Results 91 to 100 of about 21,065 (189)

Model for the Interaction of T-cell Receptors with Peptide/MHC Complexes [PDF]

open access: yes, 1989
The immune response against a viral infection is mediated by two different types of cells known as B and T lymphocytes. The receptor on the B cell is the well-characterized antibody molecule, which exists in a membrane-bound form and in a secreted form ...
Bjorkman, P. J., Davis, M. M.
core   +1 more source

Human scFvs That Counteract Bioactivities of Staphylococcus aureus TSST-1

open access: yesToxins, 2017
Some Staphylococcus aureus isolates produced toxic shock syndrome toxin-1 (TSST-1) which is a pyrogenic toxin superantigen (PTSAg). The toxin activates a large fraction of peripheral blood T lymphocytes causing the cells to proliferate and release ...
Thunchanok Rukkawattanakul   +6 more
doaj   +1 more source

Staphylococcal Enterotoxin C Is an Important Virulence Factor for Mastitis

open access: yesToxins, 2019
Staphylococcus aureus is an important bacterial pathogen causing bovine mastitis, but little is known about the virulence factor and the inflammatory responses in the mammary infection.
Rendong Fang   +8 more
doaj   +1 more source

Characteristics of Staphylococcus aureus infections to consider in designing an effective vaccine. [PDF]

open access: yes, 2010
_Staphylococcus aureus_ is a very versatile and adaptable microorganism. It can potentially infect virtually any host tissue. Given the appropriate conditions it can become a life-threatening pathogen, or a commensal colonizer of the nose.
Beatriz E. Baca   +2 more
core   +1 more source

Pathogenesis of polymyalgia rheumatica [PDF]

open access: yes, 2018
Polymyalgia rheumatica (PMR) is a chronic, inflammatory disorder of unknown cause, almost exclusively occurring in people aged over 50 and often associated with giant cell arteritis.
Ciccia F.   +4 more
core   +1 more source

Transcytosis, Antitumor Activity and Toxicity of Staphylococcal Enterotoxin C2 as an Oral Administration Protein Drug

open access: yesToxins, 2016
Staphylococcal enterotoxin C2 (SEC2) is a classical superantigen (SAg), which can tremendously activate T lymphocytes at very low dosage, thus exerting its powerful antitumor activity.
Wenbin Zhao   +6 more
doaj   +1 more source

FDA-approved immunosuppressants targeting staphylococcal superantigens: mechanisms and insights

open access: yesImmunoTargets and Therapy, 2017
Teresa Krakauer Department of Immunology, Molecular Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD, USA Abstract: Immunostimulating staphylococcal enterotoxin B (SEB)
Krakauer T
doaj  

Staphylococcal enterotoxins in the Etiopathogenesis of Mucosal Autoimmunity within the Gastrointestinal Tract

open access: yesToxins, 2014
The staphylococcal enterotoxins (SEs) are the products of Staphylococcus aureus and are recognized as the causative agents of classical food poisoning in humans following the consumption of contaminated food.
MaryAnn Principato, Bi-Feng Qian
doaj   +1 more source

Clinical Snapshot of Group A Streptococcal Isolates from an Australian Tertiary Hospital

open access: yesPathogens
Streptococcus pyogenes (Group A Streptococcus, GAS) is a human-restricted pathogen that causes a wide range of diseases from pharyngitis and scarlet fever to more severe, invasive infections such as necrotising fasciitis and streptococcal toxic shock ...
Phoebe K. Shaw   +7 more
doaj   +1 more source

Narcolepsy: autoimmunity, effector T cell activation due to infection, or T cell independent, major histocompatibility complex class II induced neuronal loss? [PDF]

open access: yes, 2017
Human narcolepsy with cataplexy is a neurological disorder, which develops due to a deficiency in hypocretin producing neurons in the hypothalamus. There is a strong association with human leucocyte antigens HLA-DR2 and HLA-DQB1*0602.
Bassetti, Claudio L.   +5 more
core  

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