Results 141 to 150 of about 31,613 (261)

Research Progress of RAD51AP1 in Malignant Tumors of the Female Reproductive System

open access: yesThe FASEB Journal, Volume 39, Issue 20, 31 October 2025.
RAD51AP1 is highly expressed in malignant tumors of the female reproductive system, exerting a pro‐carcinogenic effect and showing a close association with poor prognosis. High expression of RAD51AP1 can promote tumor cell proliferation, invasion, migration, and stemness maintenance, inhibit apoptosis, and mediate chemoresistance as well as ...
Chengguo Zhang   +5 more
wiley   +1 more source

Decoding Glycosylation in Neurodegenerative Diseases: Mechanistic Insights and Therapeutic Opportunities

open access: yesThe FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Graphical summary of glycosylation impairments in various neurodegenerative disorders. Among the diverse forms of glycosylation, the most extensively studied include N‐glycosylation, O‐glycosylation, and O‐GlcNAcylation. Aberrant glycosylation has been implicated in multiple neurodegenerative conditions.
Haihan Yu   +5 more
wiley   +1 more source

Ubc9- and Mms21-Mediated Sumoylation Counteracts Recombinogenic Events at Damaged Replication Forks [PDF]

open access: bronze, 2006
Dana Branzei   +8 more
openalex   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

open access: yesFEBS Open Bio, Volume 15, Issue 10, Page 1552-1569, October 2025.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis   +3 more
wiley   +1 more source

Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility

open access: yesAdvanced Therapeutics, Volume 8, Issue 10, October 2025.
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam   +5 more
wiley   +1 more source

Coordinated Regulation of AIB1 Transcriptional Activity by Sumoylation and Phosphorylation [PDF]

open access: hybrid, 2006
Huijian Wu   +12 more
openalex   +1 more source

Asprosin Aggravates Tubular Epithelial Cell Injury and Phenotypic Transformation via Mitochondrial Dynamics Disorder Mediated by Excessive Drp1 SUMOylation in Diabetic Nephropathy Mice

open access: yesAdvanced Science, Volume 12, Issue 39, October 20, 2025.
ASP aggravates TEC injury and phenotypic transformation via mitochondrial dynamics disorder mediated by excessive Drp1 SUMOylation in DKD mice. However, either ASP deficiency or AASP effectively alleviates the kidney injury and mitochondrial dynamics disorder induced by STZ/HFD, highlighting that ASP could be an early diagnostic marker and potential ...
Qianqian Huang   +8 more
wiley   +1 more source

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