Results 121 to 130 of about 442,139 (308)

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Superoxide Anions Inhibit Intracellular Calcium Response in Porcine Airway Smooth Muscle Cells

American Journal of Perinatology Reports
Background Superoxide anions (O2 −) have multiple effects on pulmonary parenchyma altering cell proliferation, cellular metabolism, and airway smooth muscle (ASM) contraction.
Ramesh Krishnan, Mathur S. Kannan, Deepak A. Deshpande   +2 more
doaj   +1 more source

Synergy of Pd Clusters and TiO2 {101} for Photocatalytic Nonoxidative Coupling of Methane

Advanced Science, EarlyView.
This study presents photocatalytic nonoxidative coupling of methane over cal‐Pd0.05/TiO2{101}, achieving near 100% selectivity and long‐term stability under mild flow conditions through synergistic single atoms and clusters catalysis. ABSTRACT Photocatalytic nonoxidative coupling of methane (NOCM) offers a sustainable route to valorize CH4 into C2 ...
Jianlong Yang, Annika S. Tang, Junwang Tang   +2 more
wiley   +1 more source

Regulation of the microglial NADPH oxidase by neurotransmitters: implications for microglial – neuronal interactions [PDF]

, 2012
Neurotransmitter dysregulation and reactive oxygen species (ROS) are a hallmark of neurodegenerative disease. Microglia, the immune cells of the CNS, express three NADPH oxidase isoforms (Nox1, Nox2 and Nox4), which produce superoxide that is used as an ...
Mead, E.L.
core  

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

RvD2 mitigates TNFɑ-Induced mitochondrial reactive oxygen species through NRF2 signaling in placental trophoblasts

Frontiers in Physiology
IntroductionHypertensive disorders of pregnancy (HDP) are marked by elevated levels of TNFα, which increases reactive oxygen species (ROS) and disrupts metabolism of trophoblasts. Resolvin D2 (RvD2), an omega‐3 fatty acid-derived lipid mediator, is known
Taija Hahka, Taija Hahka, Taija Hahka, Deekshika Sekar, Prakash Kumar Sahoo, Aiswariya Ravi, Colman Freel, Colman Freel, Chandan Krishnamoorthy, Sankar Ramamurthy, Rebekah Rapoza, Rebecca Drakowski, Anum Akbar, Matt VanOrmer, Melissa Thoene, Corrine K. Hanson, Tara Nordgren, Sathish Kumar Natarajan, Sathish Kumar Natarajan, Ann Anderson Berry, Ann Anderson Berry   +20 more
doaj   +1 more source

Superoxide dismutase inhibitor screening and characterization using ¹?F NMR [PDF]

, 2010
Superoxide dismutase enzymes (SOD) catalyze the disproportionation of superoxide to form molecular oxygen and hydrogen peroxide in a cyclic mechanism. SODs prevent the formation of hydroxyl radicals, preventing apoptosis.
NC DOCKS at Western Carolina University, Arrington, Megan Elizabeth   +1 more
core  

Stage‐Adaptive Janus Microneedle System for Redox‐Immune Regulation and Mitochondrial Protection in Infected Diabetic Wound Healing

Advanced Science, EarlyView.
ABSTRACT Infected diabetic wounds are sustained by a vicious cycle of hyperglycemia‐driven bacterial infection, persistent oxidative stress, and excessive inflammation, which collectively disrupt the ordered progression of tissue repair. Here, we engineered a stage‐adaptive Janus microneedle patch (MN‐FeSAC‐PPE) to enable a staged therapeutic process ...
Mengting Yin, Yu Zhang, Xinyu Qu, Jiayi Liu, Zhongyi Sun, Haibo Liu, Ziyan Chen, Jing Ru, Jingwen Han, Bingqiang Lu, Yan Lu, Yan Wang, Xinyu Zhao, Feng Chen   +13 more
wiley   +1 more source

Simultaneous Wastewater‐to‐Hydrogen Upgrading via Mechanically Driven Piezocatalysis Over Ag‐ZnO Nanorods

Advanced Science, EarlyView.
A piezocatalytic strategy enables simultaneous wastewater purification and hydrogen generation by harnessing mechanical energy. Complementary piezo‐induced charges are selectively directed toward oxidation and reduction pathways, achieving efficient pollutant degradation and continuous H2 evolution.
Yiqing Wei, Jianghai Huang, Yejunchi Zhang, Yang Wang, Dongmei Li, Chaogang Ban, Peng Yu, Jiangping Ma, Zhenxiang Cheng   +8 more
wiley   +1 more source

Superoxide and superoxide dismutase in pulmonary hypoxic vasoconstriction [PDF]

, 2002
Superoxide is known to cause vascular damage and can consume protective NO that maintains a low pulmonary pressure. There is evidence suggesting that hypoxia upregulates NADH/NADPH oxidase and xanthine oxidase in the smooth muscle and endothelial cells ...
Wadsworth, R.M., Milliken, P.H.
core   +2 more sources