sulfation in the regulation of developmental and physiological processes of these organisms remains unclear. Also, animal model system approaches did not identify many sulfation-
Catia Igreja, Ralf J. Sommer
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Carbohydrate sulfotransferases [PDF]
, 2023 Carbohydrate sulfotransferases (CHST) catalyse the biosynthesis of proteoglycans that enable physical interactions and signalling between different neighbouring cells in physiological and pathological states.
Gramos Begolli +7 more
core +1 more source
Inhibition of Human Sulfotransferases by Phthalate Monoesters
Frontiers in Endocrinology, 2022 ObjectiveThis study aimed to investigate the inhibition of human important phase II metabolic enzyme sulfotransferases (SULTs) by phthalate monoesters, which are important metabolites of phthalate esters (PAEs).MethodRecombinant SULT-catalyzed metabolism
Hui Huang +10 more
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Hepatology, EarlyView., 2022 CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli +13 more
wiley +1 more source