Results 131 to 140 of about 31,613 (261)
Positive and negative regulation of APP amyloidogenesis by sumoylation
Yonghong Li +5 more
openalex +1 more source
Sumoylation modulates transcriptional activity of MITF in a promoter‐specific manner [PDF]
Hideki Murakami, Heinz Arnheiter
openalex +1 more source
Conformational Rearrangement of Fission DSPs
Assembly properties of fission DSPs. Fission DSPs exist in a dynamic equilibrium of oligomer states in the cytosol, where they must be activated by partner proteins or lipid to induce assembly, and upon GTP hydrolysis, constriction. ABSTRACT Dynamin superfamily proteins (DSPs) are large GTPases that play crucial roles in membrane remodeling processes ...
Anelise N. Hutson +2 more
wiley +1 more source
p14ARF Interacts with the SUMO-Conjugating Enzyme Ubc9 and Promotes the Sumoylation of Its Binding Partners [PDF]
Nadia Barboule +2 more
openalex +1 more source
ASD, a natural plant product screened from small molecule compound library, is an antiobesity agent in mice. ASD promotes BAT thermogenesis to inhibit body weight gain. USP4 was identified and validated as a direct molecular target of ASD. ASD‐induced thermogenesis is modulated by a USP4–PPARγ–UCP1 axis.
Lang Chen +13 more
wiley +1 more source
Collaboration between two conserved sequence motifs drives ATPase stimulation of Hsp90 by Aha1
Abstract Hsp90 is a dimeric molecular chaperone essential for the folding, stabilization, activation, and maturation of hundreds of client proteins, which are critical for cellular function. Co‐chaperones, such as Aha1, play a key role in regulating the ATP‐dependent Hsp90 client activation cycle by modulating Hsp90's ATPase activity and controlling ...
Desmond Prah Amoah +4 more
wiley +1 more source
Histone sumoylation is associated with transcriptional repression
Yuzuru Shiio, Robert N. Eisenman
openalex +1 more source
Pias1 Interaction and Sumoylation of Metabotropic Glutamate Receptor 8 [PDF]
Zhongshu Tang +3 more
openalex +1 more source
Summary Cytoplasmic biomolecular condensates are membrane‐less structures important for cell homeostasis, especially during stress conditions. These aggregates concentrate RNA, protein, and metabolites during a wide variety of stresses. The formation of cytoplasmic biomolecular condensates was studied extensively in plants, revealing many key actors ...
Margaux Legoux +2 more
wiley +1 more source

