Results 111 to 120 of about 318,307 (167)
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The Reaction of no With Superoxide

Free Radical Research Communications, 1993
The rate constant for the reaction of NO with .O2- was determined to be (6.7 +/- 0.9) x 10(9) l mol-1 s-1, considerably higher than previously reported. Rate measurements were made from pH 5.6 to 12.5 both by monitoring the loss of .O2- and the formation of the product -OONO.
S Padmaja, Robert E Huie
exaly   +3 more sources

Superoxide, Superoxide Dismutase and the Respiratory Burst

Veterinary Clinical Pathology, 1983
SummaryPhagocytes undergo a sharp burst of oxygen consumption when engulfing bacteria. This oxygen is enzymatically reduced to toxic metabolites which are essential to the bactericidal action of the cell. Oxygen metabolites formed in this burst as well as other intermediates formed in biological reduction reactions do not selectively reserve their ...
H S, Bender, W R, Chickering
openaire   +2 more sources

Superoxide Dismutase Mimetics

Pulmonary Pharmacology and Therapeutics, 2002
In this review we describe the potential role(s) of superoxide in inflammatory disorders.
Salvatore Cuzzocrea, Carolina Muscoli
exaly   +4 more sources

SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES

Annual Review of Biochemistry, 1972
O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH.. SODs inhibit such HO. production by scavengingO2-, but Cu, ZnSODs, by virtue of a nonspecific peroxidase activity, may peroxidize spin trapping agents and thus give the appearance of catalyzing OH ...
openaire   +2 more sources

Theoretical Studies of Manganese and Iron Superoxide Dismutases:  Superoxide Binding and Superoxide Oxidation

The Journal of Physical Chemistry B, 2005
Density-functional calculations indicate that the second sphere of coordination around the metal centers of manganese and iron superoxide dismutases (MnSODs and FeSODs) plays an important role in the binding of O2(-). In these systems, O2(-) prefers to bind to Mn or Fe in end-on configurations. For human and E.
Isabel A, Abreu   +2 more
openaire   +2 more sources

Superoxidation of Retinoic Acid

Photochemistry and Photobiology, 2006
Atmospheric pressure chemical ionization mass spectroscopy (APCI-MS) was used to examine the light-induced oxidation products of retinoic acid under conditions that favor and preclude its aggregation. We observed that in conditions that favor aggregation, i.e. in aqueous solutions, retinoic acid undergoes superoxidation to yield highly oxidized species.
Ilyas, Washington   +2 more
openaire   +2 more sources

Engineered Superoxide Dismutase Monomers for Superoxide Biosensor Applications

Analytical Chemistry, 2005
Because of its high reaction rate and specificity, the enzyme superoxide dismutase (SOD) offers great potential for the sensitive quantification of superoxide radicals in electrochemical biosensors. In this work, monomeric mutants of human Cu,Zn-SOD were engineered to contain one or two additional cysteine residues, which could be used to bind the ...
Beissenhirtz, Moritz Karl   +3 more
openaire   +2 more sources

Superoxide dismutase

Parasitology Today, 1994
Eric James here discusses the molecular forms of superoxide dismutase and looks at its potential role in the pathogenesis of parasitic infections.
openaire   +2 more sources

Superoxide Radical and Superoxide Dismutases: Threat and Defense

1980
An enzymic flux of O2- and H2O2 caused strand breaks in the supercoiled covalently closed circular Col El plasmid. Subnanomolar levels of superoxide levels of superoxide dismutase or of catalase prevented this attack on DNA, signifying that both O2- and H2O2 were required.
K, Brawn, I, Fridovich
openaire   +2 more sources

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