Results 141 to 150 of about 31,613 (261)
Evolution of a signalling system that incorporates both redundancy and diversity:ArabidopsisSUMOylation [PDF]
Renée J. Chosed +3 more
openalex +1 more source
Research Progress of RAD51AP1 in Malignant Tumors of the Female Reproductive System
RAD51AP1 is highly expressed in malignant tumors of the female reproductive system, exerting a pro‐carcinogenic effect and showing a close association with poor prognosis. High expression of RAD51AP1 can promote tumor cell proliferation, invasion, migration, and stemness maintenance, inhibit apoptosis, and mediate chemoresistance as well as ...
Chengguo Zhang +5 more
wiley +1 more source
Phosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activity [PDF]
Jungseog Kang +2 more
openalex +1 more source
Graphical summary of glycosylation impairments in various neurodegenerative disorders. Among the diverse forms of glycosylation, the most extensively studied include N‐glycosylation, O‐glycosylation, and O‐GlcNAcylation. Aberrant glycosylation has been implicated in multiple neurodegenerative conditions.
Haihan Yu +5 more
wiley +1 more source
Ubc9- and Mms21-Mediated Sumoylation Counteracts Recombinogenic Events at Damaged Replication Forks [PDF]
Dana Branzei +8 more
openalex +1 more source
Matrix: a complex amalgam of structures and functions in tumor microenvironment
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis +3 more
wiley +1 more source
Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility
This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam +5 more
wiley +1 more source
Coordinated Regulation of AIB1 Transcriptional Activity by Sumoylation and Phosphorylation [PDF]
Huijian Wu +12 more
openalex +1 more source
ASP aggravates TEC injury and phenotypic transformation via mitochondrial dynamics disorder mediated by excessive Drp1 SUMOylation in DKD mice. However, either ASP deficiency or AASP effectively alleviates the kidney injury and mitochondrial dynamics disorder induced by STZ/HFD, highlighting that ASP could be an early diagnostic marker and potential ...
Qianqian Huang +8 more
wiley +1 more source

