Results 1 to 10 of about 13,601 (188)
The effect of weight, body mass index, age, sex , and race on plasma concentrations of subcutaneous sumatriptan: a pooled analysis [PDF]
Clinical Pharmacology: Advances and Applications, 2016 Sagar Munjal,1 Anirudh Gautam,2 Alan M Rapoport,3 Dennis M Fisher4 1Department of Neurology Clinical Development and Medical Affairs, Dr. Reddy’s Laboratories Ltd, Princeton, NJ, USA; 2Pharmacokinetics, Modeling and Simulation & ...
Munjal S +3 more
doaj +5 more sources
Pharmacological challenge with a serotonin 1D agonist in alcohol dependence [PDF]
BMC Psychiatry, 2005 Background Both animal and clinical studies have implicated serotonergic dysfunction in the pathogenesis of alcohol abuse and dependence. However the exact mechanisms involved remain unknown. Theoretically, low serotonin promotes alcohol seeking behavior.
Pienaar Willie +4 more
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Sumatriptan Induced Brugada Syndrome, a Rare Presentation of a Commonly Used Drug [PDF]
Clinical Case ReportsWe aim to highlight an important and rare association of Brugada Syndrome with a commonly used medication, Sumatriptan, which is used as an aborting Migraine headaches.
Phool Iqbal +7 more
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Dihydroergotamine, ergotamine, methysergide and sumatriptan - Basic science in relation to migraine treatment [PDF]
, 2012 The 5-hydroxytryptamine (5-HT) receptor family mediates the effects of several drugs highly effective in migraine primarily by activating 5-HT 1B, 5-HT1D, and 5-HT1F receptors.
Dahlöf, C. (Carl) +1 more
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The Use of Neuroimaging for Predicting Sumatriptan Treatment Response in Patients With Migraine
Frontiers in Neurology, 2022 ObjectivesTo identify the neuroimaging predictors for the responsiveness of patients to sumatriptan and use an independent cohort for external validation.MethodsStructuralized headache questionnaire and 3-Tesla brain magnetic resonance imaging were ...
Jr-Wei Wu +19 more
doaj +1 more source
Cephalalgia Reports, 2021 Objective: This randomized, partially-blinded, placebo-controlled study evaluated hemodynamic effects, pharmacokinetic interactions, and safety of concomitant administration of oral rimegepant and subcutaneous sumatriptan.
Robert Croop +9 more
doaj +1 more source
Metabolism of sumatriptan revisited
Pharmacology Research & Perspectives, 2023 Scientific literature describes that sumatriptan is metabolized by oxidative deamination of its dimethylaminoethyl residue by monoamine oxidase A (MAO A) and not by cytochrome P450 (CYP)‐mediated demethylation, as is usual for such structural elements ...
Timo Pöstges, Matthias Lehr
doaj +1 more source
Archives of Academic Emergency Medicine, 2022 Introduction: Migraine headaches can cause severe pain for patients and lead them to multiple visits to the emergency department (ED). This study aimed to evaluate the efficacy of propofol + sumatriptan combination in comparison with sumatriptan alone ...
Reza Farahmand Rad +3 more
doaj +1 more source
Protective Roles of N-acetyl Cysteine and/or Taurine against Sumatriptan-Induced Hepatotoxicity [PDF]
Advanced Pharmaceutical Bulletin, 2016 Purpose: Triptans are the drug category mostly prescribed for abortive treatment of migraine. Most recent cases of liver toxicity induced by triptans have been described, but the mechanisms of liver toxicity of these medications have not been clear ...
Javad Khalili Fard +3 more
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