Results 91 to 100 of about 12,609 (207)

Contrasting patterns of streptococcal superantigen-induced T-cell proliferation in guttate vs. chronic plaque psoriasis

, 2001
Background Streptococcal infection is strongly associated with guttate psoriasis (GP) and may also exacerbate chronic plaque psoriasis (CPP), possibly through the release of superantigenic toxins. Objectives To investigate superantigen-induced generation
Barker, J N W N, Mallon, E, Allen, M H, Davison, S C   +3 more
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Staphylococcal Enterotoxin A Detection from Rheumatoid Arthritis Patients’ Blood and Synovial Fluid

Electronic Physician, 2016
Introduction: Direct detection of microbial super antigens in synovial fluid of patients with rheumatoid arthritis may be able to guide to the design of cost-effective therapies.
Ramezan Ali Ataee, Mahboobeh Sadat Kahani, Gholam Hossein Alishiri, Zyenab Ahamadi   +3 more
doaj   +1 more source

Nasopharyngeal infection by Streptococcus pyogenes requires superantigen-responsive Vβ-specific T cells

, 2017
Significance Superantigen toxins were defined over 25 years ago for their ability to activate T cells in a T-cell receptor β-chain variable domain-dependent manner.
Joseph J. Zeppa, John K. McCormick, Delfina M. Mazzuca, S. M. Mansour Haeryfar, Ivor Mohorovic, Katherine J. Kasper   +5 more
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Protein Fv: an endogenous immunoglobulin superantigen and superallergen.

, 2007
Protein Fv was isolated and purified by Jean Pierre Bouvet and collaborators in 1990 from stool extracts of patients affected by viral hepatitis B or C.
MARONE, GIANNI, BOUVET J. P
core   +1 more source

Overview of Bacterial Protein Toxins from Pathogenic Bacteria: Mode of Action and Insights into Evolution

Toxins
Bacterial protein toxins are secreted by certain bacteria and are responsible for mild to severe diseases in humans and animals. They are among the most potent molecules known, which are active at very low concentrations. Bacterial protein toxins exhibit
Michel R. Popoff
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Superantigen and HLA-DR ligation induce phospholipase-C gamma 1 activation in class II+ T cells

, 1992
Udgivelsesdato: 1992-Dec-1Bacterial enterotoxin superantigens bind directly to HLA class II molecules (HLA-DR) expressed on both APC and activated human T cells, and simultaneously bind to certain V beta chains of the TCR.
Odum, Niels, Ledbetter, J A, Kanner, S B, Svejgaard, A, Grosmaire, L, Masewicz, S   +5 more
core  

Encoding a superantigen by Staphylococcus aureus does not affect clinical characteristics of infected atopic dermatitis lesions

, 2010
Background: Bacterial infection with Staphylococcus aureus is a known trigger for the worsening of atopic dermatitis (AD). Staphylococcal superantigens have been theorized to make a potential contribution to this worsening of AD seen with infection ...
M.H. Kaplan, Saha, C., Travers, J. B., Kozman, A., Y. Yao, P. Bina, Bina, P., Yao, Y., W. Yao, Yao, W., C. Saha, J.B. Travers, A. Kozman, Kaplan, M. H.   +13 more
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Identification of Three Novel Superantigen-Encoding Genes in Streptococcus equi subsp. zooepidemicus, szeF, szeN, and szeP

, 2010
The acquisition of superantigen-encoding genes by Streptococcus pyogenes has been associated with increased morbidity and mortality in humans, and the gain of four superantigens by Streptococcus equi is ...
Erles, Kerstin, Andrew S. Waller, Karen F. Steward, Robinson, Carl, Anderson, Emma, Waller, Andrew S., Emma Anderson, Wright, N L, AHT, Carl Robinson, Romain Paillot, Efstratiou, A, Paillot, R, Holden, Matthew T. G., Androulla Efstratiou, Liverpool, Jolley, K A, Wellcome Trust Sanger Institute, Katy Webb, Alan Radford, Robinson, C, Holden, M T G, Steward, Karen F., Campi, M C M, Paillot, Romain, Alistair C. Darby, Karen Broughton, Priestnall, S L, HPA, Darby, Alistair C., Jolley, Keith A., Kerstin Erles, Broughton, K, Webb, K, Keith A. Jolley, Maria C. Marotti Campi, Steward, K F, Simon L. Priestnall, Margaret A. Hughes, Hughes, M A, Waller, A S, Hughes, Margaret A., Radford, A D, Erles, K, Broughton, Karen, Webb, Katy, Oxford, Matthew T. G. Holden, Radford, Alan, Anderson, E, Darby, A C, Wright, Nicola L., Efstratiou, Androulla, Campi, Maria C. Marotti, Nicola L. Wright, Priestnall, Simon L., Al Khaledia Equine Hospital   +56 more
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Image_2_Essential Domain-Dependent Roles Within Soluble IgG for in vivo Superantigen Properties of Staphylococcal Protein A: Resolving the B-Cell Superantigen Paradox.TIFF

, 2018
Staphylococcus aureus is a common commensal and frequent opportunistic pathogen that causes invasive infections that often recur. Co-evolution with the host has led to the development of toxins that affect diverse immune cell types.
Carl S. Goodyear (176375), Alejandro J. Ulloa-Morales (5767523), Gregg J. Silverman (554812)   +2 more
core   +1 more source

FDA-approved immunosuppressants targeting staphylococcal superantigens: mechanisms and insights

ImmunoTargets and Therapy, 2017
Teresa Krakauer Department of Immunology, Molecular Translational Sciences Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD, USA Abstract: Immunostimulating staphylococcal enterotoxin B (SEB)
Krakauer T
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