Results 121 to 130 of about 35,698 (247)

Multifaceted roles of SUMO in DNA metabolism

Nucleus
Sumoylation, a process in which SUMO (small ubiquitin like modifier) is conjugated to target proteins, emerges as a post-translational modification that mediates protein−protein interactions, protein complex assembly, and localization of target proteins.
Yee Mon Thu
doaj   +1 more source

Natural variation in OsMYB305 downregulating cytokinin‐mediated inhibition of leaf senescence contributes to regional adaptation in rice

New Phytologist, EarlyView.
Proposed regulatory model of OsMYB305 in leaf senescence. Summary Accumulating evidence has identified transcription factors (TFs) as key regulators of the onset and progression of leaf senescence. However, the regulatory role of the rice myeloblastosis (MYB) TF OsMYB305 in this process remains largely unknown.
Boyeong Kim, Jinah Kim, Yejin Shim, Jinku Kang, Hyeryung Yoon, Sung‐Hwan Cho, Nam‐Chon Paek, Kiyoon Kang   +7 more
wiley   +1 more source

SUMOylation atypique du récepteur nucléaire Nor-1

, 2015
Les récepteurs nucléaires sont des facteurs de transcription régulant l’expression de gènes impliqués dans plusieurs processus physiologiques. En général, ces récepteurs sont activés par une interaction avec un ligand spécifique, mais leur activité peut ...
Gagnon, Jonathan
core  

Identification of Substrates of Protein-Group SUMOylation

, 2016
Protein modification by conjugation to the ubiquitin-related protein SUMO (SUMOylation) regulates numerous cellular functions and is reversible. However, unlike typical posttranslational modifications, SUMOylation often targets and regulates proteins of ...
Psakhye, I., Jentsch, S., Ivan Psakhye, Stefan Jentsch   +3 more
core   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

MYB Factors: Hubs of Plant Stress and Hormone Crosstalk

Plant Biotechnology Journal, EarlyView.
ABSTRACT MYB transcription factors function as main regulatory hubs that integrate environmental signals with multi‐hormonal pathways to synchronize plant growth, metabolism and stress responses. This review delineates the regulatory roles of MYB in the signalling pathway of salicylic acid, jasmonic acid, ethylene and abscisic acid signalling.
Aye Aye Htun, Ya Wang, Jiahao Liu, Zhiqiang Guo, Yi Zheng, Wenjie Wang, Shuting Ma, Aolin Jia, Yan Ren, Feng Chen   +9 more
wiley   +1 more source

Sumoylation inhibits CBS activity.

, 2013
aIn vitro sumoylation of CBS was performed as described under Methods.bThe activity remaining after 6 h of incubation needed for the sumoylation reaction is reported relative to the average of the CBS and CBS+hPc2 assay mixtures (169 µmol h−1 mg−1).
Nitish Agrawal (105325), Ruma Banerjee (45954)   +1 more
core   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

SUMOylation in Trypanosoma brucei

, 2013
Small ubiquitin like modifier (SUMO) proteins are involved in many processes in eukaryotes. We here show that Trypanosoma brucei SUMO (Tb927.5.3210) modifies many proteins.
Christine Clayton, Cornelia Andrea Klein, Dorothea Droll   +2 more
core   +1 more source

SUMOylation-Mediated Response to Mitochondrial Stress

, 2020
Mitochondrial stress is considered as a factor that reprograms the mitochondrial biogenesis and metabolism. As known, SUMOylation occurs through a series of stress-induced biochemical reactions. During the process of SUMOylation, the small ubiquitin-like
Jianli He, Jinke Cheng, Tianshi Wang
core   +1 more source