Results 11 to 20 of about 360,631 (277)
Mitochondrial Superoxide Dismutase in Cisplatin-Induced Kidney Injury
Cisplatin is a chemotherapy agent commonly used to treat a wide variety of cancers. Despite the potential for both severe acute and chronic side effects, it remains a preferred therapeutic option for many malignancies due to its potent anti-tumor ...
Kranti A. Mapuskar+11 more
doaj +1 more source
The landscape of cognitive impairment in superoxide dismutase 1-amyotrophic lateral sclerosis
Although mutations in the superoxide dismutase 1 gene account for only a minority of total amyotrophic lateral sclerosis cases, the discovery of this gene has been crucial for amyotrophic lateral sclerosis research. Since the identification of superoxide
Ilaria Martinelli+6 more
doaj +1 more source
The crystal structure of superoxide dismutase from Plasmodium falciparum [PDF]
Background: Superoxide dismutases (SODs) are important enzymes in defence against oxidative stress. In Plasmodium falciparum, they may be expected to have special significance since part of the parasite life cycle is spent in red blood cells where the ...
Boucher, Ian W.+6 more
core +3 more sources
Abstract Fresh chicken liver contains two types of superoxide dismutase, one of which is localized in the mitochondria while the other is found in the cytosol. The mitochondrial superoxide dismutase was inactivated by treatment with mixtures of chloroform and ethanol whereas the cytosol superoxide dismutase was not. The cytosol superoxide dismutase was
Richard A. Weisiger, Irwin Fridovich
openaire +2 more sources
The Cu,Zn Superoxide Dismutase: not only a dismutase enzyme
The Cu,Zn superoxide dismutase (SOD1) is an ubiquitary cytosolic dimeric carbohydrate free molecule, belonging to a family of isoenzymes involved in the scavenger of superoxide anions.
Paolo Mondola+3 more
doaj +1 more source
Polymer coated cerium oxide nanoparticles as oxidoreductase-like catalysts [PDF]
Cerium oxide nanoparticles have been shown to mimic oxidoreductase enzymes by catalyzing the decomposition of organic substrates and reactive oxygen species. This mimicry can be found in superoxide radicals and hydrogen peroxides, harmful molecules produced in oxidative stress asso-ciated diseases.
arxiv +1 more source
The protective effect of M40401, a superoxide dismutase mimetic, on post-ischemic brain damage in Mongolian gerbils [PDF]
BACKGROUND: Overproduction of free radical species has been shown to occur in brain tissues after ischemia-reperfusion injury. However, most of free radical scavengers known to antagonize oxidative damage (e.g. superoxide dismutase, catalase), are unable
Granato, Teresa+8 more
core +2 more sources
ASSOCIATION BETWEEN BLOOD DONATION FREQUENCY, ANTIOXIDANT ENZYMES AND LIPID PEROXIDATION [PDF]
"nIron is a pro-oxidant cofactor that may be linked to atherosclerosis progression. Free iron catalyzes the generation of free radicals and free radicals promote the oxidation of lipids.
M Mehrabani+6 more
doaj +2 more sources
Expression of Extracellular Superoxide Dismutase Protein in Diabetes [PDF]
Background Diabetes is characterized by chronic hyperglycemia, which can increase reactive oxygen species (ROS) production by the mitochondrial electron transport chain.
Chul Han Kim
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Superoxide Dismutases and Superoxide Reductases
Superoxide, O2•–, is formed in all living organisms that come in contact with air, and, depending upon its biological context, it may act as a signaling agent, a toxic species, or a harmless intermediate that decomposes spontaneously. Its levels are limited in vivo by two different types of enzymes, superoxide reductase (SOR) and superoxide dismutase ...
Isabel A. Abreu+7 more
openaire +3 more sources