Results 121 to 130 of about 31,613 (261)

New insights into SUMOylation and NEDDylation in fibrosis

Frontiers in Pharmacology
Fibrosis is the outcome of any abnormal tissue repair process that results in normal tissue replacement with scar tissue, leading to persistent tissue damage and cellular injury. During the process of fibrosis, many cytokines and chemokines are involved,
Jin Han, Jin Han, Jun Wu, Wen-Tao Kou, Wen-Tao Kou, Li-Na Xie, Li-Na Xie, Ya-Li Tang, Ya-Li Tang, Da-Long Zhi, Da-Long Zhi, Ping Li, Dan-Qian Chen, Dan-Qian Chen   +13 more
doaj   +1 more source

Regulation of Smad4 Sumoylation and Transforming Growth Factor-β Signaling by Protein Inhibitor of Activated STAT1 [PDF]

, 2004
Min Liang, Frauke Melchior, Xin‐Hua Feng, Xia Lin   +3 more
openalex   +1 more source

OsCK2 Phosphorylates OsSIZ1 to Regulate Phosphate Starvation Response and Defence Response in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Phosphorus is a crucial nutrient for the normal growth and development of rice. Enhancing the efficiency of phosphorus acquisition in plants is vital for optimising soil phosphorus utilisation. The SUMO E3 ligase OsSIZ1 is an important factor for regulating plant phosphorus acquisition and starvation response in rice. However, how its activity
Mengyang Xie, Xiaoli Yang, Wang Chen, Hudong Kuang, Yanhua Zhu, Zhujun Wang, Honghui Lin, Jian Yang   +7 more
wiley   +1 more source

Constitutive nitric oxide synthases deficiency impairs cyclobutane pyrimidine dimer repair following solar UV exposure in cells and mice

Photochemistry and Photobiology, EarlyView.
Proposed model for the dual role of cNOS in DNA damage and repair upon UV radiation. Abstract Solar ultraviolet (sUV) radiation is a major environmental factor that induces DNA damage, promoting skin aging and carcinogenesis. The formation of cyclobutane pyrimidine dimers (CPDs) is one of the most prevalent forms of UV‐induced DNA lesions, playing a ...
Veronica Bahamondes Lorca, Yuxi Zhou, Christina Athans, Hailey Payne, Madison Wright, Zeinab Feyyaz, Lingying Tong, Dawn L. Sammons, Shiyong Wu   +8 more
wiley   +1 more source

Dynamin Interacts with Members of the Sumoylation Machinery [PDF]

, 2004
Ram Kumar Mishra, Shashidhar S. Jatiani, Ashutosh Kumar, Venkateswara R. Simhadri, Ramakrishna V. Hosur, Rohit Mittal   +5 more
openalex   +1 more source

Sex differences in the physiological response to acute anterior cruciate ligament overuse

The Journal of Physiology, EarlyView.
Abstract figure legend With equivalent in vivo fatigue loading of the anterior cruciate ligament (ACL), females accumulate more tissue damage and mount a slower reparative response than males, when the applied loads between sexes are equivalent. By contrast, males accumulate less tissue damage and mount a robust reparative response that includes ...
Stephen H. Schlecht, Benjamin E. Loflin, Adam R. Carter, Roufael Hanna, Simran Shergill, Edward M. Wojtys   +5 more
wiley   +1 more source

Hypoxia and the cytoskeleton

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic outlining the activation of hypoxia‐sensitive pathways, the influence of hypoxia and associated pathways on the cytoskeleton, and the impact of these on disease progression. Abstract A highly‐regulated and dynamic cytoskeleton is vital for functional cellular physiology and the maintenance of homeostasis.
Darragh Flood, Cormac T. Taylor
wiley   +1 more source

Articles selected by Faculty of 1000: proteomics of sumoylation; single-molecule sequencing; membrane glycoproteomics; MHC haplotype sequencing; transcriptome evolution [PDF]

, 2004

openalex   +1 more source

O‐GlcNAc Transferase Promotes Metabolic Dysfunction‐Associated Steatotic Liver Disease‐Related Hepatocellular Carcinoma by Facilitating the Degradation of PTEN

MedComm – Oncology, Volume 4, Issue 4, December 2025.
Lipid‐rich and hypoxia tumor microenvironment elevates O‐GlcNAc transferase (OGT) expression, catalyzing O‐GlcNAcylation of phosphatase and tensin homolog deleted on chromosome ten (PTEN) which in turn negatively regulates PTEN to promotes the growth of hepatocellular carcinoma (HCC).
Haoran Liu, Suming Pu, Wenxin Zhu, Jing Huang, Jianming Li   +4 more
wiley   +1 more source

Rice black-streaked dwarf virus-encoded P6 protein impairs OsPelota-mediated antiviral RNA decay defense via promoting OsSCE1b ubiquitination and degradation in rice. [PDF]

J Integr Plant Biol
The P6 protein encoded by rice black‐streaked dwarf virus enhances degradation of the rice SUMO E2 conjugating enzyme OsSCE1b through the ubiquitin/26S proteasome pathway; OsSCE1b degradation results in decreased SUMOylation of OsPelota, thereby suppressing RNA decay‐dependent antiviral defenses in rice. ABSTRACT Rice black‐streaked dwarf virus (RBSDV)
Xie Y, Zeng M, Wang D, Gao SB, Li L, Zheng L, Zhang Y, Fei S, Zhang C, Wang Y, Zhou X, Wu J.   +11 more
europepmc   +2 more sources