Results 101 to 110 of about 12,609 (207)

Bacterial superantigens [PDF]

Clinical and Experimental Immunology, 2003
T, Proft, J D, Fraser
openaire   +2 more sources

Molecular characterization of bovine CD26 upregulated by a staphylococcal superantigen

, 2013
In this report, we describe the cloning, sequencing, and expression of the bovine orthologue of CD26 (BoCD26). Several monoclonal antibodies specific for a molecule, activation molecule 3 (ACT3), aberrantly expressed on superantigen-stimulated bovine CD8+
Hamilton, M. Jo, Naessens, Jan, Sang-Un Lee, Young-Ho Park, Bohach, G.A., Davis, W.C.   +5 more
core  

Table_1_Essential Domain-Dependent Roles Within Soluble IgG for in vivo Superantigen Properties of Staphylococcal Protein A: Resolving the B-Cell Superantigen Paradox.PDF

, 2018
Staphylococcus aureus is a common commensal and frequent opportunistic pathogen that causes invasive infections that often recur. Co-evolution with the host has led to the development of toxins that affect diverse immune cell types.
Carl S. Goodyear (176375), Alejandro J. Ulloa-Morales (5767523), Gregg J. Silverman (554812)   +2 more
core   +1 more source

Skin colonization by superantigen-producing Staphylococcus aureus in Egyptian patients with atopic dermatitis and its relation to disease severity and serum interleukin-4 level

, 2012
SummaryObjectiveThe objective of the current study was to detect Staphylococcus aureus colonization and the presence of superantigen in atopic dermatitis (AD) in Egyptian patients, and to determine its effect on disease severity and serum interleukin (IL)
Rabee Abu Baker, Hesham A. Nada, Atef Elakhras, Gomaa, Nahed I.M., Roshdy Wasfy, Nada, Hesham A., Elakhras, Atef, Wasfy, Roshdy, Baker, Rabee Abu, Nahed I.M. Gomaa   +9 more
core   +1 more source

Mouse mammary tumor viruses with functional superantigen genes are selected during in vivo infection.

, 1995
Mouse mammary tumor virus (MMTV) encodes a superantigen that is important for viral infectivity in vivo. To determine whether superantigen function was required for infection by milk-borne MMTV, we created HYB PRO/Cla transgenic mice.
Jaffe, A B, Golovkina, T V, Ross, S R, Dudley, J P   +3 more
core  

Negative Selection by IgM Superantigen Defines a B Cell Central Tolerance Compartment and Reveals Mutations Allowing Escape

, 2011
To analyze B lymphocyte central tolerance in a polyclonal immune system, mice were engineered to express a superantigen reactive to IgM of allotype b (IgMb). IgMb/b mice carrying superantigen were severely B cell lymphopenic, but small numbers of B cells
Miyo Aoki-Ota, José Luis Vela, Djemel Ait-Azzouzene, David Nemazee, Amanda Lee Gavin, Bao Hoa Duong, Takayuki Ota, Anthony Byron Cooper   +7 more
core   +1 more source

Continuous Oral Administration of the Superantigen Staphylococcal Enterotoxin C2 Activates Intestinal Immunity and Modulates the Gut Microbiota in Mice

Advanced Science
Staphylococcal Enterotoxin C2 (SEC2), a classical superantigen, is an antitumor immunotherapy agent. However, the injectable formulation of SEC2 limits its clinical application.
Wu Gu, Huiwen Zhang, Zhichun Zhang, Mingkai Xu, Xiang Li, Zhiyang Han, Xuanhe Fu, Xu Li, Xiujuan Wang, Chenggang Zhang   +9 more
doaj   +1 more source

Viral Superantigen Drives Extrafollicular and Follicular B Cell Differentiation Leading to Virus-specific Antibody Production

, 1997
Mouse mammary tumor virus (MMTV[SW]) encodes a superantigen expressed by infected B cells. It evokes an antibody response specific for viral envelope protein, indicating selective activation of antigen-specific B cells.
Hans Acha-Orbea, Acha-Orbea, H., Sanjiv A. Luther, Gulbranson-Judge, A., MacLennan, I.C., Luther, S.A., Ian C.M. MacLennan, Adam Gulbranson-Judge   +7 more
core   +1 more source

Early neutralizing antibody response against mouse mammary tumor virus: critical role of viral infection and superantigen-reactive T cells.

, 1997
Infectious mouse mammary tumor virus (MMTV) is a retrovirus that expresses a superantigen shortly after infection of B cells. The superantigen first drives the polyclonal activation and proliferation of superantigen-reactive CD4+ T cells, which then ...
Acha-Orbea, H., Luther, S.A., Maillard, I., Luthi, F., Scarpellino, L., Diggelmann, H.   +5 more
core  

High‐Affinity Superantigen‐Based Trifunctional Immune Cell Engager Synergizes NK and T Cell Activation for Tumor Suppression

Advanced Science
The development of immune cell engagers (ICEs) can be limited by logistical and functional restrictions associated with fusion protein designs, thus limiting immune cell recruitment to solid tumors.
Yao‐An Yu, Wan‐Ju Lien, Wen‐Ching Lin, Yi‐Chung Pan, Sin‐Wei Huang, Chung‐Yuan Mou, Che‐Ming Jack Hu, Kurt Yun Mou   +7 more
doaj   +1 more source