Results 11 to 20 of about 291,935 (374)
SUMO targeting of a stress-tolerant Ulp1 SUMO protease. [PDF]
PLoS ONE, 2018 SUMO proteases of the SENP/Ulp family are master regulators of both sumoylation and desumoylation and regulate SUMO homeostasis in eukaryotic cells. SUMO conjugates rapidly increase in response to cellular stress, including nutrient starvation, hypoxia ...
Jennifer Peek +8 more
doaj +5 more sources
Identification of proximal SUMO-dependent interactors using SUMO-ID [PDF]
Nature Communications, 2020 The fast dynamics and reversibility of posttranslational modifications by the ubiquitin family pose significant challenges for research. Here we present SUMO-ID, a technology that merges proximity biotinylation by TurboID and protein-fragment ...
Orhi Barroso-Gomila +15 more
semanticscholar +8 more sources
SUMO: a history of modification. [PDF]
Molecular Cell, 2005 The small ubiquitin-like modifier (SUMO) is covalently linked to a variety of proteins and is deconjugated by SUMO-specific proteases. A characteristic of SUMO modification is that the biological consequences of conjugation do not appear proportionate to the small fraction of substrate that is modified.
R. Hay
semanticscholar +4 more sources
EMBO Journal, 2021 DNA‐protein crosslinks (DPCs) obstruct essential DNA transactions, posing a serious threat to genome stability and functionality. DPCs are proteolytically processed in a ubiquitin‐ and DNA replication‐dependent manner by SPRTN and the proteasome but can ...
Julio C Y Liu +15 more
semanticscholar +1 more source
Performance Evaluation of DSRC-Zigbee Heterogeneous Network for Intelligent Transportation System
Jurnal Elektronika dan Telekomunikasi, 2021 Transportation is one of the primary needs of human beings that cannot be avoided, with the increasing vehicle can lead to a congested road situation which can lead to less safe road safety.
Randi Eriko Hariyadi +2 more
doaj +1 more source
Therapeutic Potential of Targeting the SUMO Pathway in Cancer
Cancers, 2021 Simple Summary The small ubiquitin-like modifier (SUMO) pathway regulates the hallmark properties of cancer cells. Moreover, alterations in activity and in levels of SUMO machinery components have been observed in human cancer.
Antti Kukkula +5 more
semanticscholar +1 more source
Water Science and Technology, 2022 The development of commercial software and simulators has progressed to assist engineers to optimize design, operation, and control of wastewater treatment processes.
Cheng Yang +2 more
doaj +1 more source
SUMO is a pervasive regulator of meiosis
eLife, 2021 Protein modification by SUMO helps orchestrate the elaborate events of meiosis to faithfully produce haploid gametes. To date, only a handful of meiotic SUMO targets have been identified.
Nikhil R Bhagwat +12 more
semanticscholar +1 more source
Molecules, 2021 One major role of the eukaryotic peptidic post-translational modifier SUMO in the cell is transcriptional control. This occurs via modification of virtually all classes of transcriptional actors, which include transcription factors, transcriptional ...
Mathias Boulanger +4 more
semanticscholar +1 more source
Promyelocytic leukemia nuclear body-like structures can assemble in mouse oocytes
Biology Open, 2022 Promyelocytic leukemia (PML) nuclear bodies (PML-NBs), a class of membrane-less cellular organelles, participate in various biological activities. PML-NBs are known as the core-shell-type nuclear body, harboring ‘client’ proteins in their core.
Osamu Udagawa +2 more
doaj +1 more source